Procaterol Hydrochloride Oral Solution

1. Bronchodilator effect: From the effect of inhibiting the increase of airway resistance in dogs, cats and guinea pigs, the bronchodilator effect of Procaterol hydrochloride is the same as or stronger than that of isoproterenol, and stronger than that of salbutamol and metaproterenol. 2. Duration of bronchodilator effect: The duration of bronchodilator effect of Procaterol hydrochloride was studied in dogs, cats and guinea pigs, and it was found that it was longer than that of isoproterenol, thiophene, metaproterenol and salbutamol. 3. Selectivity for beta2-receptors: When studying the selectivity of Procaterol hydrochloride for beta2 receptors in the cardiovascular and respiratory systems using dogs, cats and guinea pigs, it was found that its organ selectivity was better than that of isoproterenol, thiophene, metaproterenol and salbutamol. 4. Anti-allergic effect: The study used the increase in reactive airway resistance in guinea pigs or rats, PCA reaction and histamine release in the lungs, skin reaction in adult bronchial asthma patients, and inhibition of asthma induced by inhaled allergens as indicators and found that the anti-allergic effect of Procaterol hydrochloride was stronger than that of isoproterenol, metaproterenol and salbutamol. 5. Effect on the respiratory secretion system: Procaterol hydrochloride causes hyperactivity of the respiratory cilia in pigeons. 6. Inhibitory effect on exercise-induced asthma attacks: Procaterol hydrochloride can inhibit exercise-induced asthma. 7. Effect on airway hyperresponsiveness: Procaterol hydrochloride can inhibit airway hyperresponsiveness in dogs induced by influenza C virus inoculation. 8. Effect on increased vascular permeability: Procaterol hydrochloride has an inhibitory effect on the increased vascular permeability and edema formation in the subcutaneous air sacs on the back of rats caused by various inflammatory substances, which is basically the same as isoproterenol. In addition, it has an inhibitory effect on the formation of pulmonary edema in guinea pigs caused by inhaled histamine, and this effect is stronger than salbutamol. 9. Effect on cough Procaterol hydrochloride can inhibit cough in patients with acute bronchitis induced by inhaled substance P.

The main ingredient of this product is Procaterol Hydrochloride.

This product is a colorless, clear, slightly viscous liquid with an orange aroma and sweet taste.

This product relieves symptoms such as dyspnea caused by obstructive respiratory disorders in the following diseases: bronchial asthma, chronic bronchitis, acute bronchitis, and asthmatic bronchitis.

Usually, adults: take orally once a day before bed or twice a day in the morning and evening before bed, 50ug each time (equivalent to 10ml of oral solution); children over 6 years old: take orally once a day before bed or twice a day in the morning and evening before bed, 25ug each time (equivalent to 5ml of oral solution); infants under 6 years old: take orally twice a day in the morning and evening before bed or 3 times a day in the morning, noon and evening before bed, 1.25ug/kg each time (equivalent to 0.25ml/kg of oral solution). In addition, the dosage can be increased or decreased appropriately according to age and symptoms. Usually, the standard dosage for children under 6 years old is as follows: under 1 year old: 10-15ug/day (equivalent to 2-3ml of oral solution); 1-3 years old: 15-20ug/day (equivalent to 3-4ml of oral solution);

Occasionally, you may experience general fatigue, dry mouth, nasal congestion, stomach discomfort, dizziness or tinnitus. Sometimes you may experience rash, muscle tremors, headache, nausea, vomiting, etc. (See the inner package insert for details)

1. Patients who are currently taking catecholamine preparations (epinephrine, isoproterenol) are contraindicated. 2. Patients with a history of allergy to the ingredients of this product are contraindicated.

Precautions for children: The safety of administration to premature infants and newborns has not been established (no experience). Precautions for pregnancy and lactation: Administration to pregnant and lactating women 1. Since the safety of administration during pregnancy has not been established, it can only be administered to pregnant women or women who may become pregnant when the therapeutic benefits outweigh the risks. 2. Transfer to animal (rat) milk has been reported, so breastfeeding should be avoided during administration of this product. Precautions for the elderly: In general, due to the low physiological function of elderly patients, attention should be paid to reducing the dosage, etc.

1. Do not use with catecholamine preparations (epinephrine, isoproterenol) [cardiac arrhythmia, sometimes there is a risk of cardiac arrest]. 2. When using with xanthine derivatives (sometimes it may enhance the side effects such as hypokalemia), steroid preparations and diuretics (sometimes it may enhance the hypokalemia effect).

seal.

30ml:0.15mg(0.0005%)

Year 2

Jiangsu Hanchen Pharmaceutical Co., Ltd.

• Founded in:

  2005-05-18

• Address:

  No. 188, Santiaoqiao Road, Yuelai Industrial Zone, Haimen District, Nantong City, Jiangsu Province

• Tax NO.:

  91320684773231329P

• Registered Funds:

  5.4572797 yuan

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