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LITHOCHOLIC ACID

Name: LITHOCHOLIC ACID
Brand: KieRay Chem
SKU: pr22040614145
Price: 100 USD
Availability: InStock

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CAS No.:

434-13-9

Grade:

industrial Grade

Content:

98%

Port:

SHANGHAI

Brand:

KieRay Chem

Packaging:

25kg/drum

Sample Available:

Yes

Price valid (until):

2022-12-31

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Hangzhou KieRay Chem Co.,LTD

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents,L/C

Average Lead Time:

15 days

Qualification:

Main Products:

fine chemicals,pharmaceutical materials

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Product Details
Seller Information

Description

Product Detail

Please enter the product introduction information...

Items	Specifications
Appearance	White or of- white powder or crystlline power,odorless
Solubility	Very soluble in N,N-Dimethylformamide,Soluble in methanol,Sparingly soluble inglacial acetic acid, Very slightly soluble inchloroform, Practically insoluble in water.
Melting Point	152°C~156°C

About US

Hangzhou KieRay Chem Co.,Ltd.is located in YuhangDistrict of Hangzhou City and specialized in the chemical product customization,development, sales, import and export. Current business is focused on finechemicals, pharmaceutical materials and intermediates, pesticides, dyes andbiochemical reagents.

Since establishment, we believe in"integrity-based, quality-oriented" to provide customers withexcellent products and quality services. Cooperating with universities, we havea high-level scientific research team; equipped with a professional andresponsible service sales team ; and established stable and reliable long-termcooperative relations with hundreds of domestic chemical factories. Throughunremitting efforts, our products have exported to North America, Europe,Southeast Asia, etc., and have established long-term business relationship withcustomers all over the world.

Our company is willing to work withour customers to create a better future!

Contact Us

Hangzhou KieRay Chem Co.,Ltd.

Tel: +86-15336573147

Whatspp: +86-15336573147

Telegram: : +86-15336573147

E-Mail: sales@kieraychem.com

Address: Room 260, Building 3, No. 76 Xingqiao North Road, Xingqiao Street, Yuhang District, Hangzhou City, Zhejiang Province, China

FAQ

1. Do you accept sample order?
We accept sample orders. We will make samples before bulk production, and after sample approved, we'll start to bulk production.

2. How to confirm the quality before placing the order
You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.

3. What’s the MOQ?

Our MOQ is 50g-1000g. But usually we accept less quantity such as 50g on the condition that sample charge is 100% paid.

4. Do you provide COA?
Yes. We'll provide certificate of analysis before shipment

ECHEMI Editorial Reference

Lithocholic acid is a toxic secondary bile acid, causes intrahepatic cholestasis, has tumor-promoting activity.Target: OthersLithocholic acid has been used in a study to assess cholestasis and its action on several organs and tissues in rats. It has also been used in a study to investigate the regulation of hepatic phospholipid and bile acid homeostasis through SMAD3 activation by TGFβ. It has been implicated in human and experimental animal carcinogenesis. Preliminary in vitro research
Hexagonal leaflets (from alcohols) or prisms (from acetic acid) or white powder. (NTP, 1992)|Solid
Hexagonal leaflets (from alcohols) or prisms (from acetic acid) or white powder. (NTP, 1992)|Lithocholic acid is a monohydroxy-5beta-cholanic acid with a alpha-hydroxy substituent at position 3. It is a bile acid obtained from chenodeoxycholic acid by bacterial action. It has a role as a human metabolite, a mouse metabolite and a geroprotector. It is a bile acid, a monohydroxy-5beta-cholanic acid and a C24-steroid. It is a conjugate acid of a lithocholate.|A bile acid formed from chenodeoxycholate by bacterial action, usually conjugated with glycine or taurine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as cholagogue and choleretic.

