Supply Anti-Hypertension Drugs Losartan Potassium 124750-99-8
HALAL ISO FDA 9 Inquiries
124750-99-8
0%
ZB
Foil Bag, Box, Drum
2022-12-31
Herb Extracts,Cosmetic raw materails,API
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Product Description
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Seller Information
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Inquiry History
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Description
Product Name Losartan potassium CAS NO 124750-99-8 Molecular Formula C22H23ClKN6O Molecular Weight 462.01 Appearance powder Losartan potassium------------COA
Items of analysis Specification Results Characters White or off white crystalline powder off white powder Solubility Free soluble in water and methanol, very slightly soluble in chloroform Conforms Infraed absorption Must similar to reference standard Conforms Ultraviolet absorption Must similar to reference standard Conforms Test for potassium Must be positive positive Water ≤0.5% 0.20% Heavy metals ≤10ppm <10ppm Single impurity ≤0.2% 0.07% Total impurity ≤0.5% 0.12% Isopropyl alcohol ≤2000ppm 234ppm Assay 98.5-101% 99.8% Conclusion Qualified 
ECHEMI Editorial ReferenceWhite to Off-White Crystalline PowderAs a angiotensin II receptor antagonist, Losartan Potassium is the potassium salt of losartan with antihypertensive activity, which is mainly used in the therapy of high blood pressure (hypertension) and diabetic nephropathy. It functions by relaxing blood vessels so that blood can flow more easily. It is also effective to help protect the kidneys from damage caused by diabetes and lower the risks of stroke in patients suffering from hypertension
Losartan is an angiotensin II receptor blocker used in the therapy of hypertension and diabetic nephropathy. Losartan is associated with a low rate of transient serum aminotransferase elevations and has been linked to rare instances of acute liver injury.|Losartan Potassium is the potassium salt of losartan, a non-peptide angiotensin II receptor antagonist with antihypertensive activity. Losartan selectively and competitively binds to the angiotensin II receptor (type AT1) and blocks the binding of angiotensin II to the receptor, thus promoting vasodilatation and counteracting the effects of aldosterone. Converted from angiotensin I by angiotensin-converting enzyme (ACE), angiotensin II stimulates the adrenal cortex to synthesize and secrete aldosterone, decreasing sodium excretion and increasing potassium excretion, and acts as a vasoconstrictor in vascular smooth muscle.|An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.CertificatesBasic Info-
Product Name:
Losartan potassium
Other Name:1H-Imidazole-5-methanol,2-butyl-4-chloro-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-,potassium salt (1:1);1H-Imidazole-5-methanol,2-butyl-4-chloro-1-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-,monopotassium salt;DuP 753;Du Pont 753;MK 954;Losartan potassium;Cozaar;Nu-Lotan;Losartan monopotassium salt;Zaart;Losacar;Losium;Aradois;Losartan potassium salt;Losar;Presartan 50;Losata;Tancin;Amosar;Losatan potassium;Potassium 5-(4′-((2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl)methyl)-[1,1′-biphenyl]-2-yl)tetrazol-1-ide;405554-24-7;1017795-20-8;1202865-13-1;1262770-26-2
CAS No.:124750-99-8
Molecular Formula:C22H23ClN6O.K
InChIKeys:InChIKey=FDKIDFYIEWFERB-UHFFFAOYSA-N
Molecular Weight:462.01
Exact Mass:460.118068
EC Number:200-287-4
UNII:3ST302B24A
DSSTox ID:DTXSID3044209
NCI Thesaurus Code:C29165
ATC Code:B - Blood and blood forming organs
HScode:2933290000
Categories:
Characteristics-
PSA:
77.7
XLogP3:3.89590
Appearance:white to off-white crystalline powder
Density:0.986 g/mL at 25 °C(lit.)
Melting Point:183.5-184.5 °C
Boiling Point:682°C at 760 mmHg
Flash Point:366.3ºC
Refractive Index:n20/D 1.387(lit.)
Water Solubility:Freely soluble in water and in methanol, slightly soluble in acetonitrile.
Storage Conditions:Desiccate at RT
Vapor Pressure:1.55E-19mmHg at 25°C
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Herb Extracts,Cosmetic raw materails,API
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Location:
1403,Jinye B Block
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Payment Terms:
TT against copy of documents
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Average lead Time:
8 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2015
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Inquiry History9 Inquiries
Country Product Purchase Quantity Date Posted 
India
Losartan Potassium
5 MT Sep 4, 2025
India
Losartan Potassium
10 MT Aug 29, 2025 
Pakistan
LOSARTAN POTASSIUM
50 KG Mar 18, 2024 
Sri Lanka
Losartan Potassium BP 2024 / BP 2025
6000 KG Jun 19, 2026
India
Losartan potassium
1 MT Jun 27, 2024 
Bangladesh
Losartan Potassium BP
1800.00 KG Nov 11, 2023 
Bulgaria
losartan potassium
50 G May 20, 2026
Bangladesh
Losartan potassium
1500.00 KG Dec 11, 2025
India
Losartan Potassium
2.00 MT Mar 31, 2025 Post an enquiry for this product
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