Vincristine Sulfate
2 Inquiries
2068-78-2
98%
2026-08-26
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Inquiry History
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Description
ProductName Vincristine Sulfate Cat No CSUB-0947 Description Vincristine Sulfate, a dimeric Vinca alkaloid, has been shown to bind to Tubulin via a protein self association reaction. This compound acts as a Tubuiln inhibitor by binding to sites at the ends of microtubules, which regulate the inhibition of Tubulin dimer addition to microtubule ends. Experiments have reported Vincristine Sulfate to demonstrate a capacity to suppress growth of proliferating cells through marked apoptosis and cell cycle arrest at G2/M. The cell death caused by this agent seems to result in a sustained accumulation of endogenous ceramide levels. Ceramide, has been proposed as a lipid second messenger with specific antiproliferative mediating responses. Vincristine Sulfate is an inhibitor of MAO. Vincristine Sulfate is also a substrate of PGP and CYP3A4. Applications A cell cycle arresting, apoptotic inducing alkaloid Form Solid CAS No 2068-78-2 Molecular Weight 923.04 Purity >98% Storage Store at -20° C Synonyms 22-Oxovincaleukoblastine Sulfate; Leurocristine Sulfate; Kyocristine; Lilly 37231; NSC 67574; Novopharm; Oncovin; Onkovin; VCR Sulfate; Vincasar PFS; Vincrisul Molecular Formula C46H56N4O10•H2SO4 MDL Number MFCD00084729 Melting Point 300° C Solubility Soluble in water (25 mg/ml), ethanol, and methanol. Substrates PKA; CKII; PKCα category Antineoplastic Agents(c1417) cas_num 2068-78-2 Basic Info-
Product Name:
Vincristine sulfate
Other Name:Vincaleukoblastine,22-oxo-,sulfate (1:1);Leurocristine,sulfate (1:1) (salt);Leurocristine sulfate;Vincaleukoblastine,22-oxo-,sulfate (1:1) (salt);NSC 67574;Oncovin;Vincristine sulfate;Onkovin;Vincasar PFS;Kyocristine;Vincrisul;VCR sulfate;Lilly 37231;Novopharm;Marqibo;Vincristine hydrogen sulfate;Vincristine sulfate liposome injection
CAS No.:2068-78-2
Molecular Formula:C46H56N4O10.H2O4S
InChIKeys:InChIKey=AQTQHPDCURKLKT-PNYVAJAMSA-N
Molecular Weight:923.04
Exact Mass:922.367004
EC Number:218-190-0
NSC Number:67574
UN Number:1544
DSSTox ID:DTXSID8044331
HScode:2942000000
Categories:
Characteristics-
PSA:
254.15000
XLogP3:4.52220
Appearance:white to off-white lyophilized powder
Melting Point:300 °C
Boiling Point:273-281 °C
Water Solubility:H2O: >=1 g/100 mL at 24 ºC;methanol: soluble 20mg/mL
Storage Conditions:2-8°C
Toxicity:LD50 intraperitoneal in mouse: 3mg/kg
Specific rotation:D26 +8.5° (c = 0.8)
Collision Cross Section:281 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Air and Water Reactions:Very hygroscopic. Water soluble.
Reactive Group:Alcohols and Polyols
Reactivity Profile:Sensitive to hydrolysis, oxidation and heat. Incompatible with strong oxidizing agents. (NTP, 1992).
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 2, Oral
Germ cell mutagenicity, Category 2
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H300 Fatal if swallowed
H341 Suspected of causing genetic defects
H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted 
India
Vincristine sulphate
1.00 G Sep 4, 2025
India
VINCRISTINE SULPHATE USP
22.00 KG Jul 4, 2025 Post an enquiry for this product