Camptothecin
1 Inquiries
7689-03-4
95%
2026-06-27
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Inquiry History
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Description
ProductName Camptothecin Cat No CEI-0681 Description Reversibly inhibits nuclear topoisomerase I by binding to and stabilizing the topoisomerase-DNA covalent complex. Inhibits Tat-mediated transcription of HIV-1. Induces apoptosis in Jurkat, osteosarcoma and hepatoma cells. Appearance Liquid Product Overview A topoisomerase I inhibitor CAS No 7689-03-4 Molecular Weight 513.49 Purity >95% by HPLC Storage -20 centigrade Targets TOP1MT Molecular Formula C₂₀H₁₆N₂O₄ Chemical Name (S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione Solubility A 10 mM (1 mg in 195 µl) solution of caspase inhibitor Q-VD-OPh in DMSO. Shipping Conditions Gel pack category Antineoplastic Agents(c1417) cas_num 7689-03-4 Basic Info-
Product Name:
Camptothecin
Other Name:1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,4-ethyl-4-hydroxy-,(4S)-;Camptothecine;1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,4-ethyl-4-hydroxy-,(S)-;(4S)-4-Ethyl-4-hydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;Camptothecin;20(S)-Camptothecine;d-Camptothecin;NSC 94600;(S)-Camptothecin;20(S)-Camptothecin;(+)-Camptothecin;(+)-Camptothecine;MAG-CPT;Campathecin;(S)-(+)-Camptothecin;S-CKD 602;30628-51-4;157405-40-8
CAS No.:7689-03-4
Molecular Formula:C20H16N2O4
InChIKeys:InChIKey=VSJKWCGYPAHWDS-FQEVSTJZSA-N
Molecular Weight:348.35
Exact Mass:348.35
EC Number:444-280-6
UNII:XT3Z54Z28A
NSC Number:94600
DSSTox ID:DTXSID0030956
NCI Thesaurus Code:C338
HScode:29399990
Categories:
Characteristics-
PSA:
79.7
XLogP3:1
Appearance:yellow solid
Density:1.5±0.1 g/cm3
Melting Point:255-277 °C (decomp)
Boiling Point:757.0±60.0 °C at 760 mmHg
Flash Point:411.6±32.9 °C
Refractive Index:1.746
Water Solubility:H2O: insoluble ;chloroform/methanol (4:1): 4 mg/mL
Storage Conditions:2-8°C
Toxicity:Oral-rat LD50: 153 mg/kg; Oral-Mouse LD50: 50.1 mg/kg
Flammability characteristics:Thermal decomposition emits toxic nitrogen oxide fumes; reacts with acids to decompose
Specific rotation:D25 +31.3° (in chloroform-methanol, 8:2)
Collision Cross Section:181.9 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted
India
(S)-(+)-Camptothecin
1000 KG Nov 7, 2024 Post an enquiry for this product