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L-Methionine | CAS 63-68-3 | Amino Acid for Food Fortification, Food and Health Ingredients

Name: L-Methionine | CAS 63-68-3 | Amino Acid for Food Fortification, Food and Health Ingredients
Brand: PREMIUM INGREDIENT
SKU: pr2106251211
Price: 4000 USD
Availability: InStock

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CAS No.:

63-68-3

Grade:

USP/AJI/FCC/EP grade

Content:

99%

Brand:

PREMIUM INGREDIENT

Packaging:

25kg/Cardboard Drum

Sample Available:

Yes

Price valid (until):

2026-06-17

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PREMIUM INGREDIENT CO.,LTD

Company Type:

Manufactory

Location:

United Kingdom

Payment Terms:

TT against copy of documents,L/C

Average Lead Time:

80 days

Qualification:

Main Products:

l-lysine monohydrochloride,dl-methionine,n-acetyl-l-cysteine,l-methionine,glycine,l-cysteine hcl monohydrate

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Product Description
Seller Information
Inquiry History

Description

Basic Information

L-Methionine
CAS Number	63-68-3
Molecular Formula	C₅H₁₁NO₂S
Molecular Weight	149.21
Appearance	White crystalline powder or colorless transparent crystal
Purity Specification	99% Food Grade (High Purity)
Executive Standard	USP / CP /EP/AJI/FCC
Certifications	ISO, HALAL, KOSHER
Solubility	Soluble in water, slightly soluble in ethanol

Product Overview

L-Methionine, Cas No.: 63-68-3, is an essential sulfur-containing amino acid that human bodies cannot synthesize and must obtain from external intake. As a key nutritional fortifier for food, it is widely used in functional foods and dietary supplements. It acts as a precursor of glutathione, supporting liver metabolism and antioxidant protection to maintain normal human physiological function. Additionally, this ingredient also has large consumption in animal feed to balance amino acid nutrition for livestock. It can also be applied as raw material for high-purity clinical nutritional preparations.

Character

L-Methionine is a stable essential amino acid with regular white crystalline morphology and pure texture, possessing excellent water solubility and good compatibility with various food raw materials. The product has stable physical and chemical properties under conventional storage and processing conditions, no peculiar smell, and will not produce harmful substances during food thermal processing. Adopting advanced enzymatic transformation production technology, it avoids chemical solvent residue risks, conforms to international food safety specifications. With high purity and low impurity content, it can be fully absorbed and utilized by the human body, showing outstanding safety and applicability in food fortification and nutritional supplement formulas.

Main Functions

Essential Amino Acid Supplementation: As one of the indispensable amino acids for human growth and metabolism, L-Methionine effectively supplements daily amino acid deficiency, balances human nutritional structure, and improves the absorption and utilization efficiency of dietary protein.

Support Liver Metabolism and Antioxidation: It is an important synthetic precursor of glutathione, a key antioxidant in the human body. It assists liver detoxification and metabolic operation, reduces oxidative damage to human cells, and maintains liver health and normal metabolic circulation.

Food Nutritional Enhancement: It can fortify the amino acid nutrition of grain products, special meals and functional foods, make up for the nutritional defects of conventional daily diets, and improve the overall nutritional value of food products.

Maintain Human Physiological Balance: Participate in human protein synthesis and amino acid metabolism regulation, support normal body growth, tissue repair and physiological operation, and assist in maintaining body health stability.

Applications

Dietary Supplement: It is a classic raw material for amino acid nutritional supplements, widely used in compound amino acid tablets, capsules and powder formulas, targeting daily nutritional supplementation, physical conditioning and antioxidant health care for human body.

Food Industry: Serves as a professional food nutritional fortifier, commonly added in flour, cereal products, baked foods and special formula foods to optimize amino acid proportion and enhance the nutritional value of finished food products.

Animal Feed: Widely used as feed additive to supplement essential amino acids, balance feed nutrition, and promote the healthy growth of livestock.

Pharmaceutical Nutrition: High-purity food-grade L-Methionine can be used as auxiliary raw material for special medical nutritional formulas and compound amino acid preparations, providing safe and stable amino acid supplement for human clinical nutrition regulation.

