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Triamcinolone acetonide econazole cream

Function and Efficacy

This product is an azole antifungal drug and a dechlorinated derivative of miconazole. This product has antibacterial effects on Candida, Chromatiaceae, Coccidioides, Histoplasma, Sporothrix, etc., and also has antibacterial activity against Trichophyton, etc. This product has poor effects on Aspergillus, Sporothrix Schenckii, some dark-colored spores, Mucor, etc. This product inhibits the biosynthesis of ergosterol, the main steroid of fungal cell membrane, by interfering with the activity of cytochrome P-450, damaging the fungal cell membrane and changing its permeability, resulting in leakage of important intracellular substances. This product can inhibit the biosynthesis of triglycerides and phospholipids of fungi, inhibit the activity of oxidases and peroxidases, cause the accumulation of hydrogen peroxide in cells, and lead to cell submicrostructure degeneration and cell necrosis. For Candida albicans, it can inhibit the process of transformation from spores to invasive hyphae.

Ingredients

1% Econazole Nitrate 0.1% Triamcinolone Acetonide

Name Description Content CAS NO. Manufacturer
Econazole nitrateIngredients

This product is an azole antifungal drug, which has antibacterial effects on Candida, Chromatiaceae, Coccidioides, Histoplasma, Sporothrix, etc., and also has antibacterial activity against Trichophyton, etc. It interferes with the activity of cytochrome P-450, inhibits the biosynthesis of ergosterol, the main steroid of fungal cell membrane, damages the fungal cell membrane and changes its permeability, leading to leakage of important intracellular substances. It can inhibit the biosynthesis of triglycerides and phospholipids of fungi, inhibit the activity of oxidase and peroxidase, cause the accumulation of hydrogen peroxide in cells, and lead to cell submicrostructure degeneration and cell necrosis. For Candida albicans, it can inhibit the process of transformation from spores to invasive hyphae.

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68797-31-9 18
Triamcinolone acetonideIngredients

This product is an azole antifungal drug and a dechlorinated derivative of miconazole. This product has antibacterial effects on Candida, Chromatiaceae, Coccidioides, Histoplasma, Sporothrix, etc., and also has antibacterial activity against Trichophyton, etc. This product has poor effects on Aspergillus, Sporothrix Schenckii, some dark-colored spores, Mucor, etc. This product inhibits the biosynthesis of ergosterol, the main steroid of fungal cell membrane, by interfering with the activity of cytochrome P-450, damaging the fungal cell membrane and changing its permeability, resulting in leakage of important intracellular substances. This product can inhibit the biosynthesis of triglycerides and phospholipids of fungi, inhibit the activity of oxidases and peroxidases, cause the accumulation of hydrogen peroxide in cells, and lead to cell submicrostructure degeneration and cell necrosis. For Candida albicans, it can inhibit the process of transformation from spores to invasive hyphae.

More
76-25-5 27

Appearance

This product is a milky white ointment with an emulsion base.

Indication

1. Dermatitis and eczema accompanied by fungal infection or with a tendency to fungal infection; 2. Inflammatory skin fungal diseases caused by dermatophytes, yeasts and molds, such as tinea manuum, tinea corporis, tinea cruris and tinea versicolor; 3. Diaper dermatitis; 4. Candidal angular cheilitis; 5. Paronychia; 6. Mixed skin infections caused by fungi and bacteria.

Usage and Dosage

For topical use. Apply an appropriate amount of this product to the affected area once a day in the morning and evening. For the treatment of dermatitis and eczema, the course of treatment is 2-4 weeks. The treatment of inflammatory fungal diseases should continue until the inflammatory reaction subsides, and the course of treatment should not exceed 4 weeks.

Adverse Reactions

Occasionally, local allergic reactions may occur, such as burning sensation, itching, tingling, etc. Long-term use may cause skin atrophy, capillary dilation, pigmentation, and secondary infection.

Precautions

It is contraindicated for people with skin tuberculosis, syphilis or viral infections (such as herpes, vaccinia, chickenpox).

Special Population Medication

Precautions for children: follow doctor's advice. Precautions for pregnancy and lactation: follow doctor's advice. Precautions for the elderly: follow doctor's advice.

Drug Interactions

Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.

Storage

Keep tightly closed in a cool place.

Packaging Specification

Each gram contains 1 mg of triamcinolone acetonide and 10 mg of econazole nitrate

Validity Period

24 months

Manufacturer

TC Pharmaceuticals (Jiangsu) Co., Ltd.

  • Founded in:

    1994-12-12
  • Address:

    No. 191, Jinyang West Road, Lujia Town, Kunshan City, Jiangsu Province
  • Tax NO.:

    91320583608280290E
  • Registered Funds:

    126.271311 yuan
  • Website:

  • Email:

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