Omeprazole enteric-coated capsules

Proton pump inhibitor. This product is a fat-soluble weak alkaline drug that is easily concentrated in an acidic environment. Therefore, after oral administration, it can be specifically distributed in the secretory tubules of the gastric mucosal parietal cells and converted into the active form of sulfenamide in this high-acid environment. It then irreversibly combines with the sulfhydryl group of the H, K-ATPase (also known as the proton pump) in the secretory membrane of the parietal cells through a disulfide bond to form a complex of sulfenamide and the proton pump, thereby inhibiting the activity of the enzyme and blocking the final step of gastric acid secretion. Therefore, this product has a strong and lasting inhibitory effect on gastric acid secretion caused by various reasons.

The main ingredient of this product is omeprazole. Its chemical name is 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)-methyl]-sulfinyl]-1H-benzimidazole.

This product is a capsule containing small particles in off-white enteric casing.

It is indicated for gastric ulcer, duodenal ulcer, stress ulcer, reflux esophagitis and Zollinger-Ellison syndrome (gastrinoma).

Oral administration, do not chew. 1 Peptic ulcer: 20 mg once, 1-2 times a day. Swallow in the morning or once in the morning and evening. The treatment course for gastric ulcer is usually 4-8 weeks, and the treatment course for duodenal ulcer is usually 2-4 weeks. 2 Reflux esophagitis: 20-60 mg once, 1-2 times a day. Swallow in the morning or once in the morning and evening. The treatment course is usually 4-8 weeks. 3 Zollinger-Ellison syndrome: 60 mg once, once a day. The total daily dose can be adjusted to 20-120 mg according to the condition. If the total daily dose exceeds 80 mg, it should be taken in two doses.

This product is well tolerated. Common adverse reactions include diarrhea, headache, nausea, abdominal pain, flatulence and constipation. Occasionally, serum aminotransferase (ALT, AST) increases, rash, dizziness, drowsiness, insomnia, etc. are seen. These adverse reactions are usually mild and disappear automatically. In some cases, gastric mucosal cell hyperplasia and atrophic gastritis may occur with long-term treatment.

It is contraindicated for patients who are allergic to this product or have severe renal insufficiency.

Precautions for children: It is forbidden for infants and young children. Precautions for pregnancy and lactation: Although this product has no teratogenic effect in animal experiments, it should generally not be used by pregnant women, and should also be used with caution for lactating women. Precautions for the elderly: It is not clear yet.

This product can delay the elimination of drugs metabolized by the liver in the body, such as diazepam, phenytoin sodium, warfarin, nifedipine, etc. When this product is used together with the above-mentioned drugs, the dosage of the latter should be reduced.

Keep away from light, tightly closed and in a dry place.

20mg

24 months.

Xiuzheng Pharmaceutical Group Changchun High Technology Pharmaceutical Co., Ltd.

• Founded in:

  2002-06-03

• Address:

  No. 1239, Shunda Road, High-tech Development Zone, Changchun City

• Tax NO.:

  91220000737039938H

• Registered Funds:

  100 million yuan

• Email:

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