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Sorafenib tosylate

1 Inquiries

Unit Price: Get Latest Price
CAS No.:

284461-73-0

Grade:

Pharmaceutical Grade

Content:

99%

Packaging:

As per Customer's requirement

Price valid (until):

2021-08-31

Company Type:
Distributor
Location:
China
Qualification:
Main Products:

API,Intermediate

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    ItemsSpecifications
    Melting point 202-204°C
    Boiling point 523.3±50.0 °C(Predicted)
    density 1.454±0.06 g/cm3(Predicted)
    storage temp. -20°C Freezer
    pka12.89±0.70(Predicted)
    form White to off-white solid.

    Basic Info
    Product Name:

    Sorafenib

    Other Name:

    2-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-;4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide;BAY 43-9006;Sorafenib;N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea;Nevaxar

    CAS No.:

    284461-73-0

    Molecular Formula:

    C21H16ClF3N4O3

    InChIKeys:

    InChIKey=MLDQJTXFUGDVEO-UHFFFAOYSA-N

    Molecular Weight:

    464.825

    Exact Mass:

    464.82

    EC Number:

    608-209-4

    UNII:

    9ZOQ3TZI87

    NSC Number:

    747971

    DSSTox ID:

    DTXSID7041128

    NCI Thesaurus Code:

    C61948

    Color/Form:

    White solid

    ATC Code:

    L01EX02|L01XE05|L - Antineoplastic and immunomodulating agents

    HScode:

    29350090

    Categories:

    Antineoplastic Agents

    Characteristics
    PSA:

    92.35000

    XLogP3:

    4.1

    Appearance:

    White to off-white solid

    Density:

    1.5±0.1 g/cm3

    Melting Point:

    215 °C

    Boiling Point:

    523.3±50.0 °C at 760 mmHg

    Flash Point:

    270.3±30.1 °C

    Refractive Index:

    1.626

    Water Solubility:

    1.71e-03 g/L

    Storage Conditions:

    Store at 25 deg C (77 deg F); excursions permitted to 15-30 deg C (59-86 deg F)

    Vapor Pressure:

    4.76E-11mmHg at 25°C

    Vapor Density:

    4.11X10-14 mm Hg at 25 deg C (est)

    Henrys Law Constant:

    Henry's Law constant = 1.85X10-20 atm-cu m/mol at 25 °C (est)

    Experimental Properties:

    White to yellowish or brownish solid. Practically insoluble in aqueous media, slightly soluble in ethanol and soluble in PEG 400 /Sorafenib tosylate/

    Hazard Identification

    Classification of the substance or mixture

    Reproductive toxicity, Category 1B

    Reproductive toxicity, Additional category for effects on or via lactation

    Specific target organ toxicity – repeated exposure, Category 1

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H360 May damage fertility or the unborn child

    H362 May cause harm to breast-fed children

    H372 Causes damage to organs through prolonged or repeated exposure

    H410 Very toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P263 Avoid contact during pregnancy and while nursing.

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P273 Avoid release to the environment.

    Response

    P318 IF exposed or concerned, get medical advice.

    P319 Get medical help if you feel unwell.

    P391 Collect spillage.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Distributor

    Main Products:

    API,Intermediate

    Payment Terms:

    TT against copy of documents,L/C

    Average lead Time:

    30

    Total Annual Revenue:

    Above $100 million

    Total Employees:

    201-300

    About Echemi Pharmaceutical 

    Echemi’s philosophy is to seek for higher quality, to explore frontier area. The progress of human society, the extension of life expectancy, and the conquest of disease are all derived from the numerous businesses and individuals who have quietly dedicated themselves in the pharmaceutical industry. It’s the controlling of supply chain quality that ensures the efficacy. It’s the continuous exploration that promotes the development of the pharmaceutical industry and benefits more future generations. The pursuit of high quality requires all partners of Echemi Pharmaceutical to be screened, whether its certificate, qualification or scale. In the field of renewal, we will embrace all new changes and make more contributions to the development of pharmaceutical industry.

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    Advantage for Pharmaceutical 

    • Having been working in pharmaceutical field for more then 15 years, we have experienced regulatory team, quality control team, sourcing team, technical support team, and logistics team. And we are familiar with the regulatory requirements from different areas, can offer tailored service for our customers.

    • We have hundreds of strategic partners for APIs, intermediates, and custom synthesis. All of our partners are ready to support our customers with documents, and be audited.

    • We can offer custom synthesis for some new chemical structures and some materials which there are no reliable suppliers.

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    Product Category 

    We care for human and animal health and we are committed to creating a better social environment.

    •  Human API

    • Intermediate

    • Veterinary API

    • Agrochemical

    • Fine Chemical

    • Custom Synthesis



  • Inquiry History
    1 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Sorafenib

    10 G Nov 14, 2023
    Post an enquiry for this product
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