Neostigmine Methyl Sulfate 99%
1 Inquiries
51-60-5
Chemical grade
99%
SHANGHAI
1kg/2.6kg Cardboard Drum
2019-05-08
chemicals,low price LCZ696 Intermediate,NICOTINAMIDE RIBOSIDE，NR,,4-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine,Romidepsin (FK228, Depsipeptide),Alpha-GPC
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceNeostigmine methyl sulfate is a reversible inhibitor of acetylcholinesterase, can not cross the blood-brain barrier.
Neostigmine methyl sulfate is an arylammonium sulfate salt. It has a role as an EC 3.1.1.8 (cholinesterase) inhibitor.|A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
Neostigmine is a reversible inhibitor of acetylcholinesterase (AChE; Kd= 260 μM). In a rat model of knee joint inflammation, intrathecal administration of neostigmine (2-30 μg) increases endogenous acetylcholine levels and dose-dependently increases the latency of paw withdrawal in response to thermal and mechanical stimuli (ED50s = 6.6 and 3.5 μg, respectively). Neostigmine (5 μg, i.p.) restores muscle action potentials in mice with a thymopoietin-induced neuromuscular block. Formulations containing neostigmine have been used in the treatment of myasthenia gravis and Ogilvie syndrome.
Crystalline Solid
ChEBI: Neostigmine methyl sulfate is an arylammonium sulfate salt. It has a role as an EC 3.1.1.8 (cholinesterase) inhibitor.Basic Info-
Product Name:
Neostigmine Methyl Sulfate
Other Name:A sulfuric acid neostigmine;(3-(dimethylcarbamoyloxy)phenyl)trimethyl-ammoniumethylsulfate;(3-hydroxyphenyl)trimethylammoniummethylsulfatedimethylcarbamicester;(m-hydroxyphenyl)trimethylammoniummethylsulfatedimethylcarbamate;PROSTIGMINE;NEOSTIGIMINE BROMIDE;NEOSTIGMINE METHYL SULFATE;NEOSTIGMINE METHYL SULPHATE
CAS No.:51-60-5
Molecular Formula:C12H19N2O2.CH3O4S
InChIKeys:OSZNNLWOYWAHSS-UHFFFAOYSA-M
Molecular Weight:334.39
Exact Mass:334.119843
EC Number:200-109-5
UNII:98IMH7M386
NSC Number:93753
DSSTox ID:DTXSID40199003
Color/Form:white
HScode:29242990
Categories:
Characteristics-
PSA:
104
XLogP3:2.11750
Appearance:white powder
Melting Point:175-177 °C(lit.)
Boiling Point:457ºC
Water Solubility:1g/10mL
Storage Conditions:−20°C
Toxicity:LD50 in mice (mg/kg): 0.16 i.v.; 0.42 s.c.; 7.5 orally, (Randall, Lehmann)
Flammability characteristics:Combustible, decomposes toxic nitrogen oxides, sulfur oxides gas when burning
Critical Temperature & Pressure:-20°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
Acute toxicity - Category 1, Dermal
Acute toxicity - Category 1, Inhalation
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
H310 Fatal in contact with skin
H330 Fatal if inhaled
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P262 Do not get in eyes, on skin, or on clothing.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P284 [In case of inadequate ventilation] wear respiratory protection.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P316 Get emergency medical help immediately.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P320 Specific treatment is urgent (see ... on this label).
Storage P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
chemicals,low price LCZ696 Intermediate,NICOTINAMIDE RIBOSIDE，NR,,4-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine,Romidepsin (FK228, Depsipeptide),Alpha-GPC
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Location:
No 7 ,Huacai International Building,Dengcai Road,Sandun,Westlake District,Hangzhou,Zhejiang
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Payment Terms:
L/C,100% TT in advance
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Average lead Time:
30
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
101-200
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Year of Establishment:
2011
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Certifications:
ISO,FDA,CE
Gihi Chemicals: is specialized in the production of ester products which are used in the daily dietary supplements chemicals ,cosmetic products and skincare products since 1999.
Since 2010，GIHI CHEMICALS , begun to focus on the development and production of high-quality healthy Dietary supplements for our global high-reputation customers. The purity of all healthy Dietary supplements we provide has reached more than 99% purity. From the beginning of our products’ development, our technical engineers have chosen and design the production routes to ensure that we have been able to use biological, enzyme and water-phase green synthesis methods during the large production process to ensure that our health dietary supplements is truly high-quality ,green &environmental friendly, which are truly good and health to the human body.
Now our company has:
1 sales & management center + 3 research centers+ 4 production factories.
with ISO9001 & FDA certificate & CE certificate, accordance with GMP requirements.
1 Sales &Management center:
Add:No.567 Dengcai Street, Sandun, Westlake District, Hangzhou 310030, Zhejiang, China.
Research Center 1: (Chemical synthesis lab)
No.6, Chanyexietongchuanxing Center, Kangyang Road, Shangyu Economic and Technological Development Zone, Shaoxing, Zhejiang，China.
This research center: is specialized in chemical synthesis, our this research center could synthesis more than 300 new chemical products for many china pharmaceutical companies every year.
Research Center 2:(For Enzyme biology technical and Enzyme catalyst technical)
No.7, Lixiangxi Road, changsha Economic and Technological Development Zone, Changsha, Hunan.
Our this research center is committed to the applications of immobilized enzymes technology to the development of products such as peptides, polysaccharides, and non-natural amino acids. The products developed are widely used in medicine, health products, cosmetics, food, feed and other industries. The company adopts multidisciplinary technologies of chemistry, materials science and life sciences, which helps to meet the demand of green production while improving product quality and economic benefits. And also helps to reduces the emission of "three industrial pollution" greatly.
Research Center 3:(Biology enzyme-catalytic products)
No.2 Bio-hatch Building,No.10 Gaoxinzhongyidao, Yuehai Street,Nanshan District, Shenzhen, Guangdong, China.
This research center is specialized in biosynthesis technology as the core technology, and multi-disciplinary cross-application as target. We are the first batch company in the world to apply enzyme catalysis technology to the large-scale production of peptides, carbohydrates and nucleic acids and other special functional raw materials, and actively explore products in new application in the field. In this center, we used enzyme catalyst production methods to produce many high lever products, such as: NMN, (S)-Prox-ylane, Ectoin, Ergothioneine,etc.
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
Pakistan
Neostigmine Methylsulfate
3 KG Aug 13, 2024 Post an enquiry for this product