Packaging and Storage

Packaging: 25kg /drum

Storage: Store in a dry, cool, ventilated and clean warehouse environment, avoid direct sunlight, high temperature and humid environment. Keep sealed during storage to prevent moisture absorption and agglomeration. Strictly store separately from toxic and harmful substances. The shelf life is 2 years under original packaging and qualified storage conditions。

Test item	specifications
Assay	98.5% to 101.5%
Identification	Infrared absorption
Specific rotation	+22.4° to +24.7°
PH	5.6 to 6.1
Loss on drying	Not more than 0.3%
Residue on ignition	Not more than 0.4%
Sulfate	Not more than 0.03%
Iron	Not more than 0.003%
Heavy metals	Not more than 0.0015%
Chromatographic purity	Not more than 0.5% of any individual impurity is found, and not more than 2.0% of total impurities is found
Organic volatile impurities	Meets the requirements
Chloride	Not more than 0.05%

Product Name: L-Methionine

Cas No.63-68-3

Conforms to: AJI, USP, EP, FCC

Test item	specifications
Assay	98.5% to 101.5%
Identification	Infrared absorption
Specific rotation	+22.4° to +24.7°
PH	5.6 to 6.1
Loss on drying	Not more than 0.3%
Residue on ignition	Not more than 0.4%
Sulfate	Not more than 0.03%
Iron	Not more than 0.003%
Heavy metals	Not more than 0.0015%
Chromatographic purity	Not more than 0.5% of any individual impurity is found, and not more than 2.0% of total impurities is found
Organic volatile impurities	Meets the requirements
Chloride	Not more than 0.05%

ECHEMI Editorial Reference

L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
Minute hexagonal plates from dilute alcohol. (NTP, 1992)|Solid
Minute hexagonal plates from dilute alcohol. (NTP, 1992)|L-methionine is the L-enantiomer of methionine. It has a role as a nutraceutical, a micronutrient, an antidote to paracetamol poisoning, a human metabolite and a mouse metabolite. It is an aspartate family amino acid, a proteinogenic amino acid, a methionine and a L-alpha-amino acid. It is a conjugate base of a L-methioninium. It is a conjugate acid of a L-methioninate. It is an enantiomer of a D-methionine. It is a tautomer of a L-methionine zwitterion.|A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.|Methionine is one of nine essential amino acids in humans (provided by food), Methionine is required for growth and tissue repair. A sulphur-containing amino acid, methionine improves the tone and pliability of skin, hair, and strengthens nails. Involved in many detoxifying processes, sulphur provided by methionine protects cells from pollutants, slows cell aging, and is essential for absorption and bio-availability of selenium and zinc. Methionine chelates heavy metals, such as lead and mercury, aiding their excretion. It also acts as a lipotropic agent and prevents excess fat buildup in the liver. (NCI04)|A sulfur-containing essential L-amino acid that is important in many body functions.

Certificates

Basic Info

Product Name:

l-Methionine

Other Name:

L-Methionine;Methionine,L-;Cymethion;Methionine;Butanoic acid,2-amino-4-(methylthio)-,(S)-;2-Amino-4-(methylthio)butyric acid;S-Methionine;α-Amino-γ-methylmercaptobutyric acid;γ-Methylthio-α-aminobutyric acid;(S)-2-Amino-4-(methylthio)butanoic acid;l-Methionine;L-α-Amino-γ-methylthiobutyric acid;L-Homocysteine,S-methyl-;h-Met-oh;Acimethin;NSC 22946;S-Methyl-L-homocysteine;Secretory peptide (human clone HTXDU73);Methiorep;Meth-o-Tas;(2S)-2-Azaniumyl-4-methylsulfanylbutanoate;(2S)-2-Amino-4-(methylsulfanyl)butanoic acid;7005-18-7;24425-78-3;1437749-32-0;1437749-60-4;1437749-65-9;1437749-75-1;1437749-80-8;1437769-00-0;1437870-94-4;1437870-95-5;1437870-97-7;1437870-98-8;1437871-20-9;1463481-01-7;1463481-06-2;1463481-15-3;1463481-19-7;1463481-23-3;1463481-27-7;1463481-31-3;1463481-37-9;1463481-41-5;1463481-46-0;1463481-51-7;1463481-58-4;1463481-73-3;1463481-80-2;1463481-89-1;1463610-75-4;1463610-76-5;1466415-57-5

CAS No.:

63-68-3

Molecular Formula:

C5H11NO2S

InChIKeys:

InChIKey=FFEARJCKVFRZRR-BYPYZUCNSA-N

Molecular Weight:

149.21100

Exact Mass:

149.21

EC Number:

200-562-9

UNII:

AE28F7PNPL

NSC Number:

760117

DSSTox ID:

DTXSID5040548

NCI Thesaurus Code:

C29600

Color/Form:

Minute hexagonal plates from dilute alcohol|Colorless or white, lustrous plates or as white, crystalline powder

ATC Code:

V - Various

HScode:

2930400000

Categories:

Amino Acids and Derivatives

Characteristics

PSA:

88.62000

XLogP3:

-1.9

Appearance:

Minute hexagonal plates from dilute alcohol. (NTP, 1992)

Density:

1.206 g/cm3

Melting Point:

280-282 °C (decomp)

Boiling Point:

123-126 °C @ Press: 15 Torr

Flash Point:

139.4ºC

Refractive Index:

1.531

Water Solubility:

H2O: soluble

Storage Conditions:

Store at RT.

Vapor Pressure:

8.14X10-8 mm Hg at 25 deg C (est)

Toxicity:

LD50 oral in rat: 36gm/kg

Specific rotation:

Specific optical rotation: 22.5 deg at 25 °C/D (1 N HCl)

Odor:

Faint

Taste:

Sulfurous

PH:

pH (1% aqueous solution) = 5.6-6.1

PKA:

2.28(at 25 °C)

Henrys Law Constant:

Henry's Law constant = 2.11X10-11 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

2.28 (at 25 °C)|pKa = 2.28; pK2 = 9.21

Collision Cross Section:

133.65 Å² [M+H]+ [CCS Type: DT, Method: stepped-field]|152.05 Å² [M-H]- [CCS Type: DT, Method: stepped-field]|127 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine]|133.1 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|132 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|134.08 Å² [M+H]+ [CCS Type: DT, Method: stepped-field]|140.5 Å² [M-H]-

Experimental Properties:

Platelets from alcohol. mp 281 °C (decomposes), density 1.340; pKa1 = 2.28, pKa2 = 9.21; pH of 1% aqueous solution 5.6-6.1; Rf value 0.77. Solubility in water (g/L) at 0 °C: 18.18; at 25 °C: 33.81; at 50 °C: 60/.70; at 75 °C: 15.2 °C. Soluble in dilute acids, alkalies. Very slightly soluble in 95% alcohol. Insoluble in ether. /Methionine, DL-form/|UV: 1-65 (Organic Electronic Spectral Data, Phillips et al, John Wiley & Sons, New York) /Methionine (DL)/|Hydroxyl radical reaction rate constant = 5.13X10-11 cu cm/molec-sec at 25 °C (est)

Air and Water Reactions:

Reacts with water, steam, and/or acids to produce toxic and flammable vapors of hydrogen sulfide (NTP, 1992). Water soluble (NTP, 1992). pH of 1% aqueous solution is 5.6-6.0.

Reactive Group:

Sulfides, Organic

Reactivity Profile:

An organosulfide and amine derivative, carboxylic acid. Look at Reactive Groups 20 (organosulfides), 7 (amines), and 3 (carboxylic acids) may give indications about reactive tendencies. It is an amino acid essential in human nutrition.

See More l-Methionine Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Separated from strong oxidants. Well closed.

See More l-Methionine Safety Data Sheet 

Seller Information

Business Type: Manufactory
Main Products: l-lysine monohydrochloride,dl-methionine,n-acetyl-l-cysteine,l-methionine,glycine,l-cysteine hcl monohydrate
Location: dongsheng road
Payment Terms: TT against copy of documents,L/C
Average lead Time: 80 days
Total Annual Revenue: $5 million-$10 million
Total Employees: 5-10
Year of Establishment: 2015

Premium Ingredient specializes in supplying and distributing food & feed amino acids, food additives and functional ingredients for more than a decade.

Our food additives portfolio covers phosphates, acidulants, preservatives, sweeteners, thickeners and leavening agents.

Our functional ingredients include vitamins, mineral products, botanical extracts, nutraceutical ingredients, functional fibers & bulking agents.

We serve over 100 clients across food & beverage, dietary supplement, sports nutrition, personal care, pharmaceutical and animal feed sectors, with products exported to dozens of countries worldwide. All our goods are sourced from top-tier Chinese manufacturers with proven expertise and complete management systems.

