5-Carboxy-8-hydroxyquinoline 99% high purity certified Professional Producer Greenbo
5852-78-8
Pharmaceutical Grade
99%
Shanghai
Greenbo
25kg Drum
2022-07-31
Active Pharm Ingredients,Chemical Catalyst,Pharmaceutical Intermediates,Flavors and Fragrances,Agrochemicals,Chemical Pesticides
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceIOX1 is the most potent broad-spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases; IC50 for KDM4A/KDM3A is 0.6/0.1 uM.IC50 value: 0.6/0.1 uM(KDM4A/KDM3A) [1]Target: JmjC KDMs inhibitorIOX1 is the most potent against a representative panel of 2OG oxygenases, including non-JmjC 2OG oxygenases, with an in vitro IC50 value in the micromolar range. However, its efficacy in cells is about a hundred-fold lower (HeLa cells, KDM4A, IC50 = 86uM), possibly due to low cell permeabi
8-hydroxy-5-quinolinecarboxylic acid is a member of quinolines.Basic Info-
Product Name:
5-Carboxy-8-hydroxyquinoline
Other Name:5-Carboxy-8-hydroxyquinoline;8-Hydroxyquinoline-5-carboxylic Acid;IOX1;8-hydroxy-5-Quinolinecarboxylic acid;IOX 1, >=98%;JMJD2 Inhibitor, 5-carboxy-8HQ
CAS No.:5852-78-8
Molecular Formula:C10H7NO3
InChIKeys:JGRPKOGHYBAVMW-UHFFFAOYSA-N
Molecular Weight:189.16748
Exact Mass:189.042587
UNII:JM015YQC1C
DSSTox ID:DTXSID20207236
HScode:2933499090
Categories:
Characteristics-
PSA:
70.4
XLogP3:1.8
Appearance:white to brown
Density:1.5±0.1 g/cm3
Melting Point:301 °C (decomp)
Flash Point:234.7±24.6 °C
Refractive Index:1.730
Water Solubility:DMSO: soluble10mg/mL, clear
Storage Conditions:2-8°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Active Pharm Ingredients,Chemical Catalyst,Pharmaceutical Intermediates,Flavors and Fragrances,Agrochemicals,Chemical Pesticides
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Location:
Zone K,Zwei Tianyuan Dushi Est,New Industial Park,High-tech Zone, Xian City,Shaanxi
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Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
15 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2017
Company Certificates-
international trade license
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FSSC2000
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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