On ECHEMI
Home > Drugs > Methylcobalamin capsules

Methylcobalamin capsules

Function and Efficacy

Pharmacological action: This product is an endogenous coenzyme B12 that participates in the one-carbon unit cycle and plays an important role in the transmethylation reaction of methionine synthesis from homocysteine. Animal experiments have found that this product is easier to enter neuronal organelles than cyanocobalamin, participates in the synthesis of thymidine nucleoside in brain cells and spinal cord neurons, promotes the utilization of folic acid and nucleic acid metabolism, and has a stronger effect on promoting nucleic acid and protein synthesis than cyanocobalamin. This product can promote axonal transport function and axonal regeneration, normalize the transport of axonal skeletal proteins in the sciatic nerve of diabetic rats induced by streptozotocin, and has an inhibitory effect on drug-induced neurodegeneration, such as neurodegeneration caused by doxorubicin, acrylamide, and vincristine, and neurological diseases in spontaneously hypertensive rats. In rat tissue culture, it was found that this product can promote lecithin

Ingredients

The main ingredient of this product is methylcobalamin, and its chemical name is: Coα-[α-(5,6-dimethylbenzimidazolyl)]-Coβ-methylcobaltamide.

Name Description Content CAS NO. Manufacturer
MecobalaminIngredients

This product is an endogenous coenzyme B12, which participates in the one-carbon unit cycle and plays an important role in the transmethylation reaction of synthesizing methionine from homocysteine. Animal experiments have found that this product is easier to enter neuronal organelles than cyanocobalamin, participates in the synthesis of thymidine nucleoside in brain cells and spinal cord neurons, promotes the utilization of folic acid and nucleic acid metabolism, and has a stronger effect on promoting nucleic acid and protein synthesis than cyanocobalamin. This product can promote axonal transport function and axonal regeneration, normalize the transport of axonal skeleton proteins in the sciatic nerve of diabetic rats induced by streptozotocin, and has an inhibitory effect on drug-induced neurodegeneration, such as neurodegeneration caused by doxorubicin, acrylamide, and vincristine, and neurological diseases in spontaneously hypertensive rats. In rat tissue culture, it was found that this product can promote lecithin synthesis.

More
13422-55-4 28

Appearance

This product is a capsule, and the contents are pink powder.

Indication

Peripheral neuropathy.

Usage and Dosage

Oral administration. Usually 0.5 mg per time, 3 times a day for adults, the dosage can be increased or decreased according to age and symptoms.

Adverse Reactions

1 Allergy: Occasionally, rash may occur (incidence rate: 2 Others: Occasionally (incidence rate: 5% to 0.1%): loss of appetite, nausea, vomiting, diarrhea.

Precautions

It is contraindicated in patients with a history of hypersensitivity to methylcobalamin or any of the excipients in the formulation.

Special Population Medication

Precautions for children: Not clear yet. Precautions for pregnancy and lactation: Although methylcobalamin did not show teratogenic effects in animal experiments, its safety for pregnant women is not clear yet. It is not clear whether methylcobalamin is secreted through women's breast milk, but animal experiments report that methylcobalamin is secreted into breast milk. The safety of this product in lactating women is not clear yet. Precautions for the elderly: Due to the decline in function of the elderly, it is recommended to reduce the dosage as appropriate under the guidance of a doctor.

Drug Interactions

Not yet clear.

Storage

Keep away from light and store in sealed container.

Packaging Specification

0.5mg

Validity Period

24 months

Manufacturer

Nantong Huashan Pharmaceutical Co., Ltd.

  • Founded in:

    1993-12-24
  • Address:

    No. 78 Tongsheng Avenue, Economic and Technological Development Zone, Nantong City, Jiangsu Province (Production and operation address: No. 78 Tongsheng Avenue, Economic and Technological Development Zone, Nantong City, Jiangsu Province, 5th Floor, Building No. 3, Economic and Technological Development Zone, Nantong City, Jiangsu Province)
  • Tax NO.:

    913206916083078799
  • Registered Funds:

    14.4101 million yuan
  • Website:

  • Email:

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.