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Pioglitazone

Unit Price: Get Latest Price
CAS No.:

111025-46-8

Content:

99%

Price valid (until):

2026-08-08

Company Type:
Manufactory
Location:
United States
Qualification:
Main Products:

Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

  • Product Description

  • Seller Information

  • Description
    ProductNamePioglitazone
    Cat NoCEI-0383
    DescriptionPioglitazone
    AliasActos
    CAS No111025-46-8
    Molecular Weight356.44
    Purity>99%
    Storage2 years at -20centigrade Powder
    SynonymsActos
    TargetsDPP4
    Molecular FormulaC19H20N2O3S
    SolubilityDMSO 15 mg/mL, Water
    In vitroPioglitazone (Actos) is a selective peroxisome proliferator-activated receptor gamma stimulator. Pioglitazone (Actos) selectively stimulates the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-gamma) and to a lesser extent PPAR-alpha. Pioglitazone (Actos) modulates the transcription of the insulin-sensitive genes involved in the control of glucose and lipid metabolism in the muscle, adipose tissue, and the liver. As a result, pioglitazone (Actos) reduces insulin resistance in the liver and peripheral tissues. Pioglitazone (Actos) increases the expense of insulin-dependent glucose. Pioglitazone (Actos) decreases withdrawal of glucose from the liver. Pioglitazone (Actos) reduces quantity of glucose, insulin and glycated hemoglobin in the bloodstream.
    categoryInhibitors(c1514)
    cas_num111025-46-8

    Basic Info
    Product Name:

    Pioglitazone

    Other Name:

    2,4-Thiazolidinedione,5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-;2,4-Thiazolidinedione,5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-,(±)-;5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione;Pioglitazone;U 72107;5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]thiazolidine-2,4-dione;Zactos;5-[4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzyl]thiazolidine-2,4-dione;(RS)-5-(4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzyl)thiazolidine-2,4-dione;105355-27-9;198077-89-3

    CAS No.:

    111025-46-8

    Molecular Formula:

    C19H20N2O3S

    InChIKeys:

    InChIKey=HYAFETHFCAUJAY-UHFFFAOYSA-N

    Molecular Weight:

    356.44

    Exact Mass:

    356.44

    EC Number:

    1308068-626-2

    Categories:

    Inhibitors

    Characteristics
    PSA:

    93.6

    XLogP3:

    3.8

    Density:

    1.260±0.06 g/cm3(Predicted)

    Melting Point:

    183-184 °C

    Boiling Point:

    575.4±45.0 °C(Predicted)

    Flash Point:

    301.8±28.7 °C

    Refractive Index:

    1.611

    Water Solubility:

    4.42e-03 g/L

    Storage Conditions:

    Store at 25 deg C (77 deg F); excursions permitted to 15-30 deg C (59-86 deg F). Keep container tightly closed, and protect from moisture and humidity.

    Vapor Pressure:

    2.88X10-14 mm Hg at 25 deg C (est)

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    Acute toxicity - Category 4, Dermal

    Acute toxicity - Category 4, Inhalation

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H302+H312+H332 Harmful if swallowed, in contact with skin or if inhaled

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P317 Get medical help.

    P321 Specific treatment (see ... on this label).

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

    Location:

    Shirley, New York 11967, USA

    Payment Terms:

    TT against copy of documents,D/P

    Average lead Time:

    15

    Total Annual Revenue:

    $1 million-$2.5 million

    Year of Establishment:

    2004

    Creative Enzymes is a leading Manufactory supplier of Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- based in America. With a commitment to quality and customer satisfaction, Creative Enzymes has become a trusted name in the industry. Our product line includes a range of high-quality Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-, which are available at competitive prices. Creative Enzymes has established itself as a reliable supplier of chemical products on the echemi.com.

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