Vildagliptin 99.0% White to off-white crystalline powder Yuanjinchem
5 Inquiries
274901-16-5
Pharmaceutical Grade
99%
Shanghai
Yuanjinchem
25kg/drum
2022-06-24
Pharmaceutical intermedaite,Agricultural chemical intermediate
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Product Details
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceVildagliptin (LAF-237; NVP-LAF 237) inhibits DPP-4 with IC50 of 2.3 nM.IC50 Value: 2.3 nM[1]Target: DPP-4in vitro: Vildagliptin is an N-substituted glycyl-2-cyanopyrrolidine (figure 2). It is a potent competitive and reversible inhibitor of human and rodent DPP-4 in vitro, with a median inhibitory concentration (IC50) ~2-3 nmol/L. Importantly, vildagliptin inhibits DPP-4 with high specificity relative to other similar peptidases where its IC50 exceeds 200 mol/L [1].in vivo: Compared to a
A pyrrolidine-carbonitrile derivative and potent inhibitor of DIPEPTIDYL PEPTIDASE 4 that is used in the treatment of TYPE 2 DIABETES MELLITUS.Basic Info-
Product Name:
Vildagliptin
Other Name:2-Pyrrolidinecarbonitrile,1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-,(2S)-;2-Pyrrolidinecarbonitrile,1-[[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-,(2S)-;(2S)-1-[2-[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2-pyrrolidinecarbonitrile;Vildagliptin;LAF 237;NVP-LAF 237;Galvus;Equa;DSP 7238;(S)-1-[2-[(3-Hydroxyadamant-1-yl)amino]acetyl]pyrrolidine-2-carbonitrile;(2S)-1-[2-[(3-Hydroxy-1-adamantyl)amino]acetyl]pyrrolidine-2-carbonitrile;Xiliarx;Jalra;565453-38-5
CAS No.:274901-16-5
Molecular Formula:C17H25N3O2
InChIKeys:InChIKey=SYOKIDBDQMKNDQ-XWTIBIIYSA-N
Molecular Weight:303.39900
Exact Mass:303.40
ATC Code:A10BH02|A10BD08|A - Alimentary tract and metabolism
HScode:2933990090
Categories:
Characteristics-
PSA:
76.36000
XLogP3:1.50308
Appearance:white crystalline powder
Density:1.27 g/cm3
Melting Point:148-150 °C @ Solvent: Ethyl acetate, Isopropanol
Boiling Point:531.3ºC at 760 mmHg
Flash Point:275.1ºC
Hazard IdentificationClassification of the substance or mixture
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 4
GHS label elements, including precautionary statements
Pictogram(s) No symbol. Signal word No signal word
Hazard statement(s) H413 May cause long lasting harmful effects to aquatic life
Precautionary statement(s) Prevention P273 Avoid release to the environment.
Response none
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Pharmaceutical intermedaite,Agricultural chemical intermediate
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Location:
Jingxin building, No. 111 Lijiang Road, Xinchang County, Zhejiang Province
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A
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Average lead Time:
300 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2014
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Inquiry History5 Inquiries
Country Product Purchase Quantity Date Posted
Bangladesh
Vildagliptin
1000.00 KG Jul 1, 2026
India
Vildagliptin
100 KG Feb 13, 2026
India
Vildagliptin
5 MT Nov 25, 2025
India
VILDAGLIPTIN
100 KG Jul 22, 2025
Tunisia
Vildagliptin
80 KG Dec 19, 2023 Post an enquiry for this product
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