Metronidazole tablets

1. This product is a nitroimidazole derivative that can inhibit the redox reaction of amoeba and break the nitrogen chain of the protozoa. 2. In vitro tests have shown that when the drug concentration is 1~2mg/L, the histolytica can undergo morphological changes in 6~20 hours and all are killed within 24 hours. The concentration of 0.2mg/L can kill the histolytica within 72 hours. 3. This product has a strong effect of killing trichomonas, and its mechanism is unknown. Metronidazole has a killing effect on anaerobic microorganisms. The metabolites generated when it is reduced in the human body also have anti-anaerobic effects, inhibiting the synthesis of bacterial deoxyribonucleic acid, thereby interfering with the growth and reproduction of bacteria, and ultimately causing bacterial death. It has a carcinogenic effect on some animals.

The main ingredient of this product is metronidazole

This product is white or off-white tablets.

It is used to treat intestinal and extraintestinal amebiasis (such as amoebic liver abscess, pleural amebiasis, etc.). It can also be used to treat vaginal trichomoniasis, balantidiasis, cutaneous leishmaniasis, guinea worm infection, etc. It is also widely used to treat anaerobic infections.

1. Common dosage for adults: ① Intestinal amebiasis, 0.4~0.6g once, 3 times a day, for 7 days; extraintestinal amebiasis, 0.6~0.8g once, 3 times a day, for 20 days. ② Giardiasis, 0.4g once, 3 times a day, for 5~10 days. ③ Guinea worm disease, 0.2g once, for 7 days. ④ Balantidiasis, 0.2g once, 2 times a day, for 5 days. ⑤ Cutaneous leishmaniasis, 0.2g once 2. Common dosage for children: ① Amebiasis, 35~50mg/kg per day, divided into 3 times for oral administration, for 10 days as a course of treatment. ② Giardiasis, 15~25mg/kg per day, divided into 3 times for oral administration, for 10 days as a course of treatment.

Adverse reactions occur in 15-30% of cases, with digestive tract reactions being the most common, including nausea, vomiting, loss of appetite, and abdominal cramps, which generally do not affect treatment; neurological symptoms include headache, dizziness, occasional paresthesia, limb numbness, ataxia, multiple neuritis, etc., and high doses can cause convulsions. A small number of cases develop urticaria, flushing, itching, cystitis, dysuria, metallic taste in the mouth, and leukopenia, all of which are reversible and recover on their own after stopping the drug.

Contraindicated in patients with active central nervous system disorders and blood diseases

Precautions for children: Refer to the content under Usage and Dosage for children. Precautions for pregnancy and lactation: Pregnant and lactating women are prohibited. Precautions for the elderly: This experiment has not been conducted and there is no reliable reference document.

This product can enhance the effect of anticoagulants such as warfarin. When used in combination with oxytetracycline, it can interfere with the effect of metronidazole in clearing vaginal Trichomonas.

Keep in dark place and sealed

0.2 g

24 months

HUAZHONG Pharmaceutical Co., Ltd.

• Founded in:

  2002-08-12

• Address:

  No. 118, Xianshan Road, Xiangyang City, Hubei Province

• Tax NO.:

  9142060017931210XL

• Registered Funds:

  245,148,515 yuan

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