On ECHEMI
Home > Drugs > Benzalkonium bromide solution

Benzalkonium bromide solution

Function and Efficacy

This product is a cationic surfactant broad-spectrum bactericide that can change the permeability of bacterial cytoplasmic membranes, causing bacterial cytoplasmic substances to extravasate, hindering their metabolism and killing them. It has a strong effect on Gram-positive bacteria, but is ineffective against Pseudomonas aeruginosa, acid-fast bacilli and bacterial spores. It can quickly bind to proteins, and its effect is significantly reduced in the presence of blood, cotton, cellulose and organic matter. It is non-irritating to the skin at concentrations below 0.1%.

Ingredients

This product is a mixture of dimethylbenzyl ammonium bromide.

Appearance

This product is a colorless or light yellow clear liquid with a fragrant aroma and extremely bitter taste. Strong shaking will produce a lot of foam. It may become turbid or precipitate when exposed to low temperatures.

Indication

Used for skin disinfection, mucous membrane and wound disinfection, and surgical instrument disinfection before surgery.

Usage and Dosage

Use 0.01% solution to disinfect wounds, 0.1% solution to disinfect skin and mucous membranes, and soak hands in 0.05%-0.1% solution for 5 minutes before surgery; boil surgical instruments with 0.1% solution for 15 minutes and then soak for 30 minutes; use solutions below 0.005% for bladder and urethra lavage; and use 0.0025% solution as bladder retention solution.

Adverse Reactions

It has been reported to cause allergic conjunctivitis, visual impairment, contact dermatitis, and there have also been reports that 3% solution enema caused nausea, cold sweats and death a few minutes after use. There have also been cases of death when used as a vaginal wash, but the mortality rate has been significantly reduced.

Precautions

It is contraindicated for those who are allergic to this product.

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Use under the guidance of a doctor. Precautions for the elderly: Not yet clear.

Drug Interactions

This product is incompatible with soap and other cationic surfactants, citrates, iodides, nitrates, permanganates, salicylates, silver salts, tartrates, and alkaloids. It is also incompatible with aluminum, sodium fluorescein, hydrogen peroxide, kaolin, aqueous lanolin, and some sulfonamides.

Storage

Keep away from light and store in a sealed container.

Packaging Specification

5%

Validity Period

36 months

Manufacturer

Nanchang Baiyun Pharmaceutical Co., Ltd.

  • Founded in:

    1990-01-12
  • Address:

    Yangzizhou Forest Farm, Qingshan Lake District, Nanchang City, Jiangxi Province
  • Tax NO.:

    9136010015826142XA
  • Registered Funds:

    2 million yuan
  • Website:

  • Email:

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.