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Pilocarpine Nitrate Injection

Function and Efficacy

This product has a direct excitatory effect on smooth muscles and various glands, especially on salivary glands and sweat glands. It directly stimulates the M cholinergic receptors, causing the iris sphincter to contract, the pupil to shrink, and the ciliary muscle to contract, resulting in a decrease in the resistance to regulating the discharge of aqueous humor, thus reducing the intraocular pressure of glaucoma.

Ingredients

The main ingredient of this product is pilocarpine nitrate.

Name Description Content CAS NO. Manufacturer
Pilocarpine nitrateIngredients

It has a direct excitatory effect on smooth muscles and various glands, especially on salivary glands and sweat glands. It directly stimulates the M cholinergic receptors, causing the iris sphincter to contract, the pupil to shrink, and the ciliary muscle to contract, resulting in a decrease in the resistance to the discharge of aqueous humor, thus reducing the intraocular pressure of glaucoma.

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148-72-1 7

Appearance

This product is a colorless clear liquid.

Indication

1. For open-angle glaucoma, acute and chronic angle-closure glaucoma, and secondary angle-closure glaucoma. 2. For miosis during cataract intraocular lens implantation. 3. For symptomatic treatment of atropine-type drug poisoning.

Usage and Dosage

Subcutaneous injection: 2-10 mg at a time, diluted and injected into the anterior chamber during surgery or as directed by the doctor.

Adverse Reactions

Symptoms may include drooling, sweating, gastrointestinal discomfort, abdominal pain, etc.

Precautions

1. Patients with iridocyclitis and pupillary block glaucoma are contraindicated. 2. Patients who are allergic to this product are contraindicated.

Special Population Medication

Precautions during pregnancy and lactation: Safety is not yet certain, so use with caution.

Drug Interactions

1. This product has a synergistic effect when used in combination with beta-receptor blockers, carbonic anhydrase inhibitors, alpha- and beta-adrenergic receptor agonists or hypertonic dehydrating agents. 2. This product combined with laprostaglandin can reduce the amount of aqueous humor outflow through the uveal sclera and reduce the intraocular pressure lowering effect. 3. Combination with topical anticholinergics will interfere with the intraocular pressure lowering effect of this product. Combination with an appropriate amount of systemic anticholinergics usually does not affect the intraocular pressure lowering effect of this product because the concentration of systemic drugs reaching the eye is very low.

Storage

Keep away from light and store in a sealed container.

Packaging Specification

1ml:2mg

Validity Period

24 months

Manufacturer

Tianjin Pharmaceutical Heping (Tianjin) Pharmaceutical Co., Ltd.

  • Founded in:

    2010-11-12
  • Address:

    No. 221 Huanghai Road, Tianjin Development Zone
  • Tax NO.:

    91120116562691739J
  • Registered Funds:

    604.05 million yuan
  • Website:

  • Email:

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