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Asarone injection

Function and Efficacy

1. Pharmacology This product has the effects of relieving asthma, relieving cough, expectorant, sedative, antispasmodic, and anticonvulsant. Relieving asthma: It can counteract histamine and acetylcholine and relieve bronchospasm; relieving cough: It has a strong inhibitory effect on the cough center; expectorant: It causes increased secretion, thins thick sputum, reduces sputum viscosity, and is easy to cough out; sedative: It has a sedative effect close to diazepam, significantly reduces spontaneous activity without inhibitory effect; antispasmodic: It is similar to aminophylline and has the effect of relaxing bronchial smooth muscle. Anticonvulsant: It can increase the electrical stimulation threshold of the cerebral cortex, inhibit the synaptic conduction of electrical stimulation and the spread of epileptic electricity, thereby preventing or alleviating epileptic seizures. 2. Toxicology The LD50 of oral and intraperitoneal injection of α-asarone in mice is (680.5±41.6) mg/kg and (388.7±28.5) mg/kg, respectively. The minimum lethal dose (MLD) of intravenous injection in rabbits is (66.3±10.0) mg/kg.

Ingredients

The main ingredient of this product is α-asarone, and its chemical name is: 2,4,5-trimethoxy-1-propenylbenzene.

Name Description Content CAS NO. Manufacturer
alpha-AsaroneIngredients

It has the effects of relieving asthma, relieving cough, removing phlegm, sedation, antispasmodic, and anticonvulsant. Relieving asthma: It can counteract histamine and acetylcholine and relieve bronchospasm; relieving cough: It has a strong inhibitory effect on the cough center; removing phlegm: It causes increased secretion, thins thick sputum, reduces sputum viscosity, and makes it easier to cough up; sedation: It has a sedative effect close to diazepam, significantly reduces spontaneous activity without an inhibitory effect; antispasmodic: It is similar to aminophylline and has the effect of relaxing bronchial smooth muscles. Anticonvulsant: It can increase the electrical stimulation threshold of the cerebral cortex, inhibit the synaptic conduction of electrical stimulation and the spread of epileptic electricity, thereby preventing or alleviating epileptic seizures.

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Appearance

This product is a colorless to light yellow clear liquid with a slightly milky white fluorescence.

Indication

This product is mainly used for pneumonia, bronchial asthma, chronic obstructive pulmonary disease with acute lung inflammation, etc.

Usage and Dosage

1. Intravenous push: 16-24 mg once, diluted in 40 ml of 20% glucose injection, slowly intravenously pushed, 2-3 times a day. The dosage for children is reduced as appropriate. 2. Intravenous drip: 16-24 mg once for adults, 0.5 mg/kg once for children, diluted with 5% or 10% glucose injection to a 0.01%-0.02% solution, intravenously drip, 2 times a day.

Adverse Reactions

A small number of patients experience palpitations and chest tightness after injection of this drug. The injection speed should be slowed down or the dose should be reduced appropriately; shock is rare.

Precautions

It is contraindicated for those who are allergic to this product. [Use in pregnant and lactating women] It is not clear yet.

Special Population Medication

Precautions for children: This product has not been tested and there is no reliable reference. Precautions for pregnancy and lactation: Use with caution in pregnant and lactating women. Precautions for the elderly: This product has not been tested and there is no reliable reference.

Drug Interactions

1. It has a synergistic effect on the central nervous system when used in combination with reserpine or chlorpromazine. 2. This product can enhance the hypnotic effect of barbiturates.

Storage

Keep away from light and store in airtight container.

Packaging Specification

10ml:24mg

Validity Period

24 months.

Manufacturer

Liaoning Yuhuang Pharmaceutical Co., Ltd.

  • Founded in:

    2005-01-26
  • Address:

    No. 5-5, Jialin Road, Sujiatun District, Shenyang City, Liaoning Province
  • Tax NO.:

    912101117695668202
  • Registered Funds:

    14 million yuan
  • Email:

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