Famotidine chewable tablets

This product is a histamine H2 receptor antagonist. It has an inhibitory effect on the secretion of gastric acid and pepsin. Patients with gastric and duodenal ulcers were given this product at a dose of 20 mg twice a day for 1 to 2 months, and it had no effect on the gastrin level in the blood. Normal people and patients with peptic ulcers were given this product at a dose of 20 mg twice a day for 4 weeks, and it had no effect on the levels of prolactin, gonadotropin and sex hormones in the blood.

The main ingredient of this product is famotidine. Its chemical name is 3-[[[2-[(diaminomethylene)amino]-4-thiazolyl]methyl]thio]-N-sulfamoylpropionamidine. Molecular formula: C8H15N7O2S3, molecular weight: 337.47.

This product is white tablets.

It is suitable for peptic ulcer (gastric and duodenal ulcer), acute gastric mucosal lesions, reflux esophagitis and gastrinoma.

Swallow after chewing. For peptic ulcer, take 20 mg (1 tablet) twice a day, after breakfast, dinner or before bedtime. One course of treatment is 4 to 6 weeks. The maintenance dose is halved after the ulcer heals. The dosage and course of treatment for reflux esophagitis should be based on the condition or follow the doctor's advice. The dose should be reduced for patients with renal insufficiency.

1. Circulatory system: Rarely, pulse rate increase, blood pressure rise and facial flushing may occur. 2. Digestive system: Rarely, liver function abnormalities such as elevated transaminases may occur. Rarely, abdominal distension, loss of appetite, constipation, diarrhea, soft stools, thirst, nausea and vomiting may occur. 3. Central nervous system: Rarely, headache, heaviness of the head and general fatigue may occur. 4. Allergic reaction: Rarely, rash and urticaria may occur. If allergic reaction occurs, the drug should be discontinued. 5. Others: Rarely, menstrual disorders, facial edema and tinnitus may occur.

It is contraindicated for people who are allergic to this product, patients with severe renal insufficiency, pregnant women and nursing mothers.

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not for use by pregnant and lactating women. Precautions for the elderly: Not yet clear.

1. This product does not bind to cytochrome P-450, does not interfere with the action of drug metabolizing enzymes, and does not affect the action of drugs metabolized through this system. Therefore, it does not affect the metabolism of drugs such as theophylline, phenytoin, warfarin and diazepam, nor does it affect the in vivo distribution of procainamide, etc. However, probenecid will inhibit the excretion of famotidine from the renal tubules. It has no anti-androgen activity. 2. This product should not be used in combination with antacids. Antacids containing aluminum hydroxide, magnesium, and dimethicone can reduce the bioavailability of famotidine, reduce its absorption and blood concentration.

Keep away from light and sealed. Valid for two years.

20mg

24 months

Guangzhou Pui's Pharmaceutical Factory Ltd.

• Founded in:

  1995-11-29

• Address:

  Room 403, 4th Floor, Building 2, No. 20, Guanda Road, Huangpu District, Guangzhou

• Tax NO.:

  91440101618438282F

• Registered Funds:

  $1.75 million

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