Top Quality Dasatinib Monohydrate CAS 863127-77-9
HALAL ISO FDA 1 Inquiries
863127-77-9
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Foil Bag
2022-12-31
Herb Extracts,Cosmetic raw materails,API
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Product Description
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Seller Information
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Inquiry History
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Description
Product Name: Dasatinib Monohydrate
Form: Powder
Purity: 99%
MF: C22H28ClN7O3S
CAS No.: 863127-77-9
Brand: Salus
COA: Available
Sample: Available
Shelf Life: 2 Years
Dasatinib is an oral Bcr-Abl tyrosine kinase inhibitor (inhibits the "Philadelphia chromosome") and Src family tyrosine kinase inhibitor approved for first line use in patients with chronic myelogenous leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). It is being evaluated for use in numerous other cancers, including advanced prostate cance
Specification:
Item
Specification
Appearance
White Powder
Assay(HPLC)
≥99%
Solutility
Insoluble in water and slightly soluble in ethanol and methanol
Identification
a)1H-NMR
b)Retention time(HPLC)
Conforms to standard
Conforms to standard
Melting point
275.0-286.0°C
Water Content(KF)
2.8-4.2%
Residue on ignition
≤0.2%
Heavy metals
≤20ppm
Related substances
Any single impurities
Total impurities
≤0.5%
≤1.0%
Dasatinib is an oral Bcr-Abl tyrosine kinase inhibitor (inhibits the "Philadelphia chromosome") and Src family tyrosine kinase inhibitor approved for first line use in patients with chronic myelogenous leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). It is being evaluated for use in numerous other cancers, including advanced prostate cancer.
CertificatesBasic Info-
Product Name:
Dasatinib monohydrate
Other Name:5-Thiazolecarboxamide,N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-,hydrate (1:1);5-Thiazolecarboxamide,N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-,monohydrate;BMS 35482503;Dasatinib hydrate;Dasatinib monohydrate
CAS No.:863127-77-9
Molecular Formula:C22H26ClN7O2S.H2O
InChIKeys:InChIKey=XHXFZZNHDVTMLI-UHFFFAOYSA-N
Molecular Weight:506.02082
Exact Mass:505.166
UNII:RBZ1571X5H
DSSTox ID:DTXSID50235486
NCI Thesaurus Code:C38713
HScode:29339900
Categories:
Characteristics-
PSA:
136
XLogP3:3.39810
Density:1.408 g/cm3
Melting Point:97-99 °C(lit.)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 2, Oral
Reproductive toxicity, Category 1B
Specific target organ toxicity â repeated exposure, Category 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H300 Fatal if swallowed
H360 May damage fertility or the unborn child
H361 Suspected of damaging fertility or the unborn child
H372 Causes damage to organs through prolonged or repeated exposure
H410 Very toxic to aquatic life with long lasting effects
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P318 IF exposed or concerned, get medical advice.
P319 Get medical help if you feel unwell.
P391 Collect spillage.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Herb Extracts,Cosmetic raw materails,API
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Location:
1403,Jinye B Block
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Payment Terms:
TT against copy of documents
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Average lead Time:
8
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2015
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
Japan
Dasatinib Monohydrate
100 G May 13, 2024 Post an enquiry for this product