Antiasthmatic Drugs Pranlukast Powder CAS 103177-37-3 Pranlukast
GMP HALAL KOSHER ISO FDA 1 Inquiries
103177-37-3
Pharmaceutical Grade
99%
Boil Bag
2022-12-31
Herb Extracts,Cosmetic raw materails,API
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Product Description
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Seller Information
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Inquiry History
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Description
Pranlukast Basic information Product Name: Pranlukast Synonyms: PRANLUKAST;4-oxo-8-(4-(4-phenylbutoxy)benzoylamino)-2-(tetrazol-5-yl)-4h-1-benzopyranh;benzamide,n-(4-oxo-2-(1h-tetrazol-5-yl)-4h-1-benzopyran-8-yl)-4-(4-phenylbutox;emihydrate;ONO-RS-411;ONO-RS-411-01;N-[4-keto-2-(2H-tetrazol-5-yl)chromen-7-yl]-4-(4-phenylbutoxy)benzamide;N-[4-oxo-2-(2H-1,2,3,4-tetrazol-5-yl)chromen-7-yl]-4-(4-phenylbutoxy)benzamide CAS: 103177-37-3 MF: C27H23N5O4 MW: 481.5 EINECS: 808-178-9 Product Categories: Aromatics;Heterocycles;Antiasthmatic;Inhibitors;Intermediates & Fine Chemicals;API;Pharmaceuticals Pranlukast Chemical Properties Melting point 236-238°C storage temp. Store at +4°C Merck 147710 CAS DataBase Reference 103177-37-3(CAS DataBase Reference) Pranlukast Spec.:
Test Specification
Appearance White powder
Melting point:231~235 °C
Biggest impurities: 0.2% max
Purity:99.0% min
Pranlukast is a common respiratory drug, it belongs to asthma drugs , it is the cysteinyl leukotrienes (LTs) receptor antagonist and it can bind to LTC4, LTD4, LTE4 receptors selectively to antagonize their effect . Roles and application are similar to zafirlukast. It is clinically used for the prevention of bronchial asthma. Oral 225mg once, 2 times one day, morning and evening after meal. After taking ,there may be gastrointestinal reactions,or there may be nausea, vomiting, abdominal pain, diarrhea or constipation, sometimes , fever, rash, pruritus and liver function abnormalities such as serum aminotransferase or bilirubin increase are visible . Pregnant women should use with caution , the elderly should take appropriate reductions. This product can not alleviate the onset of asthma.
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1, zafirlukast: it is effective for mild to moderate asthma ,it can cause improvement in dose-dependent lung function, and reduce the amount of β agonists. Absorption of the product is affected by food, it should not be taken together with food. Oral each 20mg, 2 times/d.
2, montelukast: it is valid for intermittent or persistent asthma in adults and children. This product is approved by the FDA for the treatment of children aged 6 to 12. Absorption of the product is not affected by food, it can be taken with food . Oral each 10mg, once/d.
3, pranlukast: it is used for mild to moderate asthma, pranlukast can increase patients maximum expiratory flow,and improve asthma symptoms, it can be used as a daily treatment of chronic asthma. Each oral 450mg, 2 times/d.
CertificatesBasic Info-
Product Name:
Pranlukast
Other Name:Benzamide,N-[4-oxo-2-(2H-tetrazol-5-yl)-4H-1-benzopyran-8-yl]-4-(4-phenylbutoxy)-;Benzamide,N-[4-oxo-2-(1H-tetrazol-5-yl)-4H-1-benzopyran-8-yl]-4-(4-phenylbutoxy)-;N-[4-Oxo-2-(2H-tetrazol-5-yl)-4H-1-benzopyran-8-yl]-4-(4-phenylbutoxy)benzamide;RS 411;ONO 1078;Pranlukast;ONO-RS 411;SB 205312;8-[4-(4-Phenylbutoxy)benzoyl]amino-2-(5-tetrazolyl)-4-oxo-4H-1-benzopyran;Onon;CCN 00401;Azlaire;4-Oxo-8-[4-(4-phenylbutoxy)benzoylamino]-2-(tetrazol-5-yl)-4H-1-benzopyran
CAS No.:103177-37-3
Molecular Formula:C27H23N5O4
InChIKeys:InChIKey=NBQKINXMPLXUET-UHFFFAOYSA-N
Molecular Weight:481.5
Exact Mass:481.50
EC Number:201-616-4
UNII:TB8Z891092
DSSTox ID:DTXSID9021180|DTXSID3043782
ATC Code:R - Respiratory system
Categories:
Characteristics-
PSA:
119
XLogP3:4.2
Appearance:off-white solid
Density:1.374±0.06 g/cm3(Predicted)
Melting Point:236-238°C
Refractive Index:1.681
Storage Conditions:Store at +4°C
Toxicity:LD50 in male mice (mg/kg): >1000 i.v. (Toda)
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Herb Extracts,Cosmetic raw materails,API
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Location:
1403,Jinye B Block
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Payment Terms:
TT against copy of documents
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Average lead Time:
8
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2015
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
Switzerland
Antiasthmatic Drugs Pranlukast Powder CAS 103177-37-3 Pranlukast
10000 MT Aug 28, 2023 Post an enquiry for this product