Omeprazole
Function and Efficacy
Proton pump inhibitor. This product is a fat-soluble weakly alkaline drug that is easily concentrated in an acidic environment. Therefore, after oral administration, it can be specifically distributed in the secretory tubules of the gastric mucosal parietal cells and converted into the active form of sulfenamide in this high-acid environment. It then irreversibly combines with the sulfhydryl group of the H,K-ATPase (also known as the proton pump) in the secretory membrane of the parietal cells through a disulfide bond to form a complex of sulfenamide and the proton pump, thereby inhibiting the activity of the enzyme and blocking the final step of gastric acid secretion. Therefore, this product has a strong and lasting inhibitory effect on gastric acid secretion caused by various reasons.
Ingredients
Omeprazole
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| OmeprazoleIngredients |
Proton pump inhibitor. This product is a fat-soluble weakly alkaline drug that is easily concentrated in an acidic environment. Therefore, after oral administration, it can be specifically distributed in the secretory tubules of the gastric mucosal parietal cells and converted into the active form of sulfenamide in this high-acid environment. It then irreversibly combines with the sulfhydryl group of the H,K-ATPase (also known as the proton pump) in the secretory membrane of the parietal cells through a disulfide bond to form a complex of sulfenamide and the proton pump, thereby inhibiting the activity of the enzyme and blocking the final step of gastric acid secretion. Therefore, this product has a strong and lasting inhibitory effect on gastric acid secretion caused by various reasons. More |
73590-58-6 | 83 |
Indication
It is suitable for gastric ulcer, duodenal ulcer, stress ulcer, reflux esophagitis and Zollinger-Ellison syndrome (gastrinoma).
Usage and Dosage
40 mg at a time, 1 to 2 times a day. Before use, inject 10 ml of special solvent into the vial of freeze-dried powder. Do not use other solvents to dissolve it. This product must be used within 2 hours after dissolution, and the push injection time should not be less than 20 minutes.
Adverse Reactions
Transient mild nausea, diarrhea, abdominal pain, paresthesia, dizziness or headache, etc., but will not affect treatment.
Precautions
1. It is forbidden for those who are allergic to this product, and should be used with caution by those with allergic constitution; 2. It should be used with caution by pregnant and lactating women; 3. It is forbidden for infants and young children.
Special Population Medication
Precautions for children: Forbidden for infants and young children. Precautions for pregnancy and lactation: Use with caution for pregnant and lactating women.
Drug Interactions
This product can delay the elimination of drugs metabolized by the liver in the body, such as diazepam, phenytoin sodium, warfarin, nifedipine, etc. When this product is used together with the above-mentioned drugs, the dosage of the latter should be reduced.
Storage
Sealed, store in a cool, dry place.
Packaging Specification
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