Sulfadiazine Ice Yellow Tablets
Function and Efficacy
Sulfadimethoxazole and trimethoprim (TMP) have synergistic antibacterial or bactericidal effects, because sulfa drugs act on dihydrofolate synthase, interfering with the first step of folic acid synthesis, while trimethoprim acts on the second step of folic acid anabolism, selectively inhibiting dihydrofolate reductase. Therefore, the combination of the two can double-block the folic acid metabolism of bacteria. The synergistic antibacterial effect of the two is enhanced compared to the use of a single drug, and the drug-resistant strains are reduced.
Ingredients
The main ingredients of this product are borneol, artificial bezoar, sulfamethoxazole and trimethoprim.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| BorneolIngredients |
Sulfadimethoxazole and trimethoprim (TMP) have synergistic antibacterial or bactericidal effects, because sulfa drugs act on dihydrofolate synthase, interfering with the first step of folic acid synthesis, while trimethoprim acts on the second step of folic acid anabolism, selectively inhibiting dihydrofolate reductase. Therefore, the combination of the two can double-block the folic acid metabolism of bacteria. The synergistic antibacterial effect of the two is enhanced compared to the use of a single drug, and the drug-resistant strains are reduced. More |
507-70-0 | 1 | |
| Atificial Cow-bezoarIngredients |
Sulfadimethoxazole and trimethoprim (TMP) have synergistic antibacterial or bactericidal effects, because sulfa drugs act on dihydrofolate synthase, interfering with the first step of folic acid synthesis, while trimethoprim acts on the second step of folic acid anabolism, selectively inhibiting dihydrofolate reductase. Therefore, the combination of the two can double-block the folic acid metabolism of bacteria. The synergistic antibacterial effect of the two is enhanced compared to the use of a single drug, and the drug-resistant strains are reduced. More |
1002-00-2 | 2 | |
| SulfamethoxazoleIngredients |
It acts on dihydrofolate synthase, interfering with the first step of folic acid synthesis; combined with trimethoprim, it can doubly block the bacterial folic acid metabolism, enhance the synergistic antibacterial effect, and reduce drug-resistant strains. More |
723-46-6 | 33 | |
| TrimethoprimIngredients |
Selectively inhibits dihydrofolate reductase and acts on the second step of folic acid anabolism; combined with sulfamethoxazole, it can double-block bacterial folic acid metabolism, enhance synergistic antibacterial effects, and reduce drug-resistant strains. More |
738-70-5 | 44 |
Appearance
This product is a green diamond-shaped film-coated tablet, which appears light orange-yellow when the film coating is removed.
Indication
Used for tonsillitis, bronchitis, enteritis, dysentery, urinary tract infection, etc.
Usage and Dosage
Oral administration. 1-2 tablets at a time, twice a day. Or as directed by your doctor.
Adverse Reactions
1. Adverse reactions of sulfamethoxazole: ⑴ Allergic reactions are more common, which may manifest as drug rash. In severe cases, exudative erythema multiforme, exfoliative dermatitis and bullous epidermolysis atrophic dermatitis may occur; there are also serum sickness-like reactions such as photosensitivity, drug fever, joint and muscle pain, fever, etc. Anaphylactic shock is occasionally seen. ⑵ Neutropenia or deficiency, thrombocytopenia and aplastic anemia. Patients may show sore throat, fever, pallor and bleeding tendency. ⑶ Hemolytic anemia and hemoglobinuria. This is easy to occur in patients who lack glucose-6-phosphate dehydrogenase after using sulfonamides, and is more common in newborns and children than in adults. ⑷ Hyperbilirubinemia and neonatal kernicterus. Because this product competes with bilirubin for protein binding sites, it can cause increased free bilirubin. Neonatal liver function
Precautions
1. It is contraindicated for patients with severe renal impairment; 2. It is contraindicated for patients who are allergic to sulfonamides; 3. It is contraindicated for patients with megaloblastic anemia; 4. It is contraindicated for infants under 2 months old; 5. It should be used with caution by pregnant women.
Special Population Medication
Precautions for children: It is forbidden for infants under 2 months old. Precautions for pregnancy and lactation: Pregnant women should use with caution. Precautions for the elderly: Elderly patients have an increased chance of serious adverse reactions when using sulfonamides. Severe rash, bone marrow suppression and thrombocytopenia are common serious adverse reactions in the elderly. Therefore, elderly patients should avoid using it. If there is an indication, the decision should be made after weighing the pros and cons.
Drug Interactions
Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Storage
seal.
Packaging Specification
Compound
Validity Period
24 months
Manufacturer
Guangdong Jiuming Pharmaceutical Co., Ltd.
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Founded in:
2001-10-16 -
Address:
Keji 1st Road, Heyuan Hi-Tech Development Zone -
Tax NO.:
914416007321770637 -
Registered Funds:
42.173913 million yuan -
Website:
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Email: