Alsterpaullone
237430-03-4
96%
2026-07-05
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Alsterpaullone Cat No CEI-0957 Description A potent and selective inhibitor of GSK-3beta and CDK5/p25. Potent inhibitor of CDK1/Cyclin B (IC50=35 nM). Induces apoptosis. Inhibits angiogenesis. Abbr Alsterpaullone(GSK3B, CDK5, CDK5R1) Alias 9-Nitro-7, 12-dihydroindolo-[3, 2-d][1] benzazepin-6(5)-one Appearance Brown crystalline powder Product Overview GSK-3beta and CDK5/p25 inhibitor. CAS No 237430-03-4 Molecular Weight 293.3 Purity >96% (TLC); NMR (Conforms) Synonyms 9-Nitro-7,12-dihydroindolo-[3,2-d][1] benzazepin-6(5)-one Targets GSK-3beta, CDK5/p25 Molecular Formula C16H11N3O3 Solubility May be dissolved in DMSO (10 mg/ml) category Specialty Chemicals(c26) cas_num 237430-03-4 Basic Info-
Product Name:
Alsterpaullone
Other Name:Indolo[3,2-d][1]benzazepin-6(5H)-one,7,12-dihydro-9-nitro-;7,12-Dihydro-9-nitroindolo[3,2-d][1]benzazepin-6(5H)-one;Alsterpaullone;9-Nitropaullone;NSC 705701;9-Nitro-7,12-dihydroindolo-(3,2-d)(1)benzazepin-6(5H)-one;959569-16-5
CAS No.:237430-03-4
Molecular Formula:C16H11N3O3
InChIKeys:InChIKey=OLUKILHGKRVDCT-UHFFFAOYSA-N
Molecular Weight:293.28
Exact Mass:293.28
HScode:2933990090
Categories:
Characteristics-
PSA:
90.7
XLogP3:2.4
Appearance:brown powder
Density:1.5±0.1 g/cm3
Melting Point:>330 °C
Flash Point:347.8±28.7 °C
Refractive Index:1.738
Water Solubility:DMSO: soluble
Storage Conditions:2-8°C
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product