Basic Info

Product Name:

Lithocholic acid

Other Name:

Cholan-24-oic acid,3-hydroxy-,(3α,5β)-;5β-Cholan-24-oic acid,3α-hydroxy-;5β-Cholanic acid,3α-hydroxy-;(3α,5β)-3-Hydroxycholan-24-oic acid;3α-Hydroxycholanic acid;3α-Hydroxy-5β-cholanic acid;Lithocholic acid;3α-Hydroxy-5β-cholanoic acid;3α-Hydroxy-5β-cholan-24-oate;3-Hydroxycholan-24-oic acid;17β-(1-Methyl-3-carboxypropyl)etiocholan-3α-ol;3α-Hydroxy-5β-cholan-24-oic acid;NSC 683770;2360921-71-5

CAS No.:

434-13-9

Molecular Formula:

C24H40O3

InChIKeys:

InChIKey=SMEROWZSTRWXGI-HVATVPOCSA-N

Molecular Weight:

376.57

Exact Mass:

376.57

EC Number:

207-099-1

UNII:

5QU0I8393U

NSC Number:

683770

DSSTox ID:

DTXSID6020779

Color/Form:

HEXAGONAL LEAFLETS FROM ALC, PRISMS FROM ACETIC ACID

HScode:

29181998

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

57.5

XLogP3:

6.70

Appearance:

White to off-white Powder

Density:

1.1±0.1 g/cm3

Melting Point:

184-186 °C

Boiling Point:

511.0±23.0 °C at 760 mmHg

Flash Point:

9℃

Refractive Index:

35.5 ° (C=1, EtOH)

Water Solubility:

18.83ug/L(25 ºC)

Storage Conditions:

Refrigerator

Specific rotation:

D20 +33.7° (c = 1.5 in abs ethanol); D19 +23.3° (Wieland); D20 +32.1° (Fischer)

Collision Cross Section:

193.4 Å² [M+H-H2O]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|199.95 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|200.33 Å² [M-H]- [CCS Type: DT, Method: stepped-field]|203.1 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|210.8 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|198.9 Å² [M-H]- [CCS Type: DT, Method: single field calibrated]|191.6 Å² [M+H-H2O]+ [CCS Type: DT, Method: single field calibrated]|198.8 Å² [M+HCOO]- [CCS Type: DT, Method: single field calibrated]|204.1 Å² [M+K-H+HCOO]- [CCS Type: DT, Method: single field calibrated]|217.6 Å² [M+K-H+HCOO]- [CCS Type: DT, Method: single field calibrated]|197.9 Å² [M+Na-H+Cl]- [CCS Type: DT, Method: single field calibrated]|201.6 Å² [M+Na-H+HCOO]- [CCS Type: DT, Method: single field calibrated]|214.8 Å² [M+Na]+ [CCS Type: DT, Method: single field calibrated]|201.4 Å² [M-H]-

Experimental Properties:

CRYSTALS /ETHYL ESTER/|CRYSTALS /BENZYL ESTER/|CRYSTALS /ACETYLLITHOCHOLIC ACID/|FLAT NEEDLES FROM PENTANE /ACETYLLITHOCHOLIC ACID METHYL ESTER/|For more Other Experimental Properties (Complete) data for LITHOCHOLIC ACID (6 total), please visit the HSDB record page.

Air and Water Reactions:

Insoluble in water.

Reactive Group:

Acids, Carboxylic

See More Lithocholic acid Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Lithocholic acid Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
fine chemicals,pharmaceutical materials

Location:
Room 260, Building 3, No. 76 Xingqiao North Road, Xingqiao Street, Yuhang District, Hangzhou City, Zhejiang Province, China

Payment Terms:
TT against copy of documents,L/C

Average lead Time:
15 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2020

Company Profile
Hangzhou KieRay Chem Co.,Ltd.is located in YuhangDistrict of Hangzhou City and specialized in the chemical product customization,development, sales, import and export. Current business is focused on finechemicals, pharmaceutical materials and intermediates, pesticides, dyes andbiochemical reagents.
Since establishment, we believe in"integrity-based, quality-oriented" to provide customers withexcellent products and quality services. Cooperating with universities, we havea high-level scientific research team; equipped with a professional andresponsible service sales team ; and established stable and reliable long-termcooperative relations with hundreds of domestic chemical factories. Throughunremitting efforts, our products have exported to North America, Europe,Southeast Asia, etc., and have established long-term business relationship withcustomers all over the world.
Our company is willing to work withour customers to create a better future!
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LITHOCHOLIC ACID

Product Details

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