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Medium/long chain fat emulsion injection (C6~24)

Function and Efficacy

Through parenteral nutrition, long-chain triglycerides (LCT) and rapidly convertible medium-chain triglycerides (MCT) meet the body's energy needs, among which long-chain triglycerides (LCT) can also guarantee the need for essential fatty acids. Fatty acids are the main energy source for the human body, and fatty acid oxidation is an important source of energy in the human body. When the oxygen supply is sufficient, fatty acids can be decomposed into CO2 and H2O in the body and release a large amount of energy, which is used by the body in the form of ATP. Except for brain tissue, most tissues can oxidize fatty acids, especially the liver and muscles are the most active. Certain unsaturated fatty acids cannot be synthesized by the body itself and need to be taken from vegetable oils. They are indispensable nutrients for the body, so they are called essential fatty acids. They are also physiologically active substances such as prostaglandins, thromboxanes and leukotrienes.

Ingredients

This product is a compound preparation, its components are: purified soybean oil, medium chain triglycerides, refined egg yolk lecithin, glycerol

Name Description Content CAS NO. Manufacturer
Egg phospholipidsExcipients

Through parenteral nutrition, long-chain triglycerides (LCT) and rapidly convertible medium-chain triglycerides (MCT) meet the body's energy needs, among which long-chain triglycerides (LCT) can also guarantee the need for essential fatty acids. Fatty acids are the main energy source for the human body, and fatty acid oxidation is an important source of energy in the human body. When the oxygen supply is sufficient, fatty acids can be decomposed into CO2 and H2O in the body and release a large amount of energy, which is used by the body in the form of ATP. Except for brain tissue, most tissues can oxidize fatty acids, especially the liver and muscles are the most active. Certain unsaturated fatty acids cannot be synthesized by the body itself and need to be taken from vegetable oils. They are indispensable nutrients for the body, so they are called essential fatty acids. They are also physiologically active substances such as prostaglandins, thromboxanes and leukotrienes.

More
93685-90-6 26
GlycerolExcipients

Through parenteral nutrition, long-chain triglycerides (LCT) and rapidly convertible medium-chain triglycerides (MCT) meet the body's energy needs, among which long-chain triglycerides (LCT) can also guarantee the need for essential fatty acids. Fatty acids are the main energy source for the human body, and fatty acid oxidation is an important source of energy in the human body. When the oxygen supply is sufficient, fatty acids can be decomposed into CO2 and H2O in the body and release a large amount of energy, which is used by the body in the form of ATP. Except for brain tissue, most tissues can oxidize fatty acids, especially the liver and muscles are the most active. Certain unsaturated fatty acids cannot be synthesized by the body itself and need to be taken from vegetable oils. They are indispensable nutrients for the body, so they are called essential fatty acids. They are also physiologically active substances such as prostaglandins, thromboxanes and leukotrienes.

More
56-81-5 61

Appearance

This product is a white milky liquid.

Indication

For use in patients who require parenteral nutrition and/or have essential fatty acid deficiency.

Usage and Dosage

Intravenous drip. Unless otherwise specified or based on energy needs. Recommended dose: Daily intravenous drip of 10% 10-20 ml/kg of body weight, or 20% 5-10 ml/kg of body weight, equivalent to 1-2 g (2 g is the maximum recommended dose) of fat/kg. Infusion rate: The maximum rate is intravenous drip of 10% 1.25 ml/kg of body weight or 20% 0.625 ml/kg of body weight per hour (equivalent to 0.125 g of fat/kg). When starting to use this product for parenteral nutrition therapy, it is recommended to use a slower rate, that is, drip 0.05 g of fat/kg per hour. This product can be infused alone or prepared into an "all-in-one" nutrient mixture for infusion. Only in compatible

Adverse Reactions

Possible early adverse reactions after using this product are: - Mild increase in body temperature - Fever, cold feeling - Shivering - Abnormal heat sensation (flushing) or cyanosis - Loss of appetite, nausea, vomiting - Difficulty breathing - Headache, back pain, bone pain, chest pain, waist pain - Abnormal penile erection (rare) - Increased or decreased blood pressure (hypertension, hypotension) - Allergic reaction (e.g. anaphylactic-like reaction, rash) If these adverse reactions occur, or the serum triglyceride concentration is higher than 3mmol/L during fat emulsion infusion, the infusion should be stopped and, if necessary, the dose should be reduced before infusion. If there is significant reactive blood sugar

Precautions

Severe coagulation disorders, shock and collapse, pregnancy, acute thromboembolism, severe sepsis with acidosis and hypoxia, fat embolism, acute myocardial infarction and stroke, ketoacidosis coma and diabetic pre-coma. When triglyceride accumulation occurs during infusion, the following will also be contraindicated: lipid metabolism disorders, liver dysfunction, renal dysfunction, reticuloendothelial system disorders, acute hemorrhagic necrotizing pancreatitis. General contraindications to parenteral nutrition: acidosis caused by various reasons, untreated water and electrolyte metabolism disorders (hypotonic dehydration, hypokalemia, water retention), metabolic instability, and intrahepatic cholestasis.

Drug Interactions

No interactions with other medicinal products have been found.

Storage

Below 25℃, do not freeze. The validity period is tentatively set at 24 months.

Packaging Specification

250 ml: 25g soybean oil, 25g medium chain triglycerides, 3g lecithin

Manufacturer

Feisenyuskabi Huarui Pharmaceutical Co., Ltd.

  • Founded in:

    1982-11-24
  • Address:

    No. 16, Mashanbeizha Road, Binhu District, Wuxi City, Jiangsu Province
  • Tax NO.:

    91320200607912321D
  • Registered Funds:

    $27.9 million
  • Website:

  • Email:

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