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Cilostazol Tablets

Function and Efficacy

The mechanism of action of this product in improving intermittent thromboembolism symptoms is not yet fully understood. This product and its metabolites are cyclic adenosine monophosphate (cAMP) phosphodiesterase III inhibitors (PDEIII inhibitors), which can reduce the degradation of cAMP by inhibiting the activity of phosphodiesterase, thereby increasing the cAMP level in platelets and blood vessels, inhibiting platelet aggregation and vasodilation.

Ingredients

The main ingredient of this product is cilostazol, and its chemical name is: 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolone

Name Description Content CAS NO. Manufacturer
CilostazolIngredients

This product and its metabolites are cyclic adenosine monophosphate (cAMP) phosphodiesterase III inhibitors (PDEIII inhibitors), which can reduce the degradation of cAMP by inhibiting the activity of phosphodiesterase, thereby increasing the cAMP level in platelets and blood vessels, inhibiting platelet aggregation and vasodilation.

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73963-72-1 29

Appearance

This product is white or off-white tablets.

Indication

Improve symptoms such as chronic ulcers, pain, chills and intermittent claudication caused by chronic arteriosclerosis obliterans.

Usage and Dosage

Oral administration: 100 mg at a time (2 50 mg tablets or 1 100 mg tablet), 2 times a day. The dosage can be increased or decreased according to the condition.

Adverse Reactions

1 Systemic adverse reactions: abdominal pain, back pain, headache, infection, edema. 2 Circulatory system: occasional palpitations, rapid pulse, fever, dizziness, hypotension. 3 Digestive system: occasional stomach discomfort, upper abdominal pain, abdominal distension, loss of appetite, nausea, vomiting, soft stools, diarrhea. 4 Allergic reactions: occasional rash, eruptions, urticaria, itching. 5 Nervous system: occasional headache, heavy head, dizziness, vertigo, insomnia, numbness, occasional drowsiness, fatigue. 6 Liver: occasional increase in AST, ALT, LDH values. 7 Kidney: occasional increase in BUN, creatine, uric acid values

Precautions

1. Patients who are allergic to any component of this drug. 2. Patients with grade 3-4 congestive heart failure. 3. Patients with bleeding such as hemophilia, capillary fragility, upper gastrointestinal bleeding, hemoptysis, etc. 4. Women who are pregnant or may become pregnant.

Special Population Medication

Precautions for children: The safety of the drug for infants and young children has not been established. Precautions for pregnancy and lactation: It is contraindicated for women who are pregnant or may become pregnant. Precautions for the elderly: Generally speaking, the physiological functions of elderly patients are low, so attention should be paid to reducing the dosage, etc.

Drug Interactions

Prostaglandin E1 works synergistically with this product to increase intracellular cyclic guanosine-phosphate and enhance therapeutic efficacy.

Storage

Store in airtight container at room temperature. Valid for 24 months.

Packaging Specification

50mg

Validity Period

24 months

Manufacturer

Guilin Pharmaceutical Co., Ltd.

  • Founded in:

    2001-06-22
  • Address:

    No. 43, Qilidian Road, Guilin
  • Tax NO.:

    91450300729742527H
  • Registered Funds:

    285.0303 million yuan
  • Website:

  • Email:

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