Ampicillin Capsules
Function and Efficacy
This product is a broad-spectrum semi-synthetic penicillin with extremely low toxicity. The antibacterial spectrum is similar to that of penicillin, and it has a strong antibacterial effect on grass-green streptococci, hemolytic streptococci, and enterococci. Diphtheria bacillus, anthrax bacillus, Gram-positive anaerobic cocci and bacilli are sensitive to this product; meningococci, pertussis bacilli, and Brucella are also very sensitive. Escherichia coli, Salmonella, Shigella dysenteriae, Proteus, influenza bacilli, pneumococci, gonococci, etc. have different degrees of drug resistance because some strains produce beta-lactamase. Among them, the resistance rate of Escherichia coli is as high as 50-60%. Enterobacter bacteria, Pseudomonas aeruginosa and anaerobic Gram-negative bacilli are resistant to this product. This product is mainly used to treat infectious diseases caused by sensitive Staphylococcus aureus, hemolytic streptococci, gonococci, meningococci and diphtheria, pertussis, influenza bacilli, Salmonella, Shigella, etc.; such as respiratory tract infections (pneumonia, acute and chronic bronchitis, whooping cough, etc.), gastroenteritis and digestive tract infections (liver and gallbladder infections, acute and chronic gastroenteritis, bacillary dysentery, typhoid and paratyphoid, etc.), urinary tract infections (gonorrhea, urethritis, cystitis, etc.), soft tissue infections and sepsis, meningitis, endocarditis, etc.
Ingredients
Ampicillin
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| AmpicillinIngredients |
This product is a broad-spectrum semi-synthetic penicillin with extremely low toxicity. The antibacterial spectrum is similar to that of penicillin, and it has a strong antibacterial effect on grass-green streptococci, hemolytic streptococci, and enterococci. Diphtheria bacillus, anthrax bacillus, Gram-positive anaerobic cocci and bacilli are sensitive to this product; meningococci, pertussis bacilli, and Brucella are also very sensitive. Escherichia coli, Salmonella, Shigella dysenteriae, Proteus, influenza bacilli, pneumococci, gonococci, etc. have different degrees of drug resistance because some strains produce beta-lactamase. Among them, the resistance rate of Escherichia coli is as high as 50-60%. Enterobacter bacteria, Pseudomonas aeruginosa and anaerobic Gram-negative bacilli are resistant to this product. This product is mainly used to treat infectious diseases caused by sensitive Staphylococcus aureus, hemolytic streptococci, gonococci, meningococci and diphtheria Bordetella, pertussis Bordetella, influenza Bordetella, Salmonella, Shigella, etc.; such as respiratory tract infections (pneumonia, acute and chronic bronchitis, whooping cough, etc.), gastroenteritis and digestive tract infections (liver and gallbladder infections, acute and chronic gastroenteritis, bacillary dysentery, typhoid and paratyphoid, etc.), urinary tract infections (gonorrhea, urethritis, cystitis, etc.), soft tissue infections and sepsis, meningitis, endocarditis, etc. More |
69-53-4 | 26 |
Appearance
After removing the capsule, this product is a white powder, odorless or nearly odorless, with a slightly bitter taste.
Indication
This product is a broad-spectrum semi-synthetic penicillin with extremely low toxicity. The antibacterial spectrum is similar to that of penicillin, and it has a strong antibacterial effect on grass-green streptococci, hemolytic streptococci, and enterococci. Corynebacterium diphtheriae, Bacillus anthracis, Gram-positive anaerobic cocci and bacilli are sensitive to this product; meningococci, Bordetella pertussis, and Brucella are also very sensitive. Escherichia coli, Salmonella, Shigella dysenteriae, Proteus, Bacillus influenzae, Pneumococcus, and Neisseria gonorrhoeae all have varying degrees of drug resistance because some strains produce β-lactamase. Among them, the resistance rate of Escherichia coli is as high as 50-60%. Enterobacter bacteria, Pseudomonas aeruginosa, and anaerobic Gram-negative bacilli are resistant to this product. This product is mainly used to treat sensitive Staphylococcus aureus, hemolytic streptococci, gonococci, meningococci, and Corynebacterium diphtheriae, Bordetella pertussis,
Usage and Dosage
Oral administration on an empty stomach. Common dosage: 2 capsules per time for adults, 1 capsule for children aged 6-12 years. 2/3 capsules for children aged 2-6 years, 3 times a day. Children under 1 year old, 0.05-0.15g per kg of body weight per day, divided into 3-4 times. Or follow the doctor's advice.
Adverse Reactions
Not yet clear
Precautions
1. Patients who are allergic to penicillins or cephalosporins or have a positive penicillin skin test are prohibited from using this product. 2. Patients with uric acid kidney stones, acute gout attacks, and active gastrointestinal ulcers are prohibited from using this product. Children under 32 years old are prohibited from using this product.
Special Population Medication
Precautions for children: It is forbidden to use in children under 3 years old. Precautions for pregnancy and lactation: There are no strict controlled trials for the use of ampicillin in pregnant women, so pregnant women should use this product only when it is necessary. A small amount of ampicillin can be secreted from breast milk, so breastfeeding should be suspended when breastfeeding women take the drug. Precautions for the elderly: Due to the decline of physiological renal function, the dosage should be appropriately reduced.
Drug Interactions
Gentamycin: Penicillin, carbenicillin, ampicillin and other penicillin antibiotics can inactivate gentamicin. Glucose solution (pH 3.2-5.5): Ampicillin is easily inactivated in acidic media, reducing its efficacy. Vitamin C: Can inactivate or reduce the efficacy of ampicillin. Tetracycline: Can reduce the efficacy of penicillin in treating pneumonia, meningitis and scarlet fever. Dietary fiber: Can reduce the absorption of oral ampicillin. Balanced solution: Its lactate root can promote the hydrolysis and efficacy reduction of ampicillin sodium (reduced to 75% in 30 minutes). Indomethacin: Can prolong the half-life of penicillin and increase the blood drug concentration. Aspirin: Can increase the blood concentration of penicillin and prolong the half-life of penicillin from 44.5 minutes to 72.4 minutes (competition for renal tubular secretion). Erythromycin: Can reduce the efficacy of penicillin. For other drug interactions, please consult your doctor or pharmacist.
Storage
Keep sealed.
Packaging Specification
0.25g (calculated as C16H19N3O4S)
Validity Period
3 years
Manufacturer
Sichuan EmeiShan Pharmaceutical Co., Ltd.
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Founded in:
1993-10-19 -
Address:
No. 6 Yingbin Avenue, Leshan High-tech Industrial Development Zone -
Tax NO.:
91511100621103491L -
Registered Funds:
51 million yuan -
Website:
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Email: