Calcium folinate
5 Inquiries
1492-18-8
99%
Bottle,barrel,cargo,container,etc.
2026-09-23
Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals
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Product Description
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Seller Information
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Inquiry History
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DescriptionKeywords
Calcium folinate
1492-18-8
C20H21N7O7.Ca
Quick DetailsProName:Calcium folinate
CasNo:1492-18-8
Molecular Formula:C20H21N7O7.Ca
Appearance:powder, or liquid
Application:Pharmaceuticals, intermediates, APIs, custom synthesis, chemicals
DeliveryTime:5-7 Days
PackAge:Bottle, barrel, cargo, container, etc.
Port:Shanghai
Purity:99
Storage:Stored in room temperature, ventilated place
Transportation:By air, ship, express, etc.
LimitNum:0
Grade:Industrial Grade
SuperiorityBest Seller, High Quality, Competitive Price, Fast Delivery, Quick Response
DetailsLEAPChem supplies high quality Pharmaceuticals, intermediates, APIs, custom synthesis, fine chemicals and other industrial chemicalsECHEMI Editorial ReferenceLeucovorin Calcium is a reduced folic acid.IC50 Value: 30 μM for zcSHMT and70 μM for zmSHMT [2]Target: Antifolatein vitro: Increasing concentrations of leucovorin (N5-CHO-THF) inhibit both zcSHMT and hcSHMT activities substantially, yet to a lesser extent than zmSHMT. The IC50 of leucovorin is approximately 30 μM for zcSHMT and higher than 70 μM for zmSHMT. The differential inhibition is evident with the presence of 10 μM leucovorin, the concentration estimated in serum in a high-dose le
Calcium folinate is a tetrahydrofolic acid.|The active metabolite of FOLIC ACID. Leucovorin is used principally as an antidote to FOLIC ACID ANTAGONISTS.Basic Info-
Product Name:
Calcium folinate
Other Name:L-Glutamic acid,N-[4-[[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-,calcium salt (1:1);Glutamic acid,N-[p-[[(2-amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-,calcium salt (1:1),L-;Calcium L-folinate;Calcium leucovorin;Calcium folinate;Calcium 5-formyltetrahydrofolate;Lederfoline;Leucovorin calcium;Leucovorin calcium salt;Folinic acid calcium salt;Rescuvolin;NSC 3590;Wellcovorin;Folidan;Folinate-SF calcium;6035-86-5;6209-45-6;30771-29-0;1236362-90-5
CAS No.:1492-18-8
Molecular Formula:C20H23N7O7.Ca
InChIKeys:InChIKey=BZPWXVJDMRBCMD-ZEDZUCNESA-N
Molecular Weight:511.5
Exact Mass:511.112823
EC Number:216-082-8
DSSTox ID:DTXSID3036999|DTXSID3045564|DTXSID20872448
ATC Code:V - Various
HScode:2942000000
Categories:
Characteristics-
PSA:
221
Appearance:powder
Melting Point:240-250ºC
Water Solubility:DMSO « 1 (mg/mL)
Specific rotation:(c = 1, H2O) [a]20 D = 13.0 ± 2º
Collision Cross Section:198.8 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|202.35 Ų [M-H]- [CCS Type: DT, Method: stepped-field]
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Skin sensitization, Category 1
Eye irritation, Category 2
Respiratory sensitization, Category 1
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H315 Causes skin irritation
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P284 [In case of inadequate ventilation] wear respiratory protection.
P271 Use only outdoors or in a well-ventilated area.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P333+P317 If skin irritation or rash occurs: Get medical help.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P342+P316 If experiencing respiratory symptoms: Get emergency medical help immediately.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals
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Location:
Room A, 23rd Floor, No. 609 Yan'an Road, Gongshu District, Hangzhou, Zhejiang
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Payment Terms:
TT against copy of documents,D/P,L/C
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Average lead Time:
5
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Total Annual Revenue:
Above $100 million
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Year of Establishment:
2020
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Certifications:
ISO
">Company ProfileLEAPChem is a specialized fine chemical supplier for research, development and production.
LEAPChem provides nearly 200,000 rare and innovative chemical products to support the evolving needs of our customers in research & bulk manufacturing activities.
As a highly customer-oriented enterprise, we are committed to providing high-quality customer services and products to our global customers in a cost-effective and efficient manner.
Our client list includes many major pharmaceutical and science companies, universities, research institutions and chemical catalogue companies.
Methodology: Sound & Stable; Active & Innovative.
Attitude: Conscientious; Ingenious.
Goals: Customer's Satisfaction
We regard client's success as our success.
At LEAPChem, we strive to be the preferred supplier for efficiency increasing and cost lowering in your Research & Production.
To achieve this strategic vision, we always push ourselves to exceed our customer's requirement. By focusing on the aim of 'Beyond Your Expectation', we continually expand our product lines, and enhance our systematic management and human resources.
Welcome to contact us and we look forward to becoming your reliable and preferred partner.
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Inquiry History5 Inquiries
Country Product Purchase Quantity Date Posted 
Netherlands
Calcium Folinate (Folinic Acid)
1 G Apr 10, 2025 
India
Calcium Folinate
1 KG Jul 9, 2025 
Pakistan
Leucovorin Calcium
500 G Dec 30, 2024 
Australia
Calcium folinate
10 G Jun 12, 2026 
United States
Folinic acid
1 KG Apr 21, 2025 Post an enquiry for this product
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