◆Amino Acids	◆ phosphates	◆ acidulants
◆ preservatives	◆ sweeteners	◆ functional fiber&bulking agent
◆ thickeners	◆ Leavening agents	◆ mineral products
◆ Botanical extracts	◆ vitamins	◆ nutritional products

Backed by over 10 years of industry experience, we provide one-stop-shop solutions combining high-grade products, prompt communication, on-time delivery and real-time market intelligence. Thanks to our long-term deep-rooted partnerships with source manufacturers, we can guarantee sufficient inventory, stable pricing and fast shipment.

Our third-party certifications include ISO9001, ISO14001, HACCP, HALAL, KOSHER, GMP, FAMI-QS and more. You can count on Premium Ingredient as your trusted global raw material supplier.

------------------------------------- Mission------------------------------------

Acting as a bridge between reliable Chinese manufacturers and global buyers, we carefully select partner factories with mature production capabilities and sound management systems. We deliver not only premium-quality raw materials, but also value-added services including market trend updates, supply chain risk alerts, product formulation consultation, consolidated sample shipment and full document support for import compliance. We timely forward overseas customers’ requirements to our partner factories to support product upgrading and achieve mutual growth.

-------------------------------------Our Quality------------------------------------

Our Quality

As a professional ingredient supplier, we do not operate manufacturing facilities. Instead, we build robust quality‑assurance workflows across our whole supply chain to safeguard consistent product performance for every shipment

Strict Supplier Due‑Diligence

Before entering any partnership, we carry out on-site factory visits and assess industry reputation, followed by multi-stage qualification reviews. We validate production qualifications, export track records, quality management systems and complete certification packages. New suppliers must pass sample evaluation, and only fully vetted top-tier factories are admitted to our approved supplier pool

Batch‑by‑batch Document Verification

For every order, we cross‑check factory‑issued test documents against agreed specifications including FCC, USP, EP, AJI, CP or your customized requirements. We will not forward documents to customers until key indicators are fully aligned with specifications. This step avoids inconsistent or mismatched documentation common in raw‑material trade.

Independent Third‑party Testing Coordination

Upon client request, we can arrange independent laboratory inspections from recognized third‑party institutions. We manage sample delivery, test protocol communication and report follow‑up to support your market compliance needs.

Quality Closure & Continuous Improvement

We keep traceable records for all delivered batches. If any quality concern arises, we act as your single point‑of‑contact to trace root causes with source factories, drive corrective actions and deliver practical resolution plans. Client feedback is systematically collected to optimize our supplier management and document‑review procedures.

We provide a comprehensive set of compliance documents to support your import and registration work. Our available documentation includes but is not limited to:

★ ISO Certification ★ Halal Certificate

★ Kosher Certificate ★ IP certificate

★ Haccp certificate ★ Allergens with Glutens

★ GRAS Statement ★ HACCP Program

★ BSE/TSE Statement ★ Certificate of Analysis

★ Country of Origin Certificate ★ Material Safety Data Sheet

★ Flow Chart (product processing) ★ Food Grade Certificate

★ Nutritional Information ★ GMO Statement

★ Specification Sheet

Inquiry History

36 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	L-Methionine	100.00 KG	Jun 6, 2025
Malaysia	L-Methionine	20.00 MT	Apr 1, 2026
Malaysia	L-Methionine	20.00 MT	Jun 16, 2026
India	L-Methionine	1 KG	Apr 7, 2026
Greece	METHIONINE	300 KG	Sep 24, 2025
Belgium	DL-Methionine	4 40' Fcl	Sep 18, 2025
Algeria	methionine	1 KG	Jul 23, 2025
India	L-Methionine	5.00 MT	Jul 17, 2025
India	L-Methionine	1 MT	Apr 23, 2025
India	L-METHIONINE	25.00 KG	Mar 25, 2025
Vietnam	Methionine	140 MT	Aug 27, 2024
India	L-Methionine	1.00 KG	Aug 21, 2026
India	Methionine	1.00 20' Fcl	May 25, 2026
India	L-Methionine	1.00 20' Fcl	Apr 27, 2026
India	L-Methionine	200.00 KG	Nov 10, 2025
India	L-Methionine	5.00 MT	Jul 16, 2025
India	L-Methionine	10.00 TON	Jul 9, 2025
India	L-Methionine	7.00 KG	Jul 9, 2025
Bangladesh	L-methionine	1 MT	Feb 5, 2025
Singapore	L-Methionine	1 MT	Feb 7, 2024

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