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Anti-Diabetic Drug Gliclazide 99% CAS: 21187-98-4 Gliclazide

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CAS No.:

21187-98-4

Grade:

Pharmaceutical Grade

Content:

99%

Packaging:

Boil Bag

Price valid (until):

2022-12-31

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Xian ZB Biotech Co.,Ltd

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Herb Extracts,Cosmetic raw materails,API

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Product Description
Seller Information
Inquiry History

Description

Anti-diabetic drug Gliclazide 99% CAS: 21187-98-4 Gliclazide

iclazide	CAS 21187-98-4	Brand: TGY
	MW: 323.41	MSDS: Avaiable
	MF: C15H21N3O3S	Sample: Avaiable
	Category: Diabetes drug	Min order: 10grams
	Quality standard : EP7.0/BP2009	Place of Origin:China
Introduction	The treatment of type (II) diabetes
Character	A white or almost white powder
Applications	Pharmaceutical raw materials

Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug.It was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide. It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex. This FKBP12-FK506 complex interacts with and inhibits calcineurin thus inhibiting both T-lymphocyte signal transduction and IL-2 transcription.

Items	Acceptable criteria	Results
Characteristics	A white or almost white powder	A white powder
Solubility	Practically insoluble in water: freely soluble in methylene chloride; Sparingly soluble in acetone(96%); slightly soluble in alcohol (96%)	Conforms
M.P	162-166°C	164.0-164.5°C
Identification	Conform to the spectrum of the CRS Gliclazide	Conforms
Heavy metals	≤10ppm	<10ppm
Impurity B	≤2ppm	0.3ppm
Related substances	Impurity F ≤0.10%	<0.10%
	Other single impurity ≤0.10%	<0.10%
	Total of other impurities ≤0.2%	0.13%
Loss on drying	≤0.25%	0.1%
Sulphated ash	≤0.1%	0.01%
Residual solvents	Ethyl acetate ≤0.5%	Below LOQ
Residual solvents	Toluene ≤0.089%	Below LOQ
Assay (on dried basis)	99.0%-101.0%	99.5%
Conclusion	The test results conform with EP7.0/BP2009

Gliclazide is used for control of hyperglycemia in gliclazide-responsive diabetes mellitus of stable, mild, non-ketosis prone, type 2 diabetes. It is used when diabetes cannot be controlled by proper dietary management and exercise or when insulin therapy is not appropriate.

1. For adults with type 2 diabetes, diabetes associated with obesity or vascular lesions.
2. Hypoglycemic agents. It can be used for the treatment of non-insulin dependent diabetes mellitus.
3. Hypoglycemic agents, non-insulin dependent diabetes mellitus.

Certificates

Basic Info

Product Name:

Gliclazide

Other Name:

Benzenesulfonamide,N-[[(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methyl-;Urea,1-(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)-;Cyclopenta[c]pyrrole,benzenesulfonamide deriv.;N-[[(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methylbenzenesulfonamide;Gliclazide;Diamicron;S 1702;1-(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea;SE 1702;S 852;N-(4-Methylbenzenesulfonyl)-N′-[3-azabicyclo(3,3,0)oct-3-yl]urea;Diabezidum;Glinormax;Diabrezide;Diaprel;Glyzide;Glimicron;Diabyl;1-(3,3a,4,5,6,6a-Hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4-methylphenyl)sulfonylurea;1-(4-Methylbenzenesulfonyl)-3-[octahydrocyclopenta[c]pyrrol-2-yl]urea

CAS No.:

21187-98-4

Molecular Formula:

C15H21N3O3S

InChIKeys:

InChIKey=BOVGTQGAOIONJV-UHFFFAOYSA-N

Molecular Weight:

323.41

Exact Mass:

323.41

EC Number:

244-260-5

NSC Number:

758673

DSSTox ID:

DTXSID9023095

ATC Code:

A10BB09|A - Alimentary tract and metabolism

HScode:

29350090

Categories:

Hormones and the Endocrine System

Characteristics

PSA:

86.9

XLogP3:

2.6

Appearance:

white powder

Density:

1.2205 (rough estimate)

Melting Point:

181 °C

Refractive Index:

1.623

Water Solubility:

methylene chloride: soluble

Storage Conditions:

-20°C Freezer

Toxicity:

LD50 orally in mice: >3 g/kg (Duhault)

Collision Cross Section:

178 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

See More Gliclazide Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Gliclazide Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Herb Extracts,Cosmetic raw materails,API

Location:
1403,Jinye B Block

Payment Terms:
TT against copy of documents

Average lead Time:
8

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
11-50

Year of Establishment:
2015

Xian ZB Biotech Co.,Ltd is a leading Manufactory supplier of Arbutin, Nicotinamide, Flucytosine based in Xi'an, Shaanxi, China. With a commitment to quality and customer satisfaction, Xian ZB Biotech Co.,Ltd has become a trusted name in the industry. Our product line includes a range of high-quality Arbutin, Nicotinamide, Flucytosine, which are available at competitive prices. Xian ZB Biotech Co.,Ltd has established itself as a reliable supplier of chemical products on the echemi.com.

Inquiry History

7 Inquiries

Country	Product	Purchase Quantity	Date Posted
Bangladesh	Gliclazide BP	1800 KG	Nov 27, 2023
Bangladesh	Gliclazide BP	1800 KG	Nov 27, 2023
Sri Lanka	Gliclazide BP 2024 / BP 2025	18000 KG	Jun 19, 2026
Indonesia	Gliclazide	1 KG	Jun 9, 2025
Bangladesh	Gliclazide BP	1600 KG	Nov 28, 2023
Bangladesh	Gliclazide	4.00 MT	Dec 11, 2025
Bangladesh	Gliclazide BP	4 MT	Oct 24, 2025

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