Doxapram Hydrochloride Injection
Function and Efficacy
This product is a respiratory stimulant. In small doses, it reflexively excites the respiratory center through the carotid body chemoreceptors. In large doses, it directly excites the medullary respiratory center, increasing the tidal volume and increasing the respiratory rate to a limited extent. Large doses excite the spinal cord and brainstem, but seem to have no effect on the cerebral cortex. When patients with obstructive pulmonary disease have acute ventilation insufficiency, the use of this drug can improve tidal volume, blood carbon dioxide partial pressure, and oxygen saturation.
Ingredients
Doxapram hydrochloride
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Doxapram hydrochloride monohydrateIngredients |
This product is a respiratory stimulant. In small doses, it reflexively excites the respiratory center through the carotid body chemoreceptors. In large doses, it directly excites the medullary respiratory center, increasing the tidal volume and increasing the respiratory rate to a limited extent. Large doses excite the spinal cord and brainstem, but seem to have no effect on the cerebral cortex. When patients with obstructive pulmonary disease have acute ventilation insufficiency, the use of this drug can improve tidal volume, blood carbon dioxide partial pressure, and oxygen saturation. More |
7081-53-0 | 8 |
Appearance
This product is a colorless clear liquid
Indication
Usage and Dosage
Intravenous injection: 0.5-1.0 mg/kg per time, not exceeding 1.5 mg/kg. If repeated administration is required, at least 5 minutes interval should be maintained. The hourly dosage should not exceed 300 mg. Use with caution in children under 12 years old.
Adverse Reactions
Headache, weakness, nausea, vomiting, sweating, feeling very hot, diarrhea, and urinary retention.
Precautions
Patients with convulsions, epilepsy, severe hypertension, pheochromocytoma, hyperthyroidism, coronary heart disease, intracranial hypertension, and severe lung disease.
Drug Interactions
1. This product can promote the release of catecholamines. It can only be used 10 to 20 minutes after general anesthetics such as halothane and isoflurane are discontinued. 2. This product can be used in combination with caffeine, methylphenidate, pemoline, adrenergic receptor agonists, etc., which may cause tension, excitement, insomnia, and even convulsions or arrhythmias. 3. This product can significantly increase blood pressure when used in combination with monoamine oxidase inhibitors such as procarbazine and pressor drugs.
Storage
Keep away from light and store in a sealed container.
Packaging Specification
5ml:0.1g
Manufacturer
YANGTZE River Pharmaceutical Group Nanjing Pharmaceutical. Co., Ltd.
-
Founded in:
2001-01-16 -
Address:
No. 9 Xianlin Avenue, Qixia District, Nanjing -
Tax NO.:
91320192726063334T -
Registered Funds:
50 million yuan -
Website:
-
Email: