2-Deoxy-D-glucose 99% white powder Professional Producer Greenbo
2 Inquiries
154-17-6
Pharmaceutical Grade
99%
Shanghai
Greenbo
25kg Drum
2022-07-31
Active Pharm Ingredients,Chemical Catalyst,Pharmaceutical Intermediates,Flavors and Fragrances,Agrochemicals,Chemical Pesticides
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial Referencewhite to light yellow crystal powde
2-deoxyglucose is predominantly used as a diagnostic agent in its radiolabelled form (fluorine-18 is used as the radiolabel). By using positron emission tomography (PET), radiolabelled 2-deoxyglucose can determine glucose metabolism, which is altered in diseases such as cardiovascular disease, tumors, and Alzheimer's disease. Therapeutically, 2-deoxyglucose is an investigational drug that is being studied as an anticancer and antiviral agent. Concerning the former, 2- deoxyglucose was used as an adjunct to chemotherapy and radiotherapy in the treatment of solid tumors (lung, breast, pancreas, head, neck, and gastric tumors). The exact mechanisms of action of 2-deoxyglucose is still being investigated, but it is known that in hypoxic cancer cells, 2-deoxyglucose is a glycolysis inhibitor that prevents ATP production and, ultimately, cell survival. With respect to antiviral therapy, 2-deoxyglucose was shown to be effective against herpes simplex virus by affecting the virus' ability to penetrate cells. As an experimental drug, 2-deoxyglucose was demonstrated to work as an anticonvulsant in temporal lobe epilepsy. In this condition, 2-deoxyglucose represses the expression of certain proteins that are at high levels after a seizure. Although there are several possible therapeutic indications for 2-deoxyglucose, presently there is no approved indication for 2-deoxyglucose as a therapeutic agent.|2-Deoxy-D-glucose is a non-metabolizable glucose analog in which the hydroxyl group at position 2 of glucose is replaced by hydrogen, with potential glycolysis inhibiting and antineoplastic activities. Although the exact mechanism of action has yet to be fully elucidated, upon administration of 2-deoxy-D-glucose (2-DG), this agent competes with glucose for uptake by proliferating cells, such as tumor cells. 2-DG inhibits the first step of glycolysis and therefore prevents cellular energy production, which may result in decreased tumor cell proliferation.|2-Deoxy-D-arabino-hexose. An antimetabolite of glucose with antiviral activity.Basic Info-
Product Name:
2-Deoxyglucose
Other Name:D-arabino-Hexose,2-deoxy-;2-Deoxy-D-arabino-hexose;D-Glucose,2-deoxy-;2-Deoxyglucose;Ba 2758;2-Deoxy-D-glucose;2-Desoxy-D-glucose;2-Deoxy-D-mannose;NSC 15193;2 DG;2092-72-0;3724-71-8;4825-30-3;7640-18-8
CAS No.:154-17-6
Molecular Formula:C6H12O5
InChIKeys:InChIKey=VRYALKFFQXWPIH-PBXRRBTRSA-N
Molecular Weight:164.16
Exact Mass:164.16
BRN:1723331
EC Number:205-823-0
UNII:9G2MP84A8W
DSSTox ID:DTXSID1037648
NCI Thesaurus Code:C116618
HScode:29400090
Categories:
Characteristics-
PSA:
98
Appearance:white crystalline
Density:1.1738 (rough estimate)
Melting Point:146.5 °C
Boiling Point:211.61°C (rough estimate)
Flash Point:244.1±25.2 °C
Refractive Index:46.5 ° (C=1, H2O)
Water Solubility:soluble in water.H2O: 50 mg/mL, clear, colorless to faintly yellow
Storage Conditions:0-6°C
Specific rotation:45.5 º (c=2, H2O)
Hazard IdentificationClassification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
Pictogram(s) No symbol. Signal word No signal word
Hazard statement(s) none
Precautionary statement(s) Prevention none
Response none
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Active Pharm Ingredients,Chemical Catalyst,Pharmaceutical Intermediates,Flavors and Fragrances,Agrochemicals,Chemical Pesticides
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Location:
Zone K,Zwei Tianyuan Dushi Est,New Industial Park,High-tech Zone, Xian City,Shaanxi
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Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
15 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2017
Company Certificates-
international trade license
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FSSC2000
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted
Germany
2-deoxy-d-glucose
700 G May 26, 2026
United States
2-Deoxy-D-glucose
1 KG Feb 13, 2025 Post an enquiry for this product
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