Native Bovine Carbonic Anhydrase
4 Inquiries
9001-03-0
Yes
2026-11-23
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Details
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Seller Information
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Inquiry History
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Description
ProductName Native Bovine Carbonic Anhydrase Cat No NATE-0101 Description The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs relatively slowly in the absence of a catalyst. The active site of most carbonic anhydrases contains a zinc ion; they are therefore classified as metalloenzymes. Abbr Carbonic Anhydrase, Native (Bovine) Source Bovine Erythrocytes Species Bovine Applications CO2 determination in blood; Elimination of CO2 in reagents for acidity testing; Carboxy group transfers; Reduction reactions. Product Overview It was from Bovine Erythrocytes. A dialyzed, lyophilized powder. Form lyophilized powder Enzyme Commission Number EC 4.2.1.1 Activity > 3,000 units per mg dry weight CAS No 9001-03-0 Molecular Weight 29.0 kDa (Theoretical) 30 kDa (Lindskog et al. 1971) Isoelectric point 6.40 (Theoretical) Composition Sixteen CA isozymes have been described so far in mammals. Erythrocyte CAs, CA-I and CA-II, are most well known. CA-I, CA-II, CA-III, CA-VII, and CA-XIII are cytosolic. CA-IV, CA-IX, CA-XII, CA-XIV, and CA-XV are membrane bound. CA-VI is secreted in saliva. CA-VA and CA-VB are mitochondrial. There are also three acatalytic forms referred to as CA-related proteins (CARPs): CARP-VIII, CARP-X, and CARP-XI (Coban et al. 2009). The zinc metal is always bound to histidines 93, 95, and 118 (mature chain numbering). A hydrogen bonded network, linked to the zinc-bonded water molecule and these histidines either directly or indirectly, includes 28-Ser, 91-Glu, 105-Glu, 106-His, 116-His, 193-Tyr, 198-Thr, 208-Trp, and 223-Asn. These residues have been found to be highly conserved (Lindskog 1982, and Lindskog et al. 1984). Bovine and human CA I and II contain a unique C-terminal knot structure, which has been shown to be important in enzymatic and mechanical properties (Alam et al. 2002). Specificity Blood CO2 transport and excretion is largely dependent on the rapid catalysis of the CO2 reactions within the erythrocyte by CA (Tufts et al. 2003). Bovine CA reversibly hydrates alkyl pyruvates and it exhibits hydratase activity toward a wide variety of substrates (Pocker et al. 1974, and Wells et al. 1975). Unit Definition One Unit is determined by the electrometric method of Wilbur and Anderson (J. Biol. Chem., 176, 147 (1948)), in which the time required (in seconds) for a saturated CO2 solution to lower the pH of 0.02M Tris-HCl buffer from 8.3 to 6.3, at 0-4°C is determined. Optimum pH 7.0-7.5 (Demir et al. 2000, and Tasgin et al. 2009) Activators HPO42-(Rowlett et al. 1991); SO32-(Rowlett et al. 1991) Storage 2-8°C Inhibitors Monovalent anions (Lindskog et al. 1971, and Ward and Cull 1972); Sulfonates and sulfonamides (Pocker and Watamori 1973, and Binford et al. 1974); Imidazole (Edsall 1968) Pathway Bile secretion, organism-specific biosystem; Collecting duct acid secretion, organism-specific biosystem; Metabolism, organism-specific biosystem Function carbonate dehydratase activity; zinc ion binding Synonyms carbonic anhydrases; carbonate dehydratases; EC 4.2.1.1; anhydrase; carbonate anhydrase; carbonic acid anhydrase; carboxyanhydrase; carbonic anhydrase A; carbonate hydro-lyase category Specialty Chemicals(c26) cas_num 9001-03-0 Basic Info-
Product Name:
Carbonic anhydrase
Other Name:Carbonic anhydrase;Dehydratase,carbonate;E.C. 4.2.1.1;Anhydrase;Carbonate anhydrase;Carbonate dehydratase;EC 4.2.1.1;Carbonic acid anhydrase;Carboxyanhydrase;Carbonate anhydrases;Carbonic anhydrases;Preprocarbonic anhydrase;Procarbonic anhydrase;Novozyme NS 81239;Carbonic acid anhydrases;Carbonate dehydratases;Anhydrases;Carboxyanhydrases;9044-52-4;9052-41-9;130303-03-6;130303-05-8
CAS No.:9001-03-0
InChIKeys:IRXYDYDYZGPTNB-UHFFFAOYSA-N
Molecular Weight:397.751
Exact Mass:396.079
HScode:35079090
Categories:
Characteristics-
PSA:
157
Water Solubility:Soluble in water
Hazard IdentificationClassification of the substance or mixture
Respiratory sensitization, Category 1
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Precautionary statement(s) Prevention P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P284 [In case of inadequate ventilation] wear respiratory protection.
Response P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P342+P316 If experiencing respiratory symptoms: Get emergency medical help immediately.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15 days
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Inquiry History4 Inquiries
Country Product Purchase Quantity Date Posted 
France
Carbonic Anhydrase
1 KG Nov 30, 2023
France
Carbonic Anhydrase
1 KG Jul 30, 2025
France
Carbonic anhydrase
100 KG Sep 29, 2025 
Turkey
Carbonic anhydrase manufacturer
500 KG Oct 31, 2023 Post an enquiry for this product
![[Asn670, Leu671]-Amyloid β/A4 Precursor Protein 770 Fragment 667-676 trifluoroacetate salt](https://file.echemi.com/fileManage/upload/canonicalSmiles/20220811/dc320b761764481b983efb671f43b59d.png "[Asn670, Leu671]-Amyloid β/A4 Precursor Protein 770 Fragment 667-676 trifluoroacetate salt")
