Fenbufen Tablets
Function and Efficacy
This product is a long-acting non-steroidal anti-inflammatory drug. After entering the body, it is metabolized into diphenyl ethyl ester, which has the activity of inhibiting cyclooxygenase, reducing the synthesis of prostaglandins and taking effect. Animal experiments show that the anti-inflammatory and analgesic effect of this product is weaker than indomethacin, but stronger than aspirin. Acute toxicity test results: the oral LD50 of rats is 200-720 mg/kg, and the intraperitoneal injection LD50 is 265-575 mg/kg; the oral LD50 of mice is 795-1673 mg/kg, and the intraperitoneal injection LD50 is 506-811 mg/kg.
Ingredients
Fenbufen
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| FenbufenIngredients |
This product is a long-acting non-steroidal anti-inflammatory drug. After entering the body, it is metabolized into diphenyl ethyl ester, which inhibits the activity of cyclooxygenase and reduces the synthesis of prostaglandins. Animal experiments show that the anti-inflammatory and analgesic effects of this product are weaker than indomethacin, but stronger than aspirin. More |
36330-85-5 | 8 |
Appearance
This product is white or off-white tablets.
Indication
It is used to treat rheumatoid arthritis, rheumatic arthritis, osteoarthritis, spondyloarthropathies, and gouty arthritis. It can also be used for toothache, postoperative pain, and traumatic pain.
Usage and Dosage
Oral (1) Usual dosage for adults: 0.6 g per day, taken once or twice. The total daily dosage for adults should not exceed 1.0 g. (2) Usual dosage for children: Not yet established.
Adverse Reactions
The adverse reactions of this product are mainly gastrointestinal reactions, manifested as stomach pain, burning sensation in the stomach, nausea, and a few serious adverse reactions include gastric ulcer, bleeding, and even perforation. Dizziness, rash, mild decrease in white blood cell count, and mild increase in serum transferase are less common.
Precautions
1) Patients who are allergic to this product are contraindicated. (2) Patients with peptic ulcer, severe liver and kidney damage, or aspirin-induced asthma are contraindicated.
Special Population Medication
Precautions for children: follow doctor's advice. Precautions for pregnancy and lactation: follow doctor's advice. Precautions for the elderly: Elderly patients should pay attention to renal toxicity due to decreased renal function.
Drug Interactions
Not yet clear.
Storage
Keep away from light and store in sealed container.
Packaging Specification
0.15g
Validity Period
36 months
Manufacturer
Xiuzheng Pharmaceutical Group Changchun High Technology Pharmaceutical Co., Ltd.
-
Founded in:
2002-06-03 -
Address:
No. 1239, Shunda Road, High-tech Development Zone, Changchun City -
Tax NO.:
91220000737039938H -
Registered Funds:
100 million yuan -
Email: