555-30-6
2 Inquiries
555-30-6
kg
2023-02-05
Custom Synthetic Chemicals,Biological Stains,Pharmaceutical Intermediates,Cosmetic Grade Chemicals,Enzyme,Nucleosides
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Product Description
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Seller Information
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Inquiry History
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DescriptionBasic Info
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Product Name:
Methyldopa
Other Name:L-Tyrosine,3-hydroxy-α-methyl-;Alanine,3-(3,4-dihydroxyphenyl)-2-methyl-,L-;3-Hydroxy-α-methyl-L-tyrosine;MK 351;Nr.C 2294;Aldomet;Levo-3-(3,4-Dihydroxyphenyl)-2-methylalanine;L-(-)-β-(3,4-Dihydroxyphenyl)-α-methylalanine;L-α-Methyl-3,4-dihydroxyphenylalanine;L-(-)-α-Methyl-β-(3,4-dihydroxyphenyl)alanine;Methyldopa;α-Methyl-L-3,4-dihydroxyphenylalanine;Presinol;(-)-α-Methyl-3,4-dihydroxyphenylalanine;l-3-(3,4-Dihydroxyphenyl)-2-methylalanine;Dopegyt;α-Methyldopa;(-)-Methyldopa;l-α-Methyldopa;α-Methyl-L-dopa;(S)-(-)-α-Methyldopa;L-2-Amino-2-methyl-3-(3,4-dihydroxyphenyl)propionic acid;AMD;Aldometil;Aldomin;Dopamet;Sembrina;Dopatec;Medomet;Medopren;Methoplain;Alpha medopa;Bayer 1440L;Baypresol;Presolisin;Alphamethyldopa;2-Methyl-3-(3,4-dihydroxyphenyl)alanine;(-)-α-Methyldopa;L-3,4-Dihydroxyphenyl-2-methylalanine;(S)-α-Methyldopa;Methyl-L-dopa;L-α-Methyldopa;L-3,4-Dihydroxy-α-methylphenylalanine;L-Methyldopa;L-α-Methyl-3-(3,4)-dihydroxyphenylalanine;Equibar;Aldomine;Medopa;Lederdopa;Elanpres;NSC 169916;Aldochlor;(2S)-2-Amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid;133161-54-3;779-08-8;1339-75-9;4290-08-8;88620-56-8
CAS No.:555-30-6
Molecular Formula:C10H13NO4
InChIKeys:InChIKey=CJCSPKMFHVPWAR-JTQLQIEISA-N
Molecular Weight:211.21
Exact Mass:211.21
EC Number:209-089-2
UNII:M4R0H12F6M
NSC Number:760080
DSSTox ID:DTXSID5020863|DTXSID5023295
Color/Form:Minute, anhyd crystals from methanol|WHITE TO YELLOWISH WHITE, FINE POWDER, WHICH MAY CONTAIN FRIABLE LUMPS
ATC Code:C - Cardiovascular system
HScode:2918199090
Categories:
Characteristics-
PSA:
104
XLogP3:-1.79
Appearance:Methyl dopa appears as colorless or almost colorless crystals or white to yellowish-white fine powder. Almost tasteless. In the sesquihydrate form. pH (saturated aqueous solution) about 5.0. (NTP, 1992)
Density:1.4±0.1 g/cm3
Melting Point:300 °C (decomp)
Boiling Point:441.6±45.0 °C at 760 mmHg
Flash Point:220.9±28.7 °C
Refractive Index:1.635
Water Solubility:H2O: 10g/L(temperature not stated)
Storage Conditions:Store at RT
Toxicity:LD50 oral in rabbit: 713mg/kg
Specific rotation:Max absorption: 281 nm (e= 2780); Specific optical rotation (1 in 0.1 N HCl): -4.0 +/- 0.5 deg @ 23 °C/D
Odor:ODORLESS
Taste:ALMOST TASTELESS
PH:pH of saturated aq soln about 5.0
Collision Cross Section:147.6 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|146.8 Ų [M+Na]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Experimental Properties:Considerably hygroscopic; decomp @ approx 300 °C; exists as sesquihydrate|Crystals from water /sesquihydrate/
Air and Water Reactions:Very hygroscopic. Slightly water soluble. May be sensitive to prolonged exposure to air and light. The stability of aqueous solutions is markedly dependent on pH, oxygen and the amount of initial reactant. Aqueous solutions are stable for up to 50 hours in acid and neutral pH (6.2). At pH 8.0, decomposition products are formed in 3 to 5 hours. Solutions develop a red tint that becomes progressively darker (eventually forming a black precipitate).
Reactive Group:Acids, Carboxylic
Reactivity Profile:METHYL DOPA undergoes catalytic oxygenation in the presence of magnesium, cupric, cobalt, nickel and ferric ions (NTP, 1992). A weakly acidic amino acid.
Hazard IdentificationClassification of the substance or mixture
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Methyldopa oral suspension should be stored in tight, light-resistant containers at a temperature less than 26 deg C and protected from freezing. Methyldopa tablets should be stored in well-closed containers at a temperature less than 40 deg C, preferably at 15-30 deg C.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Custom Synthetic Chemicals,Biological Stains,Pharmaceutical Intermediates,Cosmetic Grade Chemicals,Enzyme,Nucleosides
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Location:
Room 308-80, building 1, 1963 Huaguan Road, Tianhe District, Guangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,100% TT in advance
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Average lead Time:
30
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2021
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted
Pakistan
Methyldopa
2000 KG Sep 13, 2023
Pakistan
Methyldopa
75 KG Sep 11, 2023 Post an enquiry for this product