Potassium Sodium Hydrogen Citrate Granules

Pharmacology: Oral administration of levofloxacin increases urine pH and citrate excretion and reduces urine calcium concentration. This levofloxacin-induced change makes the salts in urine more susceptible to crystallization. The resulting reduction in calcium concentration reduces the saturation of urine with calcium salts that can form stones. The increase in pH increases the solubility of uric acid and cystine stones. Toxicology: The acute toxicity of oral levofloxacin is low, as shown by LD50 values of gram quantities of the drug fed to different species of animals. Signs of poisoning are generally due to electrolyte overload, and long-term toxicity studies in rats and dogs have shown no specific target organ toxicity at oral doses of up to 3000 mg/kg body weight. The increase in urine pH is attributed to the pharmacodynamic effects of the citrate complex. Animal experiments have shown that levofloxacin has no embryo- and teratogenic potential. levofloxacin is a physiological compound and its potential mutagenic or carcinogenic effects can be ignored.

Chemical name: Potassium sodium hydrogen citrate Chemical formula: K6Na6H3(C6H5O7)5 Molecular weight: 1321.06 Chemical name: Potassium sodium hydrogen citrate Molecular weight: K6Na6H3(C6H5O7)5

This product is light orange granules with aromatic odor and salty taste.

For dissolving uric acid stones and preventing the formation of new stones, as a maintenance treatment for cystine stones and cystinuria.

Unless otherwise specified, the daily dose is 4 bags (2.5g per bag, 10g granules in total), taken three times after meals. One bag each in the morning and at noon, and two bags in the evening. Granules can be taken with water. For other details, please refer to the instructions.

Occasionally mild gastrointestinal discomfort may occur.

Potassium sodium bicitrate should not be used in patients with acute or chronic renal failure or when sodium chloride is absolutely contraindicated. Potassium sodium bicitrate is also contraindicated in patients with severe acid-base imbalance (base metabolism) or chronic urinary tract urea-degrading bacterial infections.

Precautions for children: Not yet determined. Precautions for pregnancy and lactation: There is no evidence that there are any adverse effects of using potassium sodium hydrogen citrate granules during pregnancy and lactation. Precautions for the elderly: Not yet determined.

This medicine contains the colorant Orange S (E110), which may induce allergic reactions including asthma in susceptible individuals. Allergic reactions are more likely to occur in patients who have taken 2-acetylbenzoic acid (acetylsalicylic acid).

Sealed, store in a dry place.

2.5g

60 months

Wuhan Weiao Pharmacauti Cal Co., Ltd.

• Founded in:

  1996-10-30

• Address:

  Wuhan University Science and Technology Park, Jiangxia Avenue, East Lake New Technology Development Zone, Wuhan

• Tax NO.:

  91420100616432784K

• Registered Funds:

  30 million yuan

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