Glucuronolactone

 Glucuronolactone is a chemical. It can be made by the body. It is also found in foods and made in laboratories.
   Glucuronolactone is a popular ingredient in energy drinks because it has been shown to be effective at increasing energy levels and improving alertness.Glucuronolactone supplementation also significantly reduces "brain fog" cause by various medical conditions. Although levels of glucuronolactone in energy drinks can far exceed those found in the rest of the diet, glucuronolactone is extremely safe and well tolerated.The European Food Safety Authority (EFSA) has concluded that exposure to glucuronolactone from regular consumption of energy drinks is not a safety concern.The no-observed-adverse-effect level of glucuronolactone is 1000 mg/kg/day.

   Additionally, according to The Merck Index, glucuronolactone is used as a detoxicant.The liver uses glucose to create glucuronolactone, which inhibits the enzyme B-glucuronidase (metabolizes glucuronides), which should cause blood-glucuronide levels to rise. Glucuronides combine with toxic substances, such as morphine and depot medroxyprogesterone acetate, by converting them to water-soluble glucuronide-conjugates which are excreted in the urine.Higher blood-glucuronides help remove toxins from the body, leading to the claim that energy drinks are detoxifying. Free glucuronic acid (or its self-ester glucuronolactone) has less effect on detoxification than glucose,[citation needed] because the body synthesizes UDP-glucuronic acid from glucose. Therefore, sufficient carbohydrate intake provides enough UDP-glucuronic acid for detoxication,[citation needed] and foods rich in glucose are usually abundant in developed nations.

    Glucuronolactone is also metabolized to glucaric acid, xylitol, and L-xylulose, and humans may also be able to use glucuronolactone as a precursor for ascorbic acid synthesis

   The main function of glucuronolactone is to enhance the detoxification function of liver, recover or improve brain function, regulate immune function, nourish skin, delay aging, improve hypoxia, eliminate fatigue, and enhance the control and coordination ability of various organ functions. For acute and chronic hepatitis, cirrhosis, or for food or drug poisoning detoxification。

Packaging and storage: 25kg cartons.

Storage precautions: store in cool, dry and well ventilated warehouse. Keep away from fire and heat sources. Protect from direct sunlight. The package must be sealed and protected from dampness.

Application: food additive, pharmaceutical intermediate