Domperidone Tablets

This product acts directly on the gastrointestinal wall, increasing gastrointestinal motility and tension, promoting gastric emptying, increasing gastric antrum and duodenal motility, coordinating pyloric contraction, and also enhancing esophageal motility and the tension of the lower esophageal sphincter, inhibiting nausea and vomiting. This product is not easy to pass through the blood-brain barrier.

Domperidone. Chemical name: 5_-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one.

This product is white tablets

Used for indigestion, abdominal distension, belching, nausea, vomiting, and abdominal pain.

Oral administration: Adults take 1 tablet at a time, 3 times a day, 15 to 30 minutes before meals.

1. Occasionally mild abdominal cramps, dry mouth, rash, headache, diarrhea, nervousness, fatigue, drowsiness, dizziness, etc. 2. Sometimes it leads to increased serum prolactin levels, galactorrhea, and feminization of male breasts, but it returns to normal after stopping the drug.

It is contraindicated for patients with pheochromocytoma, breast cancer, mechanical intestinal obstruction, gastrointestinal bleeding, etc.

Precautions for children: Rare neurological side effects in infants and young children. Because the metabolism and cell barrier functions of infants are not fully developed in the first few months after birth, the incidence of neurological side effects is higher than that of children. Therefore, it is recommended that the dosage for newborns, infants and young children should be accurately formulated and strictly followed. Drug overdose may cause neurological side effects, but other reasons should also be considered. Precautions for pregnancy and lactation: Pregnant women: There is limited experience with this product for pregnant women. Its potential harm to humans is not clear. However, in a study conducted on rats, domperidone showed reproductive toxicity at a higher dose that was toxic to the mother (40 times the recommended human dose). Therefore, for pregnant women, this product should be used with caution only after weighing the pros and cons. Lactation: The concentration of domperidone in the breast milk of lactating women is 10-50% of its corresponding plasma concentration, but it will not exceed 10ng/ml in breast milk. When lactating women take this product at the maximum recommended dose, the total amount of domperidone in breast milk is less than 7ug/day, and it is not known whether it will cause harm to newborns. Therefore, breastfeeding women are advised not to breastfeed while taking this product. Elderly precautions: Elderly patients use the same medication as adults.

1. It should not be used together with azole antifungal drugs such as ketoconazole and itraconazole, macrolide antibiotics such as erythromycin, HIV protease inhibitors and nefazodone. 2. Anticholinergic drugs such as tamoxifen, propantheline bromide, anisodamine, belladonna tablets, etc. will weaken the effect of this product and should not be taken with this product. 3. Antacids and drugs that inhibit gastric acid secretion can reduce the bioavailability of this product and should not be taken with this product. 4. If used with other drugs at the same time, drug interactions may occur. Please consult a doctor or pharmacist for details.

Keep away from light and store in sealed container.

10mg

12 months

Xiuzheng Pharmaceutical Group Changchun High Technology Pharmaceutical Co., Ltd.

• Founded in:

  2002-06-03

• Address:

  No. 1239, Shunda Road, High-tech Development Zone, Changchun City

• Tax NO.:

  91220000737039938H

• Registered Funds:

  100 million yuan

• Email:

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