Granisetron Hydrochloride Injection
Function and Efficacy
It is a highly selective 5-HT3 receptor antagonist, which has a good preventive and therapeutic effect on nausea and vomiting caused by radiotherapy, chemotherapy and surgery. Factors such as radiotherapy, chemotherapy and surgery can cause enterochromaffin cells to release 5-HT, which can activate the 5-HT3 receptors of the central nervous system or vagus nerve and cause vomiting reflex. The mechanism of this product to control nausea and vomiting is to antagonize the 5-HT3 receptors in the central chemoreceptor area and peripheral vagus nerve endings, thereby inhibiting the occurrence of nausea and vomiting. This product has high selectivity and no adverse reactions such as extrapyramidal reactions and excessive sedation.
Ingredients
Granisetron hydrochloride.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Granisetron HydrochlorideIngredients |
It is a highly selective 5-HT3 receptor antagonist, which has a good preventive and therapeutic effect on nausea and vomiting caused by radiotherapy, chemotherapy and surgery. It inhibits the occurrence of nausea and vomiting by antagonizing the 5-HT3 receptors in the central chemoreceptor area and peripheral vagus nerve endings. This product has high selectivity and no adverse reactions such as extrapyramidal reactions and excessive sedation. More |
107007-99-8 | 35 |
Indication
This product is used to prevent or treat nausea and vomiting caused by chemotherapy, and to prevent and treat postoperative nausea and vomiting
Usage and Dosage
Intravenous injection: The adult dosage is usually 3 mg, diluted with 20-50 ml of 5% glucose injection or 0.9% sodium chloride injection, and injected intravenously 30 minutes before treatment. The administration time should exceed 5 minutes. Most patients only need to be given once, and the prevention effect on nausea and vomiting can exceed 24 hours. If necessary, the number of administrations can be increased by 1-2 times, but the maximum daily dose should not exceed 9 mg. Patients with liver and kidney dysfunction do not need to adjust the dosage.
Adverse Reactions
Common adverse reactions include headache, fatigue, fever, constipation, and occasional transient asymptomatic increase in liver aminotransferase. These reactions are mild and do not require special treatment.
Precautions
1. Patients who are allergic to this product or related compounds are prohibited from using this product. 2. Patients with gastrointestinal obstruction are prohibited from using this product.
Storage
Keep away from light and store in a sealed container below 30℃.
Packaging Specification
3ml:3mg (based on granisetron)
Manufacturer
HE BEI YI PIN Pharmaceutical Co., Ltd.
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Founded in:
2013-05-29 -
Address:
Sanxia Road, Shijiazhuang Economic and Technological Development Zone -
Tax NO.:
911300000694342458 -
Registered Funds:
68.68 million yuan -
Email: