Senicapoc
289656-45-7
0.98%
2026-07-06
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Senicapoc Cat No CEI-1526 Product Overview Senicapoc is a potent inhibitor of the Gardos channel and ameliorates RBC dehydration in the SAD mouse. Senicapoc blocked Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 ±2 nM (CLT IC50 = 100 ±12 nM) and inhibited RBC dehydration with an IC50 of 30 ±20 nM. Senicapoc is in treatment of Sickle Cell Disease and Sickle Cell Anemia CAS No 289656-45-7 Molecular Weight 323.35 Purity 0.98 Storage Store at -20°C Synonyms ICA-17043; ICA 17043; ICA17043 Targets Gardos channel; RBC Molecular Formula C20H15F2NO Chemical Name 2,2-bis(4-fluorophenyl)-2-phenylacetamide Solubility Soluble in DMSO Shipping Conditions Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request category Specialty Chemicals(c26) cas_num 289656-45-7 Basic Info-
Product Name:
Senicapoc
Other Name:Benzeneacetamide,4-fluoro-α-(4-fluorophenyl)-α-phenyl-;4-Fluoro-α-(4-fluorophenyl)-α-phenylbenzeneacetamide;ICA 17043;Senicapoc;2,2-Bis(4-fluorophenyl)-2-phenylacetamide
CAS No.:289656-45-7
Molecular Formula:C20H15F2NO
InChIKeys:InChIKey=SCTZUZTYRMOMKT-UHFFFAOYSA-N
Molecular Weight:323.34
Exact Mass:323.34
UNII:TS6G201A6Q
DSSTox ID:DTXSID60276906
HScode:2924299090
Categories:
Characteristics-
PSA:
43.1
XLogP3:4.1
Density:1.25g/cm3
Melting Point:180-181 °C @ Solvent: Hexane, Dichloromethane
Boiling Point:460.7°C at 760 mmHg
Flash Point:232.4ºC
Refractive Index:1.594
Vapor Pressure:1.14E-08mmHg at 25°C
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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