Tosufloxacin Tosylate Tablets

This product is a broad-spectrum quinolone antibacterial drug. It has antibacterial effects on the following bacteria in vitro: Gram-positive bacteria: Pneumococcus, Streptococcus pyogenes, Streptococcus pyogenes, Enterococcus, Staphylococcus, etc. Gram-negative bacteria: Enterobacteriaceae such as Acinetobacter, Proteus, Citrobacter, Salmonella (except Salmonella typhi and paratyphoid), Serratia and Escherichia coli, etc. Other Gram-negative bacteria include Pseudomonas aeruginosa, Neisseria gonorrhoeae, Haemophilus influenzae, etc. Anaerobic bacteria: Streptococcus peptostreptococcus, Propionibacterium acnes, etc. This product achieves antibacterial or bactericidal effects by inhibiting bacterial DNA gyrase.

The main component of this product is tosufloxacin tosylate, and its chemical name is 7-[3-amino-1-(pyrrolidinyl)]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid p-toluenesulfonate monohydrate. Its molecular formula: C19H15F3N4O3.C7H8O3S.H2O molecular weight: 594.57

This product is a film-coated tablet, which appears off-white after removing the film coating.

It is suitable for the following infections caused by sensitive bacteria: 1. Upper and lower respiratory tract infections: pharyngitis, tonsillitis, acute and chronic bronchitis, pneumonia. 2. Urogenital system infections: pyelonephritis, cystitis, prostatitis, epididymitis, urethritis, endometritis. 3. Biliary tract infections. 4. Intestinal infections: bacterial dysentery, enteritis. 5. Skin and soft tissue infections: folliculitis (including pustular acne), furuncle, carbuncle, erysipelas. 6. Eye, ear, nose, oral infections: blepharitis, tarsal gland inflammation, dacryocystitis, external otitis, otitis media, paranasal sinusitis, periodontitis. 7. Others: mastitis, trauma and surgical wound infection.

Oral administration: 0.3-0.45g per day for adults, divided into 2-3 doses. For patients with severe infection, 0.6g per day, divided into 2-3 doses.

1 Allergic reactions: fever, dyspnea, edema, interstitial pneumonia, photosensitivity, rash, itchy skin, eosinophilia. 2 Digestive system reactions: nausea, vomiting, poor appetite, diarrhea. 3 Headache, insomnia, fatigue, cramps, thrombocytopenia. 4 Occasionally, acute renal insufficiency, agranulocytosis, pseudomembranous colitis, hypoglycemia, and abnormal liver function may occur.

1. Patients who are allergic to this product or quinolone drugs are prohibited from using this product. 2. Pregnant women, lactating women and patients under 18 years old are prohibited from using this product.

Precautions for children: Fluoroquinolones can cause permanent damage to the cartilage of weight-bearing joints in dogs, leading to lameness, and can also cause arthritis in several other underage animals. They are contraindicated in patients under 18 years of age. In infections caused by multidrug-resistant bacteria, when the bacteria are only sensitive to fluoroquinolones, this product can only be used in children after weighing the pros and cons. Precautions for pregnancy and lactation: Fluoroquinolones can pass through the blood-placental barrier and can be secreted into breast milk. Their concentration is close to the blood drug concentration, so they are contraindicated for pregnant and lactating women. Precautions for the elderly: Elderly patients have reduced renal function, and the dosage should be reduced as appropriate.

1. It is not suitable to be taken at the same time with non-steroidal anti-inflammatory analgesics such as phenylacetic acid and fenbutyric acid. If the two are taken at the same time, it may cause cramps. 2. It is not suitable to be taken at the same time with antacids or iron preparations containing calcium and magnesium. If the two are taken at the same time, the absorption of this product will be reduced. 3. The aluminum and magnesium contained in didanosine (DDI) preparations can chelate with fluoroquinolones and should not be used together.

Keep away from light and store in sealed container.

75mg

24 months.

Zhuhai Tongyuan Pharmaceutical Co., Ltd.

• Founded in:

  1990-05-11

• Address:

  No. 6, Jinhai East Road, Sanzao, Jinwan District, Zhuhai City

• Tax NO.:

  91440400192522224J

• Registered Funds:

  50 million yuan

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