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Taltirelin TA-0910 99% powder 103300-74-9 Senwayer

Name: Taltirelin TA-0910 99% powder 103300-74-9 Senwayer
Brand: Senwayer
SKU: pr2203111249
Price: 280 USD
Availability: InStock

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CAS No.:

103300-74-9

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

Senwayer

Packaging:

1g/ vial

Sample Available:

Yes

Price valid (until):

2022-05-11

Contact Supplier

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Dingwang Technology (Wuhan) Co., Ltd.

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,L/C

Average Lead Time:

10 days

Qualification:

Main Products:

API,nutrition supplements,plant extract,peptide,HCG,6-Aminocaproic acid

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Product Details
Seller Information
Inquiry History

Description

Product Detail

Taltirelin (TA-0910), a synthetic thyrotropin-releasing hormone (TRH) analog, has been developed by Tanabe Seiyaku for the treatment of neurodegenerative diseases. An NDA was filed in Japan in April 1999 for the treatment of spinocerebellar degeneration (SCD) and was approved in July 2000; the drug was launched in Japan in September 2000. It is the first orally administered drug for this indication. In September 2001, UBS Warburg (Japan) stated that total sales of taltirelin in 2000 were Yen 3.5 bn, and estimated that sales in 2001 would reach Yen 7.6 bn, rising to Yen 8.6 bn by 2005. Also in this month, Morgan Stanley predicted that there would be sales of Yen 8 bn in 2001, rising to Yen 10 bn in 2002.

Product name	Taltirelin
CAS No.	103300-74-9
MF	C17H23N7O5
MW	405.41
Melting point	72-75°
Density	1.447±0.06 g/cm3(Predicted)
Storage condition	Store at +4°C

Side Effect
The adverse reactions of this product are mainly digestive system reactions, including vomiting, nausea and stomach discomfort. All adverse reactions were mild to moderate and disappeared during treatment and / or after withdrawal.

Attention
Use with caution in patients with impaired renal function.

About us

Wuhan senwayer century chemical Co.,Ltd located in the predominant WuHan City where is a traffic hinge of China,specilize in producing and developing pharmaceutical & its intermediates, Pesticide Intermediate, food additive, Plant extracts,and in distributing the products of our own company and affiliated enterprises.

We have set up R&D center, quality inspection center and manufacturing site in Wuhan, Jiangsu and others places.
Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. Meanwhile, we possess of complete Q.A. and Q.C. system, supply chemical products with good quality and custom-tailored products according to our clients' requirement.
We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc.

With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

Contact us

Wuhan Senwayer Century Chemical Co.,Ltd
TEL:86-27-59707018
Whatsapp:86-13627115097
Wechat:13627115097
Wickr:angie523
http://www.senwayer.com/
https://senwayer.en.made-in-china.com/
http://www.peptidepowders.com/

ECHEMI Editorial Reference

Taltirelin was marketed in Japan for the treatment of neurodegenerative diseases, in particular the improvement of ataxia due to spino-cerebellar degeneration (SCD); it is the first orally-active drug in this indication. This synthetic thyrotropin-releasing hormone (TRH) analog is prepared by condensation of (S)-1-methyl-4,5-dihydroorotic acid with L-histidyl-Lprolinamide. It was shown that the S-configuration for all 3 chiral centers is crucial for CNS activity. Taltirelin is a potent agon
Taltirelin is an oligopeptide comprising of (4S)-1-methyl-2,6-dioxohexahydropyrimidine-4-carboxylic acid, L-histidine and L-prolinamide joined in sequence by peptide linkages. It is a thyrotropin-releasing hormone (TRH) analog. Its tetrahydrate form is approved in Japan for the treatment of spinal muscular atrophy. It has a role as a nootropic agent, a neuroprotective agent and an analgesic.

Basic Info

Product Name:

Taltirelin

Other Name:

L-Prolinamide,(4S)-hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-L-histidyl-;L-Prolinamide,N-[(hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl)carbonyl]-L-histidyl-,(S)-;(4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-L-histidyl-L-prolinamide;TA 0910;Taltirelin;Ceredist

CAS No.:

103300-74-9

Molecular Formula:

C17H23N7O5

InChIKeys:

InChIKey=LQZAIAZUDWIVPM-SRVKXCTJSA-N

Molecular Weight:

405.41

Exact Mass:

405.41

UNII:

DOZ62MV6A5

DSSTox ID:

DTXSID0043763

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

171

XLogP3:

-4.09

Density:

1.447±0.06 g/cm3(Predicted)

Melting Point:

72-75 °C

Refractive Index:

1.612

Storage Conditions:

Store at +4°C

Specific rotation:

25D -13.6° (c = 1 in water)

See More Taltirelin Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Taltirelin Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
API,nutrition supplements,plant extract,peptide,HCG,6-Aminocaproic acid

Location:
Room 707, Block A, Zhongxing Times Digital Trade Port, No. 79 Xudong Street, Hongshan District, Wuhan City

Payment Terms:
TT against copy of documents,L/C

Average lead Time:
10 days

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
51-100

Year of Establishment:
2020

Company Certificates
- Verified supplier certificate
- SGS
Dingwang Technology (Wuhan) Co., Ltd located in the predominant WuHan City where is a traffic hinge of China,specilize in producing and developing pharmaceutical & its intermediates, Peptide, Nutritional supplements,food additive, Plant extracts,and in distributing the products of our own company and affiliated enterprises.
We have set up R&D center, quality inspection center and manufacturing site in Wuhan, Jiangsu and others places.
Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. Meanwhile, we possess of complete Q.A. and Q.C. system, supply chemical products with good quality and custom-tailored products according to our clients' requirement.
We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc.
With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
United Kingdom	Taltirelin	1 G	Dec 29, 2023

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Taltirelin TA-0910 99% powder 103300-74-9 Senwayer

Product Details

Seller Information