Aminophenol loratadine and pseudoephedrine sustained-release tablets

This product is a compound preparation composed of acetaminophen, loratadine and pseudoephedrine sulfate. Among them, acetaminophen is an oral acetanilide antipyretic analgesic, which may produce antipyretic and analgesic effects mainly by inhibiting the synthesis of prostaglandins. Loratadine is a long-acting tricyclic antihistamine that can relieve nasal or non-nasal symptoms of seasonal allergic rhinitis by selectively antagonizing peripheral H1 receptors. Pseudoephedrine sulfate is an adrenergic drug that can constrict nasal mucosal blood vessels and relieve symptoms of nasal congestion and runny nose.

This product is a compound preparation, its components are: acetaminophen, pseudoephedrine sulfate, and loratadine.

This product is white or off-white tablets.

Used to relieve symptoms such as sneezing, runny nose, nasal congestion, throat discomfort, fatigue, fever, muscle aches, headaches, etc. caused by colds and seasonal allergic rhinitis.

Oral administration: Adults and children over 12 years old take 1 to 2 tablets every 12 hours.

Loratadine: Common adverse reactions reported with loratadine include fatigue, headache, drowsiness, dry mouth, gastrointestinal disorders such as nausea and stomach pain, and allergic symptoms such as rash. During the marketing of loratadine tablets, hair loss, allergic reactions and liver dysfunction were rare. Pseudoephedrine sulfate: Patients who are particularly sensitive to sympathomimetics may have mild irritation reactions: nausea, headache, drowsiness, weakness, dizziness, tachycardia, palpitations, insomnia, nervousness, excitement, restlessness, and mydriasis have also been reported. In addition, the possibility of other adverse reactions related to sympathomimetics must be considered. Acetaminophen: The adverse reactions of acetaminophen at the recommended dose are generally weak. Hematological reactions and rashes have been reported. Long-term use can cause kidney toxicity.

This product is contraindicated for patients who are allergic to any ingredient of this product or adrenergic drugs; patients who are taking or have taken monoamine oxidase inhibitors within 14 days are contraindicated for this product; patients with angle-closure glaucoma, urinary retention, severe hypertension, severe coronary artery disease and hyperthyroidism are also contraindicated for this product.

Loratadine 1 Clinical trials have shown that taking ketoconazole, erythromycin or cimetidine at the same time will increase the blood concentration of loratadine, but there are no significant clinical symptoms (including electrocardiogram); 2 Unless a definitive drug interaction study is completed, other drugs known to have an inhibitory effect on liver metabolism should be taken with caution; 3 This product should be discontinued at least 48 hours before skin testing. Antihistamines and loratadine may inhibit or eliminate the symptoms of positive skin reactions.

Store in a sealed container at 2°C to 30°C, shielded from light. The shelf life is tentatively 24 months.

Each tablet contains 0.5g of acetaminophen, 60mg of pseudoephedrine sulfate and 2.5mg of loratadine

Tentative 24 months

Wuhan Weiao Pharmacauti Cal Co., Ltd.

• Founded in:

  1996-10-30

• Address:

  Wuhan University Science and Technology Park, Jiangxia Avenue, East Lake New Technology Development Zone, Wuhan

• Tax NO.:

  91420100616432784K

• Registered Funds:

  30 million yuan

• Website:

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• Email:

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