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Folinic Acid 58-05-9

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CAS No.:

58-05-9

Grade:

Pharmaceutical Grade

Content:

99.9%

Port:

any port in China

Packaging:

25kg/Cardboard Drum

Price valid (until):

2023-03-29

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NANTONG REFORM PETRO-CHEMICAL CO.,LTD

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Flavors & Fragrances,Catalyst & Auxiliary,Intermediates,Dyes & Pigments,Inorganic Chemistry,petro chemicals

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Product Description
Seller Information
Inquiry History

Description

Basic Information
Product Name	Folinic Acid
Multiple Names	Folinic Acid； -Formyl-5,6,7,8-Tetrahydropteroyl-l-Glutamicacid;Leucoverin; -Formyl-5,6,7,8-Tetrahydrofolate; -Formyltetrahydrofolate; -Formyltetrahydrofolicacid; N5-Formychemicalbookl-5,6,7,8-Tetrahydrofolate; N5-Formyl-Tetrahydrofolate; 2-[4-[(2-Amino-5-Formyl-4-Oxo-1,6,7,8-Tetrahydropteridin-6-Yl)Methylamino]Benzoyl]Aminopentanedioicacid
CAS No.	58-05-9
EC No.	200-361-6
MF No.	C20H23N7O7
MW No.	473.4393

Product Usage

Folic acid (calcium folinate) is a special form of reduced folic acid (folate). High dose folic acid intervention in children with CFD can improve their neurological and developmental abnormalities. Abnormal folate metabolism is related to the occurrence of autism in children. The genetic polymorphism of folate related pathway may lead to abnormal folate metabolism.

Specification
Assay Item	Standard
Form	Powder
Color	White
Boiling point	573.92°C
Melting Point	245°C
Density	1.4485

Basic Info

Product Name:

Folinic acid

Other Name:

5-formyl-5,6,7,8-tetrahydropteroyl-l-glutamicacid;leucoverin;5-formyl-5,6,7,8-tetrahydrofolate;5-formyltetrahydrofolate;5-formyltetrahydrofolic acid;N5-formyl-5,6,7,8-tetrahydrofolate;N5-formyl-tetrahydrofolate;2-[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]aminopentanedioic acid

CAS No.:

58-05-9

Molecular Formula:

C20H23N7O7

InChIKeys:

VVIAGPKUTFNRDU-ABLWVSNPSA-N

Molecular Weight:

473.44

Exact Mass:

473.44

EC Number:

200-361-6

DSSTox ID:

DTXSID3036999|DTXSID0048216

Color/Form:

Pale Yellow to Light Yellow

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

219.84000

XLogP3:

1.15290

Density:

1.4485 (rough estimate)

Melting Point:

245°C (rough estimate)

Boiling Point:

573.92°C (rough estimate)

Refractive Index:

1.6800 (estimate)

Water Solubility:

>1350g/L(25 ºC)

Vapor Pressure:

2.3X10-21 mm Hg at 25 °C at 25 °C /Estimated/

Specific rotation:

D20 +14.26° (c = 3.42 as anhydr Ca salt)

PH:

pH of saturated solution in water = 2.8-3.0.

PKA:

3.1, 4.8, 10.4(at 25℃)

Henrys Law Constant:

Henry's Law constant = 4.4X10-27 atm-cu m/mole at 25 °C /Estimated/

Dissociation Constants:

pKa1= 3.1; pKa2= 4.8; pKa3= 10.4

Experimental Properties:

Crystals; decompose 240-250 °C; sparingly soluble in water. /dl-Folinic acid/|Hydroxyl radical reaction rate constant = 2.7X10-10 cu cm/molec-sec at 25 °C /Estimated/

Critical Temperature & Pressure:

under inert gas (nitrogen or Argon) at 2–8 °C

See More Folinic acid Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Folinic acid Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Flavors & Fragrances,Catalyst & Auxiliary,Intermediates,Dyes & Pigments,Inorganic Chemistry,petro chemicals

Location:
17th Yuanlin Road ,Chongchuan area ,Nantong city ,Jiangsu province ,China

Payment Terms:
L/C,100% TT in advance

Average lead Time:
2

Total Annual Revenue:
Above $100 million

Total Employees:
201-300

Year of Establishment:
2008

Certifications:
GB/T19001-2016 / Iso9001:2015

Established in 2008, running 14 years in Chemicals,
with over one hundred staff ,selling thousand items, over RMB 1billion turnover annually.
Regist ISO9001(No:31622Q10628ROM)
Especially in the research, development and production of : Chemical raw materials,fine chemicals,pharmaceutical intermediates,Agrochemicals,food additives,Electronic chemicals,Environmental protection and water treatment...etc.
We specialize in these field with the strength of good quality, pretty competitive price,and good service.

Inquiry History

5 Inquiries

Country	Product	Purchase Quantity	Date Posted
Qatar	folinic acid	1 KG	Feb 27, 2024
Latvia	Folinic acid	1 20' Fcl	Mar 4, 2026
Australia	Leucovorin	1 KG	Oct 21, 2025
Netherlands	Folinic acid	5 KG	Mar 18, 2026
United States	leucovorin	10 MG	Sep 23, 2025

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