Methylcobalamin capsules
Function and Efficacy
Pharmacological action: This product is an endogenous coenzyme B12 that participates in the one-carbon unit cycle and plays an important role in the transmethylation reaction of methionine synthesis from homocysteine. Animal experiments have found that this product is easier to enter neuronal organelles than cyanocobalamin, participates in the synthesis of thymidine nucleoside in brain cells and spinal cord neurons, promotes the utilization of folic acid and nucleic acid metabolism, and has a stronger effect on promoting nucleic acid and protein synthesis than cyanocobalamin. This product can promote axonal transport function and axonal regeneration, normalize the transport of axonal skeletal proteins in the sciatic nerve of diabetic rats induced by streptozotocin, and has an inhibitory effect on drug-induced neurodegeneration, such as neurodegeneration caused by doxorubicin, acrylamide, and vincristine, and neurological diseases in spontaneously hypertensive rats. In rat tissue culture, it was found that this product can promote lecithin
Ingredients
The main ingredient of this product is methylcobalamin, and its chemical name is: Coα-[α-(5,6-dimethylbenzimidazolyl)]-Coβ-methylcobaltamide.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| MecobalaminIngredients |
This product is an endogenous coenzyme B12, which participates in the one-carbon unit cycle and plays an important role in the transmethylation reaction of synthesizing methionine from homocysteine. Animal experiments have found that this product is easier to enter neuronal organelles than cyanocobalamin, participates in the synthesis of thymidine nucleoside in brain cells and spinal cord neurons, promotes the utilization of folic acid and nucleic acid metabolism, and has a stronger effect on promoting nucleic acid and protein synthesis than cyanocobalamin. This product can promote axonal transport function and axonal regeneration, normalize the transport of axonal skeleton proteins in the sciatic nerve of diabetic rats induced by streptozotocin, and has an inhibitory effect on drug-induced neurodegeneration, such as neurodegeneration caused by doxorubicin, acrylamide, and vincristine, and neurological diseases in spontaneously hypertensive rats. In rat tissue culture, it was found that this product can promote lecithin synthesis. More |
13422-55-4 | 28 |
Appearance
This product is a capsule, and the contents are pink powder.
Indication
Peripheral neuropathy.
Usage and Dosage
Oral administration. Usually 0.5 mg per time, 3 times a day for adults, the dosage can be increased or decreased according to age and symptoms.
Adverse Reactions
1 Allergy: Occasionally, rash may occur (incidence rate: 2 Others: Occasionally (incidence rate: 5% to 0.1%): loss of appetite, nausea, vomiting, diarrhea.
Precautions
It is contraindicated in patients with a history of hypersensitivity to methylcobalamin or any of the excipients in the formulation.
Special Population Medication
Precautions for children: Not clear yet. Precautions for pregnancy and lactation: Although methylcobalamin did not show teratogenic effects in animal experiments, its safety for pregnant women is not clear yet. It is not clear whether methylcobalamin is secreted through women's breast milk, but animal experiments report that methylcobalamin is secreted into breast milk. The safety of this product in lactating women is not clear yet. Precautions for the elderly: Due to the decline in function of the elderly, it is recommended to reduce the dosage as appropriate under the guidance of a doctor.
Drug Interactions
Not yet clear.
Storage
Keep away from light and store in sealed container.
Packaging Specification
0.5mg
Validity Period
24 months
Manufacturer
Nantong Huashan Pharmaceutical Co., Ltd.
-
Founded in:
1993-12-24 -
Address:
No. 78 Tongsheng Avenue, Economic and Technological Development Zone, Nantong City, Jiangsu Province (Production and operation address: No. 78 Tongsheng Avenue, Economic and Technological Development Zone, Nantong City, Jiangsu Province, 5th Floor, Building No. 3, Economic and Technological Development Zone, Nantong City, Jiangsu Province) -
Tax NO.:
913206916083078799 -
Registered Funds:
14.4101 million yuan -
Website:
-
Email: