LY2157299
1 Inquiries
700874-72-2
99%
2026-06-22
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Inquiry History
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Description
ProductName LY2157299 Cat No CEI-0310 Description LY2157299 can TGF-beta receptor I with IC50 of 56 nM. CAS No 700874-72-2 Molecular Weight 369.42 Purity >99% Storage 2 years at -20centigrade Powder Targets TGF-beta receptor I Molecular Formula C22H19N5O Chemical Name 4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carboxamide Solubility DMSO 74 mg/mL Water In vitro LY2157299 is a new type I receptor TGF-beta kinase inhibitor. LY-2157299 could inhibit TGF-beta-mediated SMAD2 activation and hematopoietic suppression in primary hematopoietic stem cells. In vivo administration of LY-2157299 ameliorated anemia in a TGF-beta overexpressing transgenic mouse model of bone marrow failure. Treatment with LY-2157199 stimulated hematopoiesis from primay MDS bone marrow specimens. category Inhibitors(c1514) cas_num 700874-72-2 Basic Info-
Product Name:
Galunisertib
Other Name:6-Quinolinecarboxamide,4-[5,6-dihydro-2-(6-methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-;4-[5,6-Dihydro-2-(6-methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinolinecarboxamide;LY 2157299;Galunisertib;912477-03-3
CAS No.:700874-72-2
Molecular Formula:C22H19N5O
InChIKeys:InChIKey=IVRXNBXKWIJUQB-UHFFFAOYSA-N
Molecular Weight:369.43
Exact Mass:369.42
UNII:3OKH1W5LZE
DSSTox ID:DTXSID00220362
NCI Thesaurus Code:C116891
HScode:29334900
Categories:
Characteristics-
PSA:
86.7
XLogP3:2.4
Density:1.40
Boiling Point:619.004ºC at 760 mmHg
Flash Point:328.162ºC
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
Slovenia
Galunisertib
10000 MG Mar 24, 2024 Post an enquiry for this product