Flunarizine Hydrochloride Tablets

This product is a calcium channel blocker. It can prevent cell damage caused by pathological calcium overload in cells due to ischemia and other reasons. This product has the following effects: 1. It relieves vasospasm and has a lasting inhibitory effect on persistent vasospasm caused by vasoconstrictor substances, especially on the basilar artery and internal carotid artery. Its effect is 15 times stronger than that of cerbrine; 2. It has vestibular inhibitory effect, which can increase the blood flow of cochlear arterioles and improve the circulation of vestibular organs; 3. It has anti-epileptic effect, which can block the pathological calcium overload of nerve cells and prevent paroxysmal depolarization and cell discharge, thereby avoiding epileptic seizures; 4. It protects the myocardium and significantly reduces ischemic myocardial damage; 5. Flunarizine also has the effect of improving renal function and can be used for chronic renal failure; in addition, this product also has anti-histamine effect.

Main ingredient: Flunarizine hydrochloride. Molecular formula: C26H26F2N2·2HCl Molecular weight: 477.42

This product is white tablets.

1. Insufficient blood supply to the brain, vertebral artery ischemia, cerebral thrombosis, etc. 2. Tinnitus, dizziness. 3. Prevention of migraine. 4. Auxiliary treatment of epilepsy.

Oral administration: 6-12 mg (1-2 tablets each time), once a day, before bedtime.

1. Adverse reactions of the central nervous system include: ① Drowsiness and fatigue are the most common; ② Depression may occur in long-term users, which is more common in female patients; ③ Extrapyramidal symptoms, manifested as involuntary movements, mandibular movement disorders, rigidity, etc. Most of them appear after 3 weeks of medication and disappear after stopping the medication. It is more likely to occur in the elderly; ④ A small number of patients may experience insomnia, anxiety and other symptoms. 2. Gastrointestinal symptoms are manifested as: burning sensation in the stomach, hyperappetite, increased food intake, and weight gain. 3. Others: A small number of patients may experience rash, dry mouth, galactorrhea, muscle aches and other symptoms. But most of them are transient and can be relieved by stopping the medication.

This drug is contraindicated in patients with a history of allergy to the drug, a history of depression, or acute cerebral hemorrhage.

Precautions for children: This product has not been tested and there is no reliable reference. Precautions for pregnancy and lactation: Animal tests show that this product has no harm to reproduction, embryonic development, pregnancy and perinatal period. There is no safety data for the use of this product during human pregnancy. Although there is no data on the secretion of this product in human milk, tests on lactating dogs show that flunarizine hydrochloride can be secreted in breast milk, and its concentration in breast milk is higher than that in blood, so women taking this product are advised not to breastfeed. Precautions for the elderly: Use with caution in elderly patients.

1. When used in combination with alcohol, hypnotics or sedatives, the sedative effect is aggravated. 2. When used in combination with phenytoin sodium and carbamazepine, the blood concentration of flunarizine can be reduced. 3. When flunarizine is used in combination with radiotherapy patients, it can increase the killing power of tumor cells. 4. On the basis of anti-epileptic drug treatment, the addition of flunarizine can improve the anti-epileptic effect.

Protect from light, seal tightly, and store in a cool and dry place.

5mg (calculated as flunarizine)

24 months

Changchun Haiwai Pharmaceutical Group Co., Ltd.

• Founded in:

  1999-05-06

• Address:

  No. 1 Overseas Street, Changchun City

• Tax NO.:

  91220101715314505M

• Registered Funds:

  9 million yuan

• Email:

  Log in to view