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Compound Ketoconazole Ointment

Function and Efficacy

Ketoconazole is an azole antifungal drug. It has antibacterial and bactericidal effects on dermatophytes, yeasts (Candida, Pityrosporum, Torulopsis, Cryptococcus), dimorphic fungi and Fungi; except for Entomophthora, it has weaker effects on Aspergillus, Schenckia, some Phaeochromocytaceae and Mucor. The mechanism of action of ketoconazole is mainly to highly selectively interfere with the activity of fungal cytochrome P-450, thereby inhibiting the biosynthesis of ergosterol on the fungal cell membrane. Clobetasol propionate is a potent topical corticosteroid. It acts quickly and has a strong capillary contraction effect. The anti-inflammatory effect is 112.5 times that of hydrocortisone, 2.3 times that of betamethasone sodium phosphate, and 18.7 times that of fluocinolone. Neomycin sulfate belongs to the aminoglycoside antibiotics and can be used externally to treat local infections.

Ingredients

This product is a compound preparation, containing 10 mg of ketoconazole and 0.5 mg of clobetasol propionate per gram. The excipients are: stearic acid, liquid paraffin, glycerin, cetostearyl alcohol, fenvalerate 0, disodium edetate, 2,6-di-tert-butyl-p-cresol, anhydrous sodium sulfite, vitamin E, laurocapram, Germallplus (preservative), natural moisturizing factor, flavor, ethanol.

Name Description Content CAS NO. Manufacturer
KetoconazoleIngredients

It has antibacterial and bactericidal effects on dermatophytes, yeasts (Candida, Pityrosporum, Torulopsis, Cryptococcus), dimorphic fungi and Fungi; except for Entomophthora, it has weaker effects on Aspergillus, Schenckia, some Phaeochromocytaceae, and Mucor. The mechanism of action of ketoconazole is mainly to highly selectively interfere with the activity of fungal cytochrome P-450, thereby inhibiting the biosynthesis of ergosterol on the fungal cell membrane.

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65277-42-1 25
Clobetasol propionateIngredients

It is a potent external corticosteroid. It acts quickly and has a strong capillary contraction effect. Its anti-inflammatory effect is 112.5 times that of hydrocortisone, 2.3 times that of betamethasone sodium phosphate, and 18.7 times that of fluocinolone.

More
25122-46-7 27

Appearance

This product is a white or off-white cream with an emulsion base.

Indication

Used for tinea corporis, tinea manuum, tinea pedis, and tinea cruris

Usage and Dosage

For external use, apply directly to the affected area, twice a day.

Adverse Reactions

1 Local allergic reactions may occur occasionally, such as burning sensation, itching, tingling, etc. 2 Long-term use may cause skin atrophy, capillary dilation, pigmentation and secondary infection.

Precautions

1. It is contraindicated for people with viral infections such as herpes and chickenpox. 2. It is contraindicated for pregnant and lactating women.

Special Population Medication

Precautions for children: Use with caution in infants and children. Precautions for pregnancy and lactation: (1) Pregnant women should use with caution after weighing the pros and cons. Long-term, large-area or large-scale use of this product is prohibited. (2) Lactating women should use with caution after weighing the pros and cons. Precautions for the elderly: Not yet clear.

Drug Interactions

Not yet clear.

Storage

seal

Packaging Specification

Each gram contains 10 mg of ketoconazole and 0.5 mg of clobetasol propionate

Validity Period

24 months.

Manufacturer

Dihon Pharmaceutical Group Co., Ltd.

  • Founded in:

    1997-03-05
  • Address:

    No. 45, Keyi Road, High-tech Development Zone, Kunming, Yunnan Province
  • Tax NO.:

    91530000622604706W
  • Registered Funds:

    205.128205 yuan
  • Email:

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