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Vildagliptin Pharma Grade buy - large image1
Vildagliptin Pharma Grade buy - image1

Vildagliptin Pharma Grade

5 Inquiries

Unit Price: Get Latest Price
CAS No.:

274901-16-5

Grade:

Pharmaceutical Grade

Port:

QINGDAO

Packaging:

25kg/10kg Drum

Price valid (until):

2017-02-02

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Pharmacological action: Vigliptin is a selective, competitive and reversible DPP24 inhibitor. Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like polypeptide 21 (GLP21) are important hormones for maintaining glucose concentration in the body, and both have insulinotropic effects. The insulin-promoting effect of GIP in type 2 diabetic patients is impaired, and only GLP21 can exert the secretion-promoting effect of insulin-promoting hormone, which promotes the secretion of insulin by acting on receptors on the islet β-cell membrane. GLP21 can also inhibit glucagon secretion and gastric emptying to increase satiety (suppression of appetite). DPP24 binds to proteins in many tissues, such as the brush border of the kidney, liver, and small intestinal membranes, pancreatic ducts, lymphocytes, and endothelial cells, which can be quickly inactivated by hydrolyzing GLP21 N-terminal alanine at position 2 . This product inhibits the activity of this enzyme by combining with DPP24 to form a DPP24 complex. While increasing the concentration of GLP21 and promoting the production of insulin by islet β cells, it reduces the concentration of glucagon, thereby lowering blood glucose. And there is no obvious effect on body weight.

    Basic Info
    Product Name:

    Vildagliptin

    Other Name:

    2-Pyrrolidinecarbonitrile,1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-,(2S)-;2-Pyrrolidinecarbonitrile,1-[[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-,(2S)-;(2S)-1-[2-[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2-pyrrolidinecarbonitrile;Vildagliptin;LAF 237;NVP-LAF 237;Galvus;Equa;DSP 7238;(S)-1-[2-[(3-Hydroxyadamant-1-yl)amino]acetyl]pyrrolidine-2-carbonitrile;(2S)-1-[2-[(3-Hydroxy-1-adamantyl)amino]acetyl]pyrrolidine-2-carbonitrile;Xiliarx;Jalra;565453-38-5

    CAS No.:

    274901-16-5

    Molecular Formula:

    C17H25N3O2

    InChIKeys:

    InChIKey=SYOKIDBDQMKNDQ-XWTIBIIYSA-N

    Molecular Weight:

    303.39900

    Exact Mass:

    303.40

    ATC Code:

    A10BH02|A10BD08|A - Alimentary tract and metabolism

    HScode:

    2933990090

    Characteristics
    PSA:

    76.36000

    XLogP3:

    1.50308

    Appearance:

    white crystalline powder

    Density:

    1.27 g/cm3

    Melting Point:

    148-150 °C @ Solvent: Ethyl acetate, Isopropanol

    Boiling Point:

    531.3ºC at 760 mmHg

    Flash Point:

    275.1ºC

    Hazard Identification

    Classification of the substance or mixture

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 4

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    H413 May cause long lasting harmful effects to aquatic life

    Precautionary statement(s)
    Prevention

    P273 Avoid release to the environment.

    Response

    none

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Location:

    Tianyuan Development zones, Deyang, Sichuan

    SiChuan Tongsheng Biopharmaceutical CO., LTD established at 2011, located in development zone in Deyang with comfortable weather and pleasant view connected with high way directly to Chengdu,70 KM to Shuangliu airport.We mainly focus on the research of intermediates towards to Cardiovascular Drugs, anti-cancer drugs, Hepatitis C drug include Vildagliptin, linagliptin, Alogliptin, sitagliptin, sofosbuvir, Ledipasvir etc,The company has the complete set of R&D Center leading by 3 Doctors with 31 Lab stuff and equipments of different test scale.Our research group owns the best chemical, medicine filed background and abundant experience of management and technics. For now, a range of cooperations have been built with the unit like Chinese Academy of Science and so on, For sure, we will provide the comprehensive and efficient chemical customized service to our clients.The total area of the plant covers over 21000 m2 which includes the refining-drying-packing workshop about 2100 m2 and synthetise workshop about 2600 m2. The yearly production cabability can reach over 1000 MT and we are hanling the skills like nitrogen protection, reaction within -78~240℃, reaction within 5~12 Mpa maturely. We have followed the every GMP requirment to design and build the facility and producing line. It is our purpose to grow up to a contributive APIs enterprise within 3 year and realising the amount of sales over 100 millions.Along with the complete management system and quality control team,technics research group, satisfactory selling and after-sales service allowus to be confident to our procuction and expangding. We regard thehonesty and quality as the source of life, so we want to share the ideasof “symbiosis , common prosperity and win-win”with all of you whowould like to be a part in the future of medical chemistry.

  • Inquiry History
    5 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Vildagliptin

    5 MT Nov 25, 2025
    Russia

    vildagliptin

    2000 KG May 22, 2026
    India

    Vildagliptin

    100 KG Feb 13, 2026
    Tunisia

    Vildagliptin

    80 KG Dec 19, 2023
    India

    VILDAGLIPTIN

    100 KG Jul 22, 2025
    Post an enquiry for this product
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