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PERPHENAZINE

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CAS No.:

58-39-9

Content:

99%

Packaging:

Bottle,barrel,cargo,container,etc.

Sample Available:

Yes

Price valid (until):

2026-11-25

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HANGZHOU LEAP CHEM CO., LTD.

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C

Average Lead Time:

5 days

Qualification:

Main Products:

Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals

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Product Details
Seller Information
Inquiry History

Description

Keywords

58-39-9

PERPHENAZINE

C21H26ClN3OS

Quick Details

ProName:

PERPHENAZINE

CasNo:

58-39-9

Molecular Formula:

C21H26ClN3OS

Appearance:

powder, or liquid

Application:

Pharmaceuticals, intermediates, APIs, custom synthesis, chemicals

DeliveryTime:

5-7 Days

PackAge:

Bottle, barrel, cargo, container, etc.

Port:

Shanghai

Purity:

Storage:

Stored in room temperature, ventilated place

Transportation:

By air, ship, express, etc.

LimitNum:

Grade:

Industrial Grade

Superiority

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick Response

Details

LEAPChem supplies high quality Pharmaceuticals, intermediates, APIs, custom synthesis, fine chemicals and other industrial chemicals

ECHEMI Editorial Reference

Perphenazine is a typical antipsychotic drug, inhibits 5-HT2Areceptor, Alpha-1A adrenergic receptor, Dopamine receptor D2/D3, D2L receptor, and Histamine H1 receptor, with Ki values of 5.6, 10, 0.765/0.13, 3.4, and 8 nM, respectively.
Solid
Perphenazine is a phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10. It has a role as a phenothiazine antipsychotic drug, a dopaminergic antagonist and an antiemetic. It is a member of phenothiazines, a N-alkylpiperazine, a N-(2-hydroxyethyl)piperazine and an organochlorine compound. It derives from a hydride of a 10H-phenothiazine.|An antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine.|Perphenazine is a Phenothiazine.|Perphenazine is a phenothiazine and antipsychotic agent, now rarely used in clinical practice. Perphenazine can cause mild and transient serum enzyme elevations and is a rare cause of clinically apparent acute and chronic cholestatic liver injury.|Perphenazine is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties. Perphenazine blocks postsynaptic dopamine 2(D2) receptors in the mesolimbic and medullary chemoreceptor trigger zone (CTZ), thereby preventing the excess of dopamine in the brain. This leads to reduction in psychotic symptoms, such as hallucinations and delusions. Perphenazine appears to exert its antiemetic activity by blocking the dopamine and histamine-1 receptor in the CTZ thereby relieving nausea and vomiting in the brain. In addition, perphenazine binds to alpha-adrenergic receptors.|An antipsychotic phenothiazine derivative with actions and uses similar to those of CHLORPROMAZINE.

Basic Info

Product Name:

Perphenazine

Other Name:

1-Piperazineethanol,4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-;1-Piperazineethanol,4-[3-(2-chlorophenothiazin-10-yl)propyl]-;4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol;2-Chloro-10-3-[1-(2-hydroxyethyl)-4-piperazinyl] propyl phenothiazine;2-Chloro-10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazine;Decentan;Etaperazin;Etaperazine;Ethaperazine;Fentazin;1-(2-Hydroxyethyl)-4-[3-(2-chloro-10-phenothiazinyl)propyl]piperazine;γ-[4-(β-Hydroxyethyl)piperazin-1-yl]propyl-2-chlorophenothiazine;Perphenazin;Perphenazine;Trifaron;Trilafon;Trilifan;Chlorperphenazine;Perfenazine;Fentazine duolets;Fentazin syrup;Thilatazin;Tranquisan;Emesinal;Perphenan;PZC;Sch 3940;Triphenot;Chloriprozine;NSC 150866;Perfenil;Mutabom;PZC (tranquilizer);2-[4-[3-(2-Chloro-phenothiazin-10-yl)-propyl]-piperazin-1-yl]-ethanol;2-[4-[3-(2-Chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethanol;2-[4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl]ethan-1-ol;8055-48-9

CAS No.:

58-39-9

Molecular Formula:

C21H26ClN3OS

InChIKeys:

InChIKey=RGCVKNLCSQQDEP-UHFFFAOYSA-N

Molecular Weight:

403.97

Exact Mass:

403.97

EC Number:

200-381-5

UNII:

FTA7XXY4EZ

NSC Number:

758649|150866

DSSTox ID:

DTXSID1023441

NCI Thesaurus Code:

C29355

Color/Form:

Crystals|White to creamy-white powder

ATC Code:

N - Nervous system

HScode:

2934999090

Categories:

Nervous System Drugs

Characteristics

PSA:

55.2

XLogP3:

4.2

Appearance:

Solid

Density:

1.253

Melting Point:

94-100 °C

Boiling Point:

214-218 °C @ Press: 0.15 Torr

Flash Point:

304.8±30.1 °C

Refractive Index:

1.627

Water Solubility:

28.28mg/L(24 ºC)

Storage Conditions:

2-8°C

Vapor Pressure:

7.52X10-12 mm Hg at 25 deg C (est)

Toxicity:

Oral-Rat LD50: 318 mg/kg; Oral-Mouse LD50: 120 mg/kg

Flammability characteristics:

Combustible, decomposes toxic chloride, sulfur oxide and nitrogen oxide gas when burning

Odor:

Almost odorless

Taste:

Bitter taste

PH:

pH = 4.2 - 5.6

PKA:

7.94None

Henrys Law Constant:

Henry's law constant = 5.19X10-18 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

7.94|pKa = 7.94

Collision Cross Section:

193.2 Å² [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]|192 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Experimental Properties:

Osmolality of 5 mg/mL is 263 mOsm/kg|Sensitive to light

See More Perphenazine Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin sensitization, Category 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H317 May cause an allergic skin reaction
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P333+P317 If skin irritation or rash occurs: Get medical help. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store in tight, light-resistant container as defined in the USP-NF. This material should be handled and stored per label instructions to ensure product integrity.

See More Perphenazine Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals

Location:
Room A, 23rd Floor, No. 609 Yan'an Road, Gongshu District, Hangzhou, Zhejiang

Payment Terms:
TT against copy of documents,D/P,L/C

Average lead Time:
5 days

Total Annual Revenue:
Above $100 million

Year of Establishment:
2020

Company Certificates
- ISO
Company Profile
LEAPChem is a specialized fine chemical supplier for research, development and production.
LEAPChem provides nearly 200,000 rare and innovative chemical products to support the evolving needs of our customers in research & bulk manufacturing activities.
As a highly customer-oriented enterprise, we are committed to providing high-quality customer services and products to our global customers in a cost-effective and efficient manner.
Our client list includes many major pharmaceutical and science companies, universities, research institutions and chemical catalogue companies.

Methodology: Sound & Stable; Active & Innovative.
Attitude: Conscientious; Ingenious.
Goals: Customer's Satisfaction

We regard client's success as our success.
At LEAPChem, we strive to be the preferred supplier for efficiency increasing and cost lowering in your Research & Production.
To achieve this strategic vision, we always push ourselves to exceed our customer's requirement. By focusing on the aim of 'Beyond Your Expectation', we continually expand our product lines, and enhance our systematic management and human resources.
Welcome to contact us and we look forward to becoming your reliable and preferred partner.
LEAPChem is a specialized fine chemical supplier for research, development and production.
LEAPChem provides nearly 200,000 rare and innovative chemical products to support the evolving needs of our customers in research & bulk manufacturing activities.
As a highly customer-oriented enterprise, we are committed to providing high-quality customer services and products to our global customers in a cost-effective and efficient manner.
Our client list includes many major pharmaceutical and science companies, universities, research institutions and chemical catalogue companies.

Methodology: Sound & Stable; Active & Innovative.
Attitude: Conscientious; Ingenious.
Goals: Customer's Satisfaction

We regard client's success as our success.
At LEAPChem, we strive to be the preferred supplier for efficiency increasing and cost lowering in your Research & Production.
To achieve this strategic vision, we always push ourselves to exceed our customer's requirement. By focusing on the aim of 'Beyond Your Expectation', we continually expand our product lines, and enhance our systematic management and human resources.
Welcome to contact us and we look forward to becoming your reliable and preferred partner.
">Company Profile

Inquiry History

3 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Perphenazine	10 KG	Jul 23, 2025
India	Perphenazine	50 KG	May 23, 2026
India	Perphenazine USP	50 KG	May 21, 2026

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Product Name	Grade / Content	Price	Supplier Name	Details
High Quality 99% Perphenazine CAS 58-39-9 Powder Fast Shipping Best Price	Pharmaceutical Grade/99.5		Hangzhou Hyper Chemicals Limited	Inquiry
PERPHENAZINE.	/		Hefei Heyu Chemical New Materials Co., Ltd	Inquiry

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PERPHENAZINE

Product Details

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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