Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName IOX1 Cat No CEI-0549 Description Cell-permeable. A histone demethylase (HDM) JMJD nhibitor. Inhibits the JMJD family of 2-oxoglutarate-dependent histone demethylases. IC50s = 0.12, 0.07, 0.2, 0.3, 0.6, and 1 µM for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively. A broad spectrum 2-oxoglutarate oxygenase inhibitor which may be used to study hypoxic signaling. Appearance White solid Product Overview Histone demethylase JMJD inhibitor CAS No 5852-78-8 Molecular Weight 415.28 Purity >95% by HPLC Storage -20 centigrade Targets KDM6B, KDM3A, KDM4A, KDM4E, KDM4C Molecular Formula C 10 H 7 NO 3 Chemical Name 8-Hydroxy-5-quinolinecarboxylic acid; 8-Hydroxy-5-quinolinecarboxylic acid Solubility H₂O (20 mM) and MeOH (5 mg/ml) Shipping Conditions Gel pack category Inhibitors(c1514) cas_num 5852-78-8 Basic Info-
Product Name:
5-Carboxy-8-hydroxyquinoline
Other Name:5-Carboxy-8-hydroxyquinoline;8-Hydroxyquinoline-5-carboxylic Acid;IOX1;8-hydroxy-5-Quinolinecarboxylic acid;IOX 1, >=98%;JMJD2 Inhibitor, 5-carboxy-8HQ
CAS No.:5852-78-8
Molecular Formula:C10H7NO3
InChIKeys:JGRPKOGHYBAVMW-UHFFFAOYSA-N
Molecular Weight:189.16748
Exact Mass:189.042587
UNII:JM015YQC1C
DSSTox ID:DTXSID20207236
HScode:2933499090
Categories:
Characteristics-
PSA:
70.4
XLogP3:1.8
Appearance:white to brown
Density:1.5±0.1 g/cm3
Melting Point:301 °C (decomp)
Flash Point:234.7±24.6 °C
Refractive Index:1.730
Water Solubility:DMSO: soluble10mg/mL, clear
Storage Conditions:2-8°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product