Domperidone Tablets 10mg OTC

This product acts directly on the gastrointestinal wall, increasing gastrointestinal motility and tension, promoting gastric emptying, increasing gastric antrum and duodenal motility, coordinating pyloric contraction, and also enhancing esophageal motility and the tension of the lower esophageal sphincter, inhibiting nausea and vomiting. This product is not easy to pass through the blood-brain barrier.

Each tablet of this product contains the main ingredient domperidone 10 mg, and the auxiliary ingredients are: starch, hydrogenated cottonseed oil, lactose, magnesium stearate, microcrystalline cellulose, povidone K90, pregelatinized starch, and sodium lauryl sulfate.

This product is white tablets

Used for indigestion, bloating, belching, nausea, vomiting, and abdominal pain.

Oral administration: Adults take 1 tablet at a time, 3 times a day, 15-30 minutes before meals.

1. Occasionally mild abdominal cramps, dry mouth, rash, headache, diarrhea, nervousness, fatigue, drowsiness, dizziness, etc. 2. Sometimes it causes increased serum prolactin levels, galactorrhea, gynecomastia, etc., but they return to normal after stopping the drug. 3. Excitement and amenorrhea occur in rare cases. 4. Very rare adverse reactions include angioedema, allergic reactions, itching, abnormal liver function tests, convulsions, urticaria, extrapyramidal side effects (such as drooling, hand tremors, etc., these symptoms can be completely recovered after stopping the drug).

1. It is contraindicated for patients with pheochromocytoma, breast cancer, mechanical intestinal obstruction, gastrointestinal bleeding, etc.; 2. It is contraindicated for patients with known allergies to domperidone or any of the ingredients of this product; 3. It is contraindicated when increased gastric motility may be dangerous (for example: gastrointestinal bleeding, seasonal obstruction, perforation); 4. It is contraindicated for patients with pituitary tumors that secrete prolactin (prolactinoma); 5. It is contraindicated for use in combination with oral ketoconazole, erythromycin or other strong CYP3A4 enzyme inhibitors that may prolong the QTc interval (for example: fluconazole, voriconazole, clarithromycin, amiodarone, telithromycin).

Precautions for children: Due to the incomplete development of the blood-cerebrospinal fluid barrier in children under 1 year old, the possibility of central nervous system side effects in infants under 1 year old cannot be ruled out. Precautions for pregnancy and lactation: Use with caution in pregnant women. Precautions for the elderly:

1. It should not be used together with azole antifungal drugs such as ketoconazole and itraconazole, macrolide antibiotics such as erythromycin, HIV protease inhibitors and nefazodone. 2. Anticholinergic drugs such as tamoxifen, propantheline bromide, anisodamine, belladonna tablets, etc. will weaken the effect of this product and should not be taken with this product. 3. Antacids and drugs that inhibit gastric acid secretion can reduce the bioavailability of this product and should not be taken with this product. 4. If used with other drugs at the same time, drug interactions may occur. Please consult a doctor or pharmacist for details.

Keep in a light-proof and airtight container.

10 mg

24 months

Xian Janssen Pharmaceutical Ltd.

• Founded in:

  1985-10-22

• Address:

  No. 19, Caotang 4th Road, Caotang Science and Technology Industrial Base, High-tech Zone, Xi'an, Shaanxi Province, 17F, Huicheng International, No. 4, Gaoxin 5th Road, High-tech Zone, Xi'an, Shaanxi Province

• Tax NO.:

  91610000623100825C

• Registered Funds:

  284.317164 yuan